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  • Open Access

    ARTICLE

    The Identification of Elastic Moduli of a Stratified Layer Through Localized Surface Probes, with Biomedical Applications

    A.R.Skovoroda1, R.V.Goldstein2

    CMES-Computer Modeling in Engineering & Sciences, Vol.4, No.3&4, pp. 457-472, 2003, DOI:10.3970/cmes.2003.004.457

    Abstract We discuss the inverse problem of the recovery of the distribution of the elastic moduli of a stratified layer, based on measurements of the surface displacement under localized surface loads. A general parametric solution and a numerical procedure for computing the parameters are presented. Examples of numerical results are given. The problem and its solution are related to the monitoring of elastic properties of living tissues. More >

  • Open Access

    ABSTRACT

    A study of surface force on self-assembled monolayer of bio-microchannel

    J.H. Horng1, C.C. Wei1, Y.L. Ye2, C.H. Huang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.15, No.1, pp. 9-18, 2010, DOI:10.3970/icces.2010.015.009

    Abstract In this paper, four kinds of biocompatible SAMs are used to improve adhesion property and fluorescence reaction property on specimen surfaces. The result of experiment shows that OTS film demonstrates contact angles are all larger than 100 degrees in different immersing time and it reveal the best hydrophobic property after 24 hours. The declination angle experiment demonstrates that the OTS film has best flowing property and same trend of friction coefficient; it indicates that the declination angle experiment can reveal the degree of microchannel adhesion property better than contact angle experiment. It can be found that the OTS film can… More >

  • Open Access

    ARTICLE

    Structural Refinement of Titanium-Aluminum-Niobium Alloy for Biomedical Applications

    Joaquín E. González-Hernández1, Jorge M. Cubero-Sesin1,2*, Elena Ulate-Kolitsky1, Priscilla Navarro1, Stephen Petretti1, Zenji Horita3,4

    Journal of Renewable Materials, Vol.5, No.3-4, pp. 300-306, 2017, DOI:10.7569/JRM.2017.634120

    Abstract In this work, a modification of the microstructure of a commercial Ti-6Al-7Nb alloy was accomplished by high-pressure torsion (HPT) at room temperature, to produce a bulk nanostructure on discs of 10 mm diameter and ~0.8 mm thickness. The metallographic analyses of the discs were performed by optical microscopy and scanning electron microscopy with energy dispersive spectroscopy. The results confirmed the presence of aluminum (Al) and niobium (Nb) as the sole alloying elements, promoting a duplex (α + β) titanium (Ti) microstructure prior to HPT processing. After HPT processing, nanostructure refinement was attained, reflected in the X-ray diffraction profiles as broadening… More >

  • Open Access

    ARTICLE

    Functional Electrospun Poly (Lactic Acid) Scaffolds for Biomedical Applications: Experimental Conditions, Degradation and Biocompatibility Study

    Idalba A. Hidalgo A., Felipe Sojo, Francisco Arvelo, Marcos A. Sabino∗,‡

    Molecular & Cellular Biomechanics, Vol.10, No.2, pp. 85-105, 2013, DOI:10.3970/mcb.2013.010.085

    Abstract The electrospinning technique is a method used to produce nano and microfibers using the influence of electrostatic forces. Porous three dimensional networks of continuous and interconnected fibers as scaffolds were obtained from a poly (lactic acid) solution. The concentration of the polymeric solution, 12.5% m/w, as well as the conditions of voltage (V=11kV) and tip-metallic collector distance (H=13cm) were established to develop these scaffolds through the electrospinning process. The characteristics of the scaffolds, such as fiber diameter, sintering and the biomimetics of the characteristics of a native extra cellular matrix were verified by Scanning Electron Microscopy (SEM). The orientation induced… More >

  • Open Access

    ARTICLE

    Parkinson’s Disease Detection Using Biogeography-Based Optimization

    Somayeh Hessam1, Shaghayegh Vahdat1, Irvan Masoudi Asl2,*, Mahnaz Kazemipoor3, Atefeh Aghaei4, Shahaboddin Shamshirband,5,6,*, Timon Rabczuk7

    CMC-Computers, Materials & Continua, Vol.61, No.1, pp. 11-26, 2019, DOI:10.32604/cmc.2019.06472

    Abstract In recent years, Parkinson's Disease (PD) as a progressive syndrome of the nervous system has become highly prevalent worldwide. In this study, a novel hybrid technique established by integrating a Multi-layer Perceptron Neural Network (MLP) with the Biogeography-based Optimization (BBO) to classify PD based on a series of biomedical voice measurements. BBO is employed to determine the optimal MLP parameters and boost prediction accuracy. The inputs comprised of 22 biomedical voice measurements. The proposed approach detects two PD statuses: 0-disease status and 1- good control status. The performance of proposed methods compared with PSO, GA, ACO and ES method. The… More >

  • Open Access

    ARTICLE

    Bus Encoded LUT Multiplier for Portable Biomedical Therapeutic Devices

    R. Praveena1, S. Nirmala2

    CMC-Computers, Materials & Continua, Vol.53, No.1, pp. 37-47, 2017, DOI:10.3970/cmc.2017.053.039

    Abstract DSP operation in a Biomedical related therapeutic hardware need to be performed with high accuracy and with high speed. Portable DSP hardware’s like pulse/heart beat detectors must perform with reduced operational power due to lack of conventional power sources. This work proposes a hybrid biomedical hardware chip in which the speed and power utilization factors are greatly improved. Multipliers are the core operational unit of any DSP SoC. This work proposes a LUT based unsigned multiplication which is proven to be efficient in terms of high operating speed. For n bit input multiplication n*n memory array of 2n bit size… More >

  • Open Access

    ARTICLE

    Soft Computing for Terahertz Metamaterial Absorber Design for Biomedical Application

    Balamati Choudhury1, Pavani Vijay Reddy1, Sanjana Bisoyi1, R. M. Jha1

    CMC-Computers, Materials & Continua, Vol.37, No.3, pp. 135-146, 2013, DOI:10.3970/cmc.2013.037.135

    Abstract The terahertz region of the electromagnetic spectrum plays a vital role in biomedical imaging because of its sensitivity to vibrational modes of biomolecules. Advances in broadband terahertz imaging have been emerging in the field of biomedical spectroscopy. Biomedical imaging is used to distinguish between the infected (cancer) and the non-infected tissue, which requires broad band and highly efficient radar absorbing material (RAM) designs (to obtain high resolution image of the tissue). In this paper, a metamaterial broadband RAM design is proposed towards biomedical spectroscopy applications in the THz region. The particle swarm optimization (PSO) algorithm is used for the design… More >

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