V.B.Shim ¹, K. Mithraratne ¹

CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.3, pp. 279-294, 2014, DOI:10.32604/cmes.2014.098.279

Abstract The activation of NF-kB is an important precursor in developing melanoma. However the role of mechanical stimulation in the NF-kB activation has not been studied. We used a multiscale computational modeling approach to investigate the role of mechanical stimulation and the skin tissue internal structures in the activation of NF-kB. Our model is made up of three levels – 1) the macro level where a FE model of the Zygomaticus major muscle was developed; 2) the meso level where a micro FE model of the skin block using a sample from human cadaver was developed; 3) the cell level where… More >

Alberto M. Coronado¹, Hanchen Huang²

CMES-Computer Modeling in Engineering & Sciences, Vol.10, No.1, pp. 39-44, 2005, DOI:10.3970/cmes.2005.010.039

Abstract Nanostructure fabrication or surface processing in general is predominantly kinetics-limited. One of the kinetics factors is surface diffusion, which involves intricate interplay between the diffusing atoms and substrate atoms. On Cu{111} surfaces, both adatoms and dimers diffuse very fast. Recent studies have shown that adatoms encounter a large facet-facet barrier, even though their conventional Ehrlich-Schwoebel barriers are small. This work examines the facet-facet diffusion barriers of dimers. Our results show that a dimer prefers diffusion through atom-by-atom mechanism, having a barrier of 0.52 eV from {111} to {111} facet and a barrier of 0.55 eV from {111} to {100} facet.… More >

Sifan Long¹, Ming Zhao^2,*, Xinfu He³

CMC-Computers, Materials & Continua, Vol.58, No.3, pp. 727-760, 2019, DOI:10.32604/cmc.2019.04454

Abstract With the development of society and the exhaustion of fossil energy, researcher need to identify new alternative energy sources. Nuclear energy is a very good choice, but the key to the successful application of nuclear technology is determined primarily by the behavior of nuclear materials in reactors. Therefore, we studied the radiation performance of the fusion material reduced activation ferritic/martensitic (RAFM) steel. The main novelty of this paper are the statistical analysis of RAFM steel data sets through related statistical analysis and the formula derivation of the gradient descent method (GDM) which combines the gradient descent search strategy of the… More >