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  • Open Access

    ARTICLE

    Enhanced Flow Boiling Heat Transfer of HFE-7100 in Open Microchannels Using Micro-Nano Composite Structures

    Liaofei Yin1,*, Kexin Zhang1, Tianjun Qin1, Wenhao Ma1, Yi Ding1, Yawei Xu2,*

    Frontiers in Heat and Mass Transfer, Vol.23, No.3, pp. 751-764, 2025, DOI:10.32604/fhmt.2025.067385 - 30 June 2025

    Abstract Flow boiling in open microchannels offers highly efficient heat transfer performance and has attracted increasing attention in the fields of heat transfer and thermal management of electronic devices in recent years. However, the continuous rise in power density of electronic components imposes more stringent requirements on the heat transfer capability of microchannel flow boiling. HFE-7100, a dielectric coolant with favorable thermophysical properties, has become a focal point of research for enhancing flow boiling performance in open microchannels. The flow boiling heat transfer performance of HFE-7100 was investigated in this study by fabricating micro-nano composite structures… More >

  • Open Access

    ARTICLE

    Partial gland ablation with high intensity focal ultrasound impact on genito-urinary function and quality of life: our initial experience

    Ioana Fugaru1, David Bouhadana1, Gautier Marcq2,3, Joseph Moryousef4, Alexis Rompré-Brodeur1, Andrew Meng4, Oleg Loutochin1, George Loutochin1, Maurice Anidjar1, Frank Bladou5, Rafael Sanchez-Salas1

    Canadian Journal of Urology, Vol.31, No.1, pp. 11784-11793, 2024

    Abstract Introduction: Partial gland ablation (PGA) using high intensity focal ultrasound (HIFU) is an alternative to active surveillance for low to intermediate risk localized prostate cancer. This pilot study assessed quality of life (QoL) outcomes during the implementation of PGA HIFU at our institution.
    Materials and methods: We prospectively enrolled 25 men with a diagnosis of localized low/intermediate risk prostate cancer who elected to undergo PGA-HIFU in a pilot study at our institution between 2013 and 2016. Patients underwent pre-treatment mpMRI and transrectal ultrasound-guided biopsies. The primary endpoints were impact on patient-reported functional outcomes (erectile, urinary function, QoL)… More >

  • Open Access

    RESIDENT’S CORNER

    Holmium laser enucleation of the prostate for a case of transition zone prostate cancer

    Michelle K. Li, Orlando Diaz, Jonathan E. Katz

    Canadian Journal of Urology, Vol.31, No.2, pp. 11861-11863, 2024

    Abstract Standard treatment approaches for localized prostate cancer remain limited to active surveillance, radiotherapy, and radical prostatectomy. We present a case of transition zone prostate cancer that was treated with holmium laser enucleation of the prostate, a procedure that is normally reserved for the management of benign prostatic hyperplasia. More >

  • Open Access

    ARTICLE

    Implications of MRI contrast enhancement following focal prostate cancer cryoablation

    James Wysock1,*, Jesse Persily1,*, Angela Tong2, Eli Rapoport1, Ben Zaslavsky1, Majlinda Tafa1, Herbert Lepor1

    Canadian Journal of Urology, Vol.31, No.5, pp. 11986-11991, 2024

    Abstract Introduction: Local disease recurrence following focal therapy (FT) for prostate cancer may be due to failure to eradicate focal disease or development of disease in the untreated prostate (in- and out-of-field recurrences). Several studies suggest in-field contrast enhancement (CE) on post treatment multi-parametric (mp) MRI between 6-12 months following FT indicates residual disease. The present study assesses the incidence and oncologic implications of early CE observed following primary partial gland cryoablation (PPGCA).
    Material and methods: The surveillance protocol for men enrolled in our prospective outcomes study following PPGCA included mpMRI at 6-12 months, 2 years, 3.5 years,… More >

  • Open Access

    REVIEW

    Surgical Ablation in Congenital Heart Disease: Advances in Techniques and Clinical Outcomes

    Manouk H. C. Linderhof1,#, Hoang H. Nguyen1,2,#, Annemien E. van den Bosch1, Mathijs S. van Schie1, Vehpi Yildirim1, Yannick J. H. J. Taverne3, Natasja M. S. de Groot1,*

    Congenital Heart Disease, Vol.19, No.6, pp. 577-592, 2024, DOI:10.32604/chd.2025.062129 - 27 January 2025

    Abstract Surgical ablation (SA) has become an essential rhythm-control strategy for managing tachyarrhythmias in patients with congenital heart disease. Atrial tachyarrhythmias, such as atrial flutter and atrial fibrillation, are prevalent in congenital heart disease, affecting up to 50% of patients, and pose significant risks, including increased morbidity and mortality. Ventricular tachyarrhythmias, though less common, can lead to sudden cardiac death, particularly in conditions like Tetralogy of Fallot. Prior studies suggested that SA for tachyarrhythmias in patients with congenital heart disease offers significant benefits, including superior long-term rhythm control compared to catheter ablation (CA). Atrial tachyarrhythmia burden… More > Graphic Abstract

    Surgical Ablation in Congenital Heart Disease: Advances in Techniques and Clinical Outcomes

  • Open Access

    ARTICLE

    GliomaCNN: An Effective Lightweight CNN Model in Assessment of Classifying Brain Tumor from Magnetic Resonance Images Using Explainable AI

