Jiali Wang¹, Xiangmei Chen¹, Xiaozhen Huang¹, Yichen Zhao^1,*, Degang Zhao^1,2,*

Phyton-International Journal of Experimental Botany, Vol.92, No.5, pp. 1377-1389, 2023, DOI:10.32604/phyton.2023.026830

Abstract The phytoene desaturase (PDS) encodes a crucial enzyme in the carotenoid biosynthesis pathway. Silencing or inhibiting PDS expression leads to the appearance of mottled, chlorosis, or albino leaves. In this study, the CDS sequence of EuPDS (Eucommia ulmoides Phytoene Desaturase) was first cloned and then PDS was silenced in Nicotiana benthamiana. Result showed the expression level of EuPDS in leaves was higher than that in the roots and stems. In N. benthamiana leaves, which were treated by Agrobacterium for 24 h, photo-bleaching was shown on the fresh leaves one week after injection and the transcript level of PDS was down-regulated… More >

SUBHASH CHANDRA^1,2, SANTWANA PALAI³, EDINARDO FAGNER FERREIRA-MATIAS⁴, IVO CAVALCANTE PITA-NETO⁴, CíCERO LUCAS GOMES-RAMALHO⁴, EDLANE MARTINS DE ANDRADE⁴, RAY SILVA DE ALMEIDA⁵, MARCELLO IRITI^6,7,*, HENRIQUE DOUGLAS MELO-COUTINHO^5,*

BIOCELL, Vol.47, No.4, pp. 677-695, 2023, DOI:10.32604/biocell.2023.026081

Abstract Indian medicinal plants are referred to as the “nectar of life” owing to their phytochemicals and bioactive complexes that are beneficial in treating diseases. Coronavirus disease 2019 (COVID-19) is a global health issue without any proper medication. The indigenous plants of India can be exploited to control the precise signs of SARS-CoV-2. The Ministry of AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) has advised routine usage of medicinal plants for COVID-19. Medicinal plants like Zingiber officinalis, Azadirachta indica, Ocimum sanctum, Nigella sativa, Withania somnifera, Curcuma longa, Piper nigrum, Allium sativum, Tinospora cordifolia, etc. have immunity-boosting, antiviral, antibacterial, antioxidant… More >

Mohammad Aslefallah¹, Şuayip Yüzbaşi², Saeid Abbasbandy^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.2, pp. 1687-1706, 2023, DOI:10.32604/cmes.2023.025647

Abstract In this work, the exponential approximation is used for the numerical simulation of a nonlinear SITR model as a system of differential equations that shows the dynamics of the new coronavirus (COVID-19). The SITR mathematical model is divided into four classes using fractal parameters for COVID-19 dynamics, namely, susceptible (S), infected (I), treatment (T), and recovered (R). The main idea of the presented method is based on the matrix representations of the exponential functions and their derivatives using collocation points. To indicate the usefulness of this method, we employ it in some cases. For error analysis of the method, the… More > Graphic Abstract

Suthep Suantai^1,2, Zulqurnain Sabir^3,4, Muhammad Asif Zahoor Raja⁵, Watcharaporn Cholamjiak^6,*

CMC-Computers, Materials & Continua, Vol.75, No.1, pp. 2155-2170, 2023, DOI:10.32604/cmc.2023.034699

Abstract The purpose of this study is to present the numerical performances and interpretations of the SEIR nonlinear system based on the Zika virus spreading by using the stochastic neural networks based intelligent computing solver. The epidemic form of the nonlinear system represents the four dynamics of the patients, susceptible patients S(y), exposed patients hospitalized in hospital E(y), infected patients I(y), and recovered patients R(y), i.e., SEIR model. The computing numerical outcomes and performances of the system are examined by using the artificial neural networks (ANNs) and the scaled conjugate gradient (SCG) for the training of the networks, i.e., ANNs-SCG. The… More >

Michael Galvin^1,2,3,*, Guesly Michel³, Henri-Claude Saintelmond⁴, Carolyn Lesorogol⁵, Jean-François Trani⁵, Lora Iannotti⁵

International Journal of Mental Health Promotion, Vol.25, No.2, pp. 173-191, 2023, DOI:10.32604/ijmhp.2023.018800

Abstract In recent decades, Haiti has been subject to man-made and natural disasters that have left its citizens vulnerable to a range of shocks. With a weak state unable to protect its populace, Haitians are exposed to some of the highest levels of poverty and violence in the Western Hemisphere. In recent years, Haitians have experienced two crises that this study analyzes: the instability and political violence of “peyi lòk” as well as the global pandemic of COVID-19. This community-based assessment explores the impact of these two crises on the mental health and psychological well-being of 38 Haitian university students in… More >

