Koert de Waal1, Nilkant Phad1, Nick Collins2, Andrew Boyle2
Congenital Heart Disease, Vol.12, No.3, pp. 364-372, 2017, DOI:10.1111/chd.12454
Abstract Background: Sustained volume load due to a patent ductus arteriosus (PDA) leads to cardiac
remodeling. Remodeling changes can become pathological and are associated with cardiovascular
disease progression. Data on remodeling changes in preterm infants is not available.
Methods: Clinical and echocardiography data were collected in preterm infants <30 weeks gestation on postnatal day 3 and then every 7–14 days until closure of the ductus arteriosus. Images
were analyzed using conventional techniques and speckle tracking. Remodeling changes of infants
with prolonged (>14 days) exposure to a PDA were compared to control infants without a PDA.
Results: Thirty out of 189 infants… More >
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