Oncology Research Editorial Office

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.077268 - 30 December 2025

Abstract This article has no abstract. More >

Abdulrahman K. Sinno¹, Aisha Mustapha¹, Navya Nair¹, Simona Zaami², Lina De Paola², Valentina Billone³, Eleonora Conti³, Giuseppe Gullo^3,*, Pasquale Patrizio⁴

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.072176 - 30 December 2025

Abstract Cervical cancer related to human papillomavirus (HPV) is a leading cause of cancer-related mortality among women worldwide. Cancer cells release fragments of their DNA, known as circulating tumor DNA (ctDNA), which can be detected in bodily fluids. A PubMed search using the terms “ctHPV” or “circulating tumor DNA” and “cervical cancer”, limited to the past ten years, identified 104 articles, complemented by hand-searching for literature addressing medico-legal implications. Studies were evaluated for relevance and methodological quality. Detection and characterization of circulating tumor HPV DNA (ctHPV DNA) have emerged as promising tools for assessing prognosis and More >

Mustansar Mubeen¹, Yasir Iftikhar^1,*, Ganesan Vadamalai^2,3, Muhammad Aasim⁴, Muhammad Faiq⁵, Uthman Balgith Algopishi⁶, Ahmed Ezzat Ahmed^6,7

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3827-3843, 2025, DOI:10.32604/phyton.2025.071555 - 29 December 2025

Abstract Citrus viroids are small non-coding RNA pathogens that pose a significant threat to global citrus production by reducing fruit yield, quality, and tree longevity. Several viroids, including Citrus exocortis viroid (CEVd), Hop stunt viroid (HSVd), Citrus bent leaf viroid (CBLVd), and newly identified members such as Citrus Viroid VI (CVd-VI) and Citrus Viroid VII (CVd-VII) have been reported from diverse citrus-growing regions. These pathogens are transmitted mainly through vegetative propagation, contaminated tools, and occasionally via seed or pollen, making their management complex. This review synthesizes current knowledge on the biology, structural diversity, transmission, symptomatology, detection,… More >

Maysaa Al-Qurashi¹, Ayesha Siddiqa², Shazia Karim³, Yu-Ming Chu^4,5,*, Saima Rashid^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2057-2129, 2025, DOI:10.32604/cmes.2025.071629 - 26 November 2025

Abstract Chikungunya is a mosquito-borne viral infection caused by the chikungunya virus (CHIKV). It is characterized by acute onset of high fever, severe polyarthralgia, myalgia, headache, and maculopapular rash. The virus is rapidly spreading and may establish in new regions where competent mosquito vectors are present. This research analyzes the regulatory dynamics of a stochastic differential equation (SDE) model describing the transmission of the CHIKV, incorporating seasonal variations, immunization efforts, and environmental fluctuations modeled through Poisson random measure noise under demographic heterogeneity. The model guarantees the existence of a global positive solution and demonstrates periodic dynamics… More >

Norbert Nass^1,2,#, Mohamad-Kamal Yaakoub^1,#, Alexandra-Victorita Simion³, Hartmut Kroll⁴, Sabine Westphal³, Judith Pannier¹, Gerhard Behre^1,*

Oncology Research, Vol.33, No.10, pp. 2923-2935, 2025, DOI:10.32604/or.2025.067561 - 26 September 2025

Abstract Background: Patients with hemato-oncological malignancies may respond insufficiently to vaccination, especially in terms of antibody titer. The antibody response depends on the type of malignancy as well as the type and timing of treatment. We intended to evaluate this using real-world data from patients of our regional hospital. This study also considers the role of immune status, including T-cell activation markers, in predicting vaccination success. Methods: Seventeen patients of our hospital having a hematological malignancy were included in this study, including myeloma, lymphoma, as well as acute myeloid leukemia (AML) and chronic lymphoid leukemia (CLL).… More >

CHIOMA C. EZEUKO^#, SANDANI V. T. WIJERATHNE^#, QIANA L. MATTHEWS^*

BIOCELL, Vol.49, No.9, pp. 1605-1629, 2025, DOI:10.32604/biocell.2025.065474 - 25 September 2025

