QIUQIANG CHEN1,*, XIAOLEI ZHAO2, WENXUE MA3,*
Oncology Research, Vol.32, No.1, pp. 95-98, 2024, DOI:10.32604/or.2023.046174
Abstract Greenblatt and his team have unveiled vertebral skeletal stem cells (vSSCs) as a critical player in the landscape
of bone metastasis. This commentary delves into the transformative discoveries surrounding vSSCs, emphasizing their
distinct role in bone metastasis compared to other stem cell lineages. We illuminate the unique properties and
functions of vSSCs, which may account for the elevated susceptibility of vertebral bones to metastatic invasion.
Furthermore, we explore the exciting therapeutic horizons opened by this newfound understanding. These include
potential interventions targeting vSSCs, modulation of associated signaling pathways, and broader implications for the
treatment and management of bone metastasis. By… More >
Graphic Abstract
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