    Md. Atiqur Rahman1, Mustavi Ibne Masum1, Khan Md Hasib2, M. F. Mridha3,*, Sultan Alfarhood4, Mejdl Safran4,*, Dunren Che5

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2425-2448, 2024, DOI:10.32604/cmes.2024.050760 - 08 July 2024

    Abstract Brain tumors pose a significant threat to human lives and have gained increasing attention as the tenth leading cause of global mortality. This study addresses the pressing issue of brain tumor classification using Magnetic resonance imaging (MRI). It focuses on distinguishing between Low-Grade Gliomas (LGG) and High-Grade Gliomas (HGG). LGGs are benign and typically manageable with surgical resection, while HGGs are malignant and more aggressive. The research introduces an innovative custom convolutional neural network (CNN) model, Glioma-CNN. GliomaCNN stands out as a lightweight CNN model compared to its predecessors. The research utilized the BraTS 2020 More >

  • Open Access

    ARTICLE

    Surgical treatment for BPH refractory to medication: robotic water jet ablation vs. TURP functional outcomes from two FDA clinical trials

    Alexis E. Te1, Christina Sze1, Steven A. Kaplan2, Bilal Chughtai1

    Canadian Journal of Urology, Vol.30, No.1, pp. 11408-11413, 2023

    Abstract Introduction: A common indication for benign prostate hyperplasia (BPH) therapies is failure to improve with medical therapy. However, pivotal Federal Drug Administration (FDA) registered randomized clinical trials (RCTs) for minimally invasive surgical therapies (MISTs) are designed to be compared to either sham or placebo while off medical therapy at baseline, and as an alternative to medical therapy. There are few if any RCTs reporting the MISTS efficacy in patients with true medical therapy failure. We report on the efficacy of robotic water jet ablation therapy (RWT) and TURP in patients who have failed to improve with… More >

  • Open Access

    ARTICLE

    Aquablation versus TURP: 5-year outcomes of the WATER randomized clinical trial for prostate volumes 50-80 mL

    Kussil Oumedjbeur1, Nicholas J. Corsi2, David Bouhadana3, Ahmed Ibrahim4, David-Dan Nguyen5, Imad Matta4, Adel Arezki3, Iman Sadri3, Tawfik Elsherbini6, Naeem Bhojani4, Dean S. Elterman5, Bilal Chughtai7, Brian T. Helfand8, Alexander P. Glaser8, Vincent Misrai9, Steven Kaplan10, Peter Gilling11, Neil Barber12, Mihir Desai13, Gopal H. Badlani14, Alexis E. Te7, Claus G. Roehrborn15, Kevin C. Zorn4

    Canadian Journal of Urology, Vol.30, No.5, pp. 11650-11658, 2023

    Abstract Introduction: To report the 5-year efficacy and safety of Aquablation compared with transurethral resection of the prostate for the management of lower urinary tract symptoms secondary to benign prostatic hyperplasia in men with prostate volumes 50-80 mL.
    Materials and methods: In a large double-blinded, multicenter, and prospective randomized controlled trial, 96 randomized men with 50-80 mL prostates who underwent Aquablation or transurethral prostate resection were prospectively identified for subgroup analysis. Follow up was performed for up to 5 years. The primary efficacy endpoint was the reduction in International Prostate Symptom Score (IPSS) at 6 months. The primary… More >

  • Open Access

    PROCEEDINGS

    The Coupled Thermo-Chemo-Mechanical Peridynamics for ZrB2 Ceramics Ablation Behavior

    Yuanzhe Li1, Qiwen Liu2,*, Lisheng Liu2, Hai Mei2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.1, pp. 1-1, 2023, DOI:10.32604/icces.2023.09500

    Abstract The ablation of ultra-high-temperature ceramics (UTHCs) is a complex physicochemical process including mechanical behavior, temperature effect, and chemical reactions. In order to realize the structural optimization and functional design of ultra-high temperature ceramics, a coupled thermo-chemomechanical bond-based peridynamics (PD) model is proposed based on the ZrB2 ceramics oxidation kinetics model and coupled thermomechanical bond-based peridynamics. Compared with the traditional coupled thermo-mechanical model, the proposed model considers the influence of chemical reaction process on the ablation resistance of ceramic materials. In order to verify the reliability of the proposed model, the thermomechanical coupling model, damage model and… More >

  • Open Access

    PROCEEDINGS

    A Coupled Peridynamics Model for the Ablation and Plastic Fracture Simulation of Reactor Pressure Vessels

    Yonggang Zheng1,*, Hanbo Zhang1, Jingyan Li1, Hui Li2, Hongfei Ye1, Hongwu Zhang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.1, pp. 1-2, 2023, DOI:10.32604/icces.2023.010050

    Abstract The reactor pressure vessels (RPV), a typical kind of axisymmetric structures, usually serve under high temperature and pressure conditions. The numerical analysis of the mechanical behaviors of these structures plays a dominant role for their structural design, advanced manufacture and safety assessment in practical engineering applications[1-2]. However, the extremely conditions bring great challenges for the numerical analysis of structures undergo ablation, plastic, damage and even fracture during an accident[3]. Based on the superior performance of peridynamics model in predicting fracture behaviors [4-7], a coupled axisymmetric non-ordinary state-based peridynamics (CA-NOSB-PD) model is proposed in this work… More >

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