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    Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6-year single-center Italian experience follow-up

    Alberto Cresti1, Raffaele Giordano2, Martin Koestenberger3