Abstract Extracellular vesicles (EVs) have arisen as potential therapeutic tools in managing infectious diseases because EVs can regulate cell-to-cell signaling, function as drug transport mechanisms, and influence immune reactions. They are obtained from a myriad of sources, such as plants, humans, and animal cells. EVs like exosomes and ectosomes can be utilized in their native form as therapeutics or engineered to encompass antimicrobials, vaccines, and oligonucleotides of interest with a targeted delivery strategy. An in-depth understanding of host-pathogen dynamics provides a solid foundation for exploiting its full potential in therapeutics against infectious diseases. This review mainly More >

Chuhan Zhao^1,*, Souad Morsli², Laurent Caramelle³, Mohammed El Ganaoui³

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.8, pp. 2001-2025, 2025, DOI:10.32604/fdmp.2025.068093 - 12 September 2025

Abstract Carbon dioxide (CO₂) is often monitored as a convenient yardstick for indoor air safety, yet its ability to stand in for pathogen-laden aerosols has never been settled. To probe the question, we reproduced an open-plan office at full scale (7.2 m 5.2 m 2.8 m) and introduced a breathing plume that carried 4% CO₂, together with a polydisperse aerosol spanning 0.5–10 m (1320 particles s⁻¹). Inlet air was supplied at 0.7, 1.4, and 2.1 m s⁻¹, and the resulting fields were simulated with a Realisable – RANS model coupled to Lagrangian particle tracking. Nine strategically placed probes… More >

Zichen Li^1,#, Jukui Ma^2,#, Minjun Liu³, Guowei Geng^1,*, Hongxia Zhang^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.6, pp. 1841-1856, 2025, DOI:10.32604/phyton.2025.066148 - 27 June 2025

Abstract Sweet potatoes are significant cash crops, however, their yield and quality are greatly compromised by viral diseases. In this study, the complete genomic sequences of two Sweet Potato Virus 2 (SPV2) isolates from infected sweet potato leaves in the Shandong (designated as SPV2-SDYT, GenBank No. PQ855660.1) and Jiangsu (designated as SPV2-JSXZ, GenBank No. PQ855661.1) provinces in China were obtained using 5^′ RACE and RT-PCR amplification. Consistency, phylogeny, codon usage bias, recombination, and selection pressure analyses were conducted using the SPV2-SDYT and SPV2-JSXZ genome sequences. The complete genome sequences of SPV2-SDYT and SPV2-JSXZ were 10561 nucleotides (nt)… More >

YUYU YE, YING LIU^*

Oncology Research, Vol.33, No.7, pp. 1593-1610, 2025, DOI:10.32604/or.2025.061857 - 26 June 2025

Abstract Liver cancer is the fifth most common cancer in the world, with China bearing a disproportionate burden of cases. Typically diagnosed at advanced stages, liver cancer often utilizes surgical treatments such as resection, transcatheter hepatic artery chemoembolization (TACE), and radiofrequency ablation. However, advancements in genetic engineering and tumor immunology have unveiled the distinct potential of targeted oncolytic virus therapy. Oncolytic virus, in particular, can selectively destroy tumor cells without harming normal cells, offering a promising avenue for liver cancer treatment through immune system activation, tumor microenvironment modulation, and other mechanisms. This review describes the mechanism More >

Federico Licastro^*

BIOCELL, Vol.49, No.6, pp. 981-989, 2025, DOI:10.32604/biocell.2025.062303 - 24 June 2025

Abstract Alzheimer’s disease (AD) is a neurodegenerative disease causing the most frequent form of dementia in old age. AD etiology is still uncertain and deposition of abnormal proteins in the brain along with chronic neuroinflammation have been suggested as pathogenic mechanisms of neuronal death. Infections by exogenous neurotropic virus, endogenous retrovirus reactivation, infections by other microbes, and air pollutants may either induce neurodegeneration or activate brain inflammation. Up to 8% of the human genome has a retroviral origin. These ancient retroviruses, also called human endogenous retroviruses, are associated with a clinical history of several neurodegenerative diseases.… More >