Ali Raza¹, Dumitru Baleanu^2,3,4, Zafar Ullah Khan⁵, Muhammad Mohsin^6,*, Nauman Ahmed⁷, Muhammad Rafiq⁸, Pervez Anwar⁹

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.1, pp. 257-275, 2023, DOI:10.32604/cmes.2023.023231

Abstract Most developing countries such as Afghanistan, Pakistan, India, Bangladesh, and many more are still fighting against poliovirus. According to the World Health Organization, approximately eighteen million people have been infected with poliovirus in the last two decades. In Asia, still, some countries are suffering from the virus. The stochastic behavior of the poliovirus through the transition probabilities and non-parametric perturbation with fundamental properties are studied. Some basic properties of the deterministic model are studied, equilibria, local stability around the stead states, and reproduction number. Euler Maruyama, stochastic Euler, and stochastic Runge-Kutta study the behavior of complex stochastic differential equations. The… More >

Kamal Shah^1,2, Hafsa Naz², Thabet Abdeljawad^1,3,*, Bahaaeldin Abdalla¹

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.1, pp. 921-941, 2023, DOI:10.32604/cmes.2023.025769

Abstract This research aims to understand the fractional order dynamics of the deadly Nipah virus (NiV) disease. We focus on using piecewise derivatives in the context of classical and singular kernels of power operators in the Caputo sense to investigate the crossover behavior of the considered dynamical system. We establish some qualitative results about the existence and uniqueness of the solution to the proposed problem. By utilizing the Newtonian polynomials interpolation technique, we recall a powerful algorithm to interpret the numerical findings for the aforesaid model. Here, we remark that the said viral infection is caused by an RNA type virus… More > Graphic Abstract

QIAOJIN JIA^1,2, YUEJUN FU^1,*

BIOCELL, Vol.47, No.3, pp. 627-645, 2023, DOI:10.32604/biocell.2023.026182

Abstract Background: The immune system of insects exerts fundamentally different antiviral mechanisms than mammals. MicroRNAs (miRNAs) play vital roles in developing insect antiviral immunity. MiRNAs expression profiles of insects changed significantly during baculovirus infection. Methods: Differential expression profiles of miRNAs in Spodoptera frugiperda were monitored by next-generation sequencing (NGS) and RT-qPCR during Autographa californica multiple nucleopolyhedrovirus (AcMNPV) infection. The transcription levels of genes were detected by RT-qPCR. The 50% tissue culture infective dose (TCID50) endpoint dilution assay was used to determine the proliferation of progeny virus. Results: NGS revealed that 49 miRNAs were differentially expressed in Sf9 cells, and 10 of… More >

Reemah M. Alhebshi¹, Nauman Ahmed², Dumitru Baleanu^3,4,5, Umbreen Fatima^6,*, Fazal Dayan⁷, Muhammad Rafiq^8,9, Ali Raza¹⁰, Muhammad Ozair Ahmad², Emad E. Mahmoud¹¹

CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5663-5678, 2023, DOI:10.32604/cmc.2023.033319

Abstract Typically, a computer has infectivity as soon as it is infected. It is a reality that no antivirus programming can identify and eliminate all kinds of viruses, suggesting that infections would persevere on the Internet. To understand the dynamics of the virus propagation in a better way, a computer virus spread model with fuzzy parameters is presented in this work. It is assumed that all infected computers do not have the same contribution to the virus transmission process and each computer has a different degree of infectivity, which depends on the quantity of virus. Considering this, the parameters and being… More >

Manal. M. Alqarni¹, Arooj Nasir^2,3, Dumitru Baleanu^4,5,6, Ali Raza⁷, Tahir Nawaz Cheema^8,*, Nauman Ahmed⁹, Muhammad Rafiq¹⁰, Umbreen Fatima¹¹, Emad E. Mahmoud¹²

CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 6807-6822, 2023, DOI:10.32604/cmc.2023.033283

Abstract Artificial intelligence is demonstrated by machines, unlike the natural intelligence displayed by animals, including humans. Artificial intelligence research has been defined as the field of study of intelligent agents, which refers to any system that perceives its environment and takes actions that maximize its chance of achieving its goals. The techniques of intelligent computing solve many applications of mathematical modeling. The research work was designed via a particular method of artificial neural networks to solve the mathematical model of coronavirus. The representation of the mathematical model is made via systems of nonlinear ordinary differential equations. These differential equations are established… More >