Long Chen¹, Ting Li¹, Liang Liu¹, Wenshuo Wang^2,*, Xiaoxiao Du³, Wei Wang³

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 2773-2806, 2024, DOI:10.32604/cmes.2024.046641

Abstract This study explores the implementation of computed tomography (CT) reconstruction and simulation techniques for patient-specific valves, aiming to dissect the mechanical attributes of calcified valves within transcatheter heart valve replacement (TAVR) procedures. In order to facilitate this exploration, it derives pertinent formulas for 3D multi-material isogeometric hyperelastic analysis based on Hounsfield unit (HU) values, thereby unlocking foundational capabilities for isogeometric analysis in calcified aortic valves. A series of uniaxial and biaxial tensile tests is executed to obtain an accurate constitutive model for calcified active valves. To mitigate discretization errors, methodologies for reconstructing volumetric parametric models, integrating both geometric and material… More > Graphic Abstract

Salah Alzghoul^1,*, Othman Smadi¹, Ali Al Bataineh², Mamon Hatmal³, Ahmad Alamm⁴

Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 455-470, 2023, DOI:10.32604/iasc.2023.038338

Abstract Currently, the decision of aortic valve replacement surgery time for asymptomatic patients with moderate-to-severe aortic stenosis (AS) is made by healthcare professionals based on the patient’s clinical biometric records. A delay in surgical aortic valve replacement (SAVR) can potentially affect patients’ quality of life. By using ML algorithms, this study aims to predict the optimal SAVR timing and determine the enhancement in moderate-to-severe AS patient survival following surgery. This study represents a novel approach that has the potential to improve decision-making and, ultimately, improve patient outcomes. We analyze data from 176 patients with moderate-to-severe aortic stenosis who had undergone or… More >

Supaporn Roymanee^1,*, Nantawan Su-angka^1,2, Worakan Promphan^2,3,*, Kanjarut Wongwaitaweewong¹, Jirayut Jarutach¹, Rujira Buntharikpornpun¹, Pimpak Prachasilchai^2,3

Congenital Heart Disease, Vol.18, No.2, pp. 169-181, 2023, DOI:10.32604/chd.2023.021238

Abstract Background: Ventricular septal defect (VSD) is the most common congenital heart disease. Transcatheter VSD closure is an effective treatment for patients with muscular and perimembranous VSD. However, there is a limit data for outlet VSD, especially impact to the aortic valve leaflet after transcatheter closure. This study aims to assess the outcomes of transcatheter closure of the outlet-type ventricular septal defect (OVSD) after 1 postoperative year. Methods: A retrospective study was performed including 50 patients who underwent transcatheter (n = 25) and surgical (n = 25) OVSD closure during the exact time frame at two medical centres. Results: The median age and body weight… More > Graphic Abstract

Vitaliy Suvorov^*, Vladimir Zaitsev, Nikolay Pilyugov, Olga Tereshenko, Michail Komissarov

Congenital Heart Disease, Vol.18, No.1, pp. 57-65, 2023, DOI:10.32604/chd.2023.025522

Abstract Critical aortic valve stenosis in newborns is the cause of a severe clinical condition with the onset of symptoms during first hours after birth. We present a clinical case of a successful surgical correction of a critical aortic stenosis using a hybrid method applied in a newborn during the first day of life. The infant was diagnosed with a hypoplastic left heart complex with an intact atrial septum (aortic and mitral valves stenosis variant), that led to the cardiogenic shock and acute pulmonary edema. The procedure included bilateral banding of the pulmonary artery branches and atrioseptostomy with stenting of the… More > Graphic Abstract

Pengzhu Li, Martina Bačová, Robert Dalla-Pozza, Nikolaus Alexander Haas, Felix Sebastian Oberhoffer^*

Congenital Heart Disease, Vol.17, No.2, pp. 129-141, 2022, DOI:10.32604/CHD.2022.018300

Abstract Turner syndrome (TS) is a rare disorder affecting 25–50 in 100000 female newborns. Bicuspid aortic valve (BAV) is assumed to be the most common congenital heart defect (CHD) in TS. In literature, reported BAV prevalence in TS ranges between 14% and 34%. The specific BAV prevalence in TS is still unknown. The aim of this study was to give a more precise estimation of BAV prevalence in TS by conducting a meta-analysis of TS-studies, which detected BAV by either cardiac magnetic resonance imaging (MRI) or cardiac computed tomography (CT). We searched PubMed, Cochrane Library, and Web of Science databases to… More >

Milica Karadzic Kocica¹, Hristina Ugrinovic¹, Dejan Lazovic², Nemanja Karamarkovic², Milos Grujic², Borivoje Lukic³, Oliver Radmili³, Vladimir Cvetic³, Mladen Kocica^2,*

Congenital Heart Disease, Vol.16, No.6, pp. 647-653, 2021, DOI:10.32604/CHD.2021.016923

Abstract A single coronary artery is a very rare condition, commonly associated with other congenital anomalies. It could be generally considered as neither benign nor malignant form of congenital coronary artery anomalies since its pathophysiological and clinical implications grossly depend on different anatomical patterns defined by the site of origin and distribution of the branches. By presenting the patient who underwent successful coronary artery bypass grafting and aortic valve replacement surgery in a presence of isolated single coronary artery, we intend to emphasize natural and procedural risks and distinguish casual from causal in this extremely rare clinical and surgical scenario. More >

Laura Schweikert¹, Dominik Gabbert¹, Sylvia Krupickova², Inga Voges^1,*

Congenital Heart Disease, Vol.16, No.6, pp. 551-560, 2021, DOI:10.32604/CHD.2021.016635

Abstract Background: An isolated bicuspid aortic valve (BAV) is associated with structural and functional abnormalities of the aorta and the left ventricle (LV). Although ~50% of patients with aortic coarctation (CoA) have a BAV, less is known about its impact on LV function and aortic geometry and function in CoA patients. In this cardiovascular magnetic resonance imaging (CMR) study, we analysed markers of LV and aortic function as well as aortic geometry in a large cohort of CoA patients with a BAV and compared them with CoA patients with a tricuspid aortic valve (TAV). Methods: We included 48 patients with a… More >

Wenqian Zhang^1,2,#, Chaojie Wang^1,3,#, Lingmei Zhou^2,4,#, Junjie Li², Jijun Shi², Yumei Xie², Mingyang Qian², Shushui Wang², Zhiwei Zhang^1,2,*

Congenital Heart Disease, Vol.16, No.5, pp. 519-528, 2021, DOI:10.32604/CHD.2021.015527

Abstract Objective: This study aims to evaluate the morphology and function of the aortic valve after transcatheter closure of ventricular septal defect (VSD) with aortic valve prolapse (AVP) abased on clinical and radiological outcomes. Methods: From January 2013 to November 2014, 164 consecutive patients (97 males, 59.1%) with VSD and AVP were treated by transcatheter closure. The patients were divided into the mild AVP group (n = 63), moderate AVP group (n = 89) and severe AVP group (n = 12). The clinical and radiological outcomes of these patients were analyzed retrospectively. Results: In total, 146 (89.0%) patients were successfully treated… More >

Adi Azriff Basri^1,6,*, Mohammad Zuber², Ernnie Illyani Basri¹, Muhammad Shukri Zakaria⁵, Ahmad Fazli Abd Aziz³, Masaaki Tamagawa⁴, Kamarul Arifin Ahmad^1,6

FDMP-Fluid Dynamics & Materials Processing, Vol.17, No.3, pp. 531-553, 2021, DOI:10.32604/fdmp.2021.010925

Abstract Paravalvular Leakage (PVL) has been recognized as one of the most dangerous complications in relation to Transcathether Aortic Valve Implantation (TAVI) activities. However, data available in the literature about Fluid Structure Interaction (FSI) for this specific problem are relatively limited. In the present study, the fluid and structure responses of the hemodynamics along the patient aorta model and the aortic wall deformation are studied with the aid of numerical simulation taking into account PVL and 100% TAVI valve opening. In particular, the aorta without valve (AWoV) is assumed as the normal condition, whereas an aorta with TAVI 26 mm for… More >

Caili Li¹, Dalin Tang^2,*,3, Jing Yao^4,*, Christopher Baird⁵, Haoliang Sun⁶, Chanjuan Gong⁷, Luyao Ma⁶, Yanjuan Zhang⁴, Liang Wang², Han Yu², Chun Yang⁸, Yongfeng Shao⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.127, No.1, pp. 159-174, 2021, DOI:10.32604/cmes.2021.014580

Abstract Aortic valve replacement (AVR) remains a major treatment option for patients with severe aortic valve disease. Clinical outcome of AVR is strongly dependent on implanted prosthetic valve size. Fluid-structure interaction (FSI) aortic root models were constructed to investigate the effect of valve size on hemodynamics of the implanted bioprosthetic valve and optimize the outcome of AVR surgery. FSI models with 4 sizes of bioprosthetic valves (19 (No. 19), 21 (No. 21), 23 (No. 23) and 25 mm (No. 25)) were constructed. Left ventricle outflow track flow data from one patient was collected and used as model flow conditions. Anisotropic Mooney–Rivlin… More >