Longqi Liao¹, Jing Li², Yuhua Li³, Yuemin Wang³, Jinhua Li^1,*, Liyuan Cao^4,*, Chunxiang Li^4,*

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.072237 - 08 January 2026

Abstract Quantitative detection of sleeve grouting compactness is a technical challenge in civil engineering testing. This study explores a novel quantitative detection method based on ultrasonic time-frequency dual-domain analysis. It establishes a mapping relationship between sleeve grouting compactness and characteristic parameters. First, this study made samples with gradient defects for two types of grouting sleeves, G18 and G20. These included four cases: 2D, 4D, 6D defects (where D is the diameter of the grouting sleeve), and no-defect. Then, an ultrasonic input/output data acquisition system was established. Three-dimensional sound field distribution data were obtained through an orthogonal… More >

Wu Feng^1,2,*, Tengku Anita Raja Hussin¹, Xu Yang³

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.071664 - 08 January 2026

Abstract This study investigates the thermo–mechanical behavior of C40 concrete and reinforced concrete subjected to elevated temperatures up to 700°C by integrating experimental testing and advanced numerical modeling. A temperature-indexed Concrete Damage Plasticity (CDP) framework incorporating bond–slip effects was developed in Abaqus to capture both global stress–strain responses and localized damage evolution. Uniaxial compression tests on thermally exposed cylinders provided residual strength data and failure observations for model calibration and validation. Results demonstrated a distinct two-stage degradation regime: moderate stiffness and strength reduction up to ~400°C, followed by sharp deterioration beyond 500°C–600°C, with residual capacity at… More >

Hüseyin Bilgin^*, Bredli Plaku

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.071007 - 08 January 2026

Abstract Nonlinear static procedures are widely adopted in structural engineering practice for seismic performance assessment due to their simplicity and computational efficiency. However, their reliability depends heavily on how the nonlinear behaviour of structural components is represented. The recent earthquakes in Albania (2019) and Türkiye (2023) have underscored the need for accurate assessment techniques, particularly for older reinforced concrete buildings with poor detailing. This study quantifies the discrepancies between default and user-defined component modelling in pushover analysis of pre-modern reinforced concrete structures, analysing two representative low- and mid-rise reinforced concrete frame buildings. The lumped plasticity approach… More > Graphic Abstract

Zhengyan Chang, Weiwei Wang, Mingliang Yang, Heng Yang, Qing Dong, Keyuan Zhao, Jie Yuwen^*

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.066572 - 08 January 2026

Abstract To address the neglect of seismic performance in conventional double-girder bridge crane optimization, this paper introduces a time-history analysis-based seismic optimization methodology for crane structures. Using a 25-t nuclear power crane as a case study, a bridge frame finite element model is established and validated through static analysis, confirming its accurate representation of the physical entity’s mechanical behavior. Furthermore, with bridge mass reduction as the objective and structural strength, stiffness, stability, and seismic mechanical performance as constraints, an optimization model is developed employing the Whale Optimization Algorithm (WOA). More >

Zezhi Wen¹, Kai Zhang¹, Shanlin Liang², Liqiong Chen^1,*, Zijian Xiong¹

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.066408 - 08 January 2026

Abstract Maintaining the structural integrity of parallel natural gas pipelines during leakage-induced jet fires remains a critical engineering challenge. Existing methods often fail to account for the complex interactions among heat transfer, material behavior, and pipeline geometry, which can lead to overly simplified and potentially unsafe assessments. To address these limitations, this study develops a multiphysics approach that integrates small-orifice leakage theory with detailed thermo-fluid-structural simulations. The proposed framework contributes to a more accurate failure analysis through three main components: (1) coupled modeling that tracks transient heat flow and stress development as fire conditions evolve; (2)… More >

Lv Ling^1,#, Minying Lu^2,#, Ling Ye³, Yuanhang Chen², Sheng Lin², Jun Yang², Yu Rong^2,*, Guixiong Wu^4,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069889 - 30 December 2025

Abstract Background: A significant proportion of patients still cannot benefit from existing targeted therapies and immunotherapies, making the search for new treatment strategies extremely urgent. In this study, we combined integrate public data analysis with experimental validation to identify novel prognostic biomarkers and therapeutic targets for lung adenocarcinoma (LUAD). Methods: We analyzed RNA and protein databases to assess the expression levels of cytochrome C oxidase 5B (COX5B) in LUAD. Several computational algorithms were employed to investigate the relationship between COX5B and immune infiltration in LUAD. To further elucidate the role of COX5B in LUAD, we utilized… More > Graphic Abstract

Kun Deng^1,2,3, Jianliang Huang^1,2,3, Danyang Li^2,3, Wei Gao^2,3, Minghua Wu^2,3,4,*, Mingsheng Lei^1,5,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069442 - 30 December 2025

Abstract Background: Glioblastoma (GBM) prognosis has seen little improvement over the past two decades. While immunotherapy has revolutionized cancer treatment, its impact on GBM remains limited. To characterize the evolving research landscape and identify future directions in GBM immunotherapy, we conducted a comprehensive bibliometric review. Methods: All literature related to immunotherapy in GBM from 1999 to 2024 was collected from the Web of Science Core Collection. CtieSpace and VOSviewer were used to conduct bibliometric analysis and visualize the data. Results: Bibliometric analysis identified 5038 publications authored by 23,335 researchers from 4699 institutions across 96 countries/regions, published in… More >

Xu Guo¹, Yanan Yu², Xiaolin Ma³, Yuanjie Cai^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069274 - 30 December 2025

Abstract Background: Long non-coding RNAs (lncRNAs) act as epigenetic regulators for tumor hallmarks. This investigation sought to probe the carcinogenic trait of PAN3-AS1 across pan-cancer comprehensively. Methods: We studied the diagnostic and prognostic features and the immune landscape of PAN3-AS1 across pan-cancer by bioinformatics approaches. The hierarchical regulatory networks governing PAN3-AS1 expression in colon cancer were explored via chromatin immunoprecipitation, luciferase activity assays, and RNA immunoprecipitation, etc. We screened drugs sensitive to WAP four-disulfide core domain 13 (WFDC13) by virtual screening and molecular docking. Results: Single-cell transcriptomics demonstrated that a variety of immune populations abnormally expressed PAN3-AS1… More >

Xiaopan Zou^1,2, Meiyang Sun³, Xin Jiang¹, Jingze Yu², Xiaomeng Li^4,*, Bingyu Nie^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.066662 - 30 December 2025

Abstract Objective: Triple-negative breast cancer (TNBC) is highly aggressive and lacks an effective targeted therapy. This study aimed to elucidate the functions and possible mechanisms of action of zinc finger miz-type containing 2 (ZMIZ2) and minichromosome maintenance complex component 3 (MCM3) in TNBC progression. Methods: The relationship between ZMIZ2 expression and clinical characteristics of TNBC was investigated. In vitro and in vivo experiments were performed to investigate the role of ZMIZ2 dysregulation in TNBC cell malignant behaviors. The regulatory relationship between ZMIZ2 and MCM3 was also explored. Transcriptome sequencing was performed to elucidate possible mechanisms underlying the ZMIZ2/MCM3… More >

Marija Macenić, Tomislav Kurevija^*, Tin Herbst

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.067067 - 27 December 2025

Abstract The increased interest in geothermal energy is evident, along with the exploitation of traditional hydrothermal systems, in the growing research and projects developing around the reuse of already-drilled oil, gas, and exploration wells. The Republic of Croatia has around 4000 wells, however, due to a long period since most of these wells were drilled and completed, there is uncertainty about how many are available for retrofitting as deep-borehole heat exchangers. Nevertheless, as hydrocarbon production decreases, it is expected that the number of wells available for the revitalization and exploitation of geothermal energy will increase. The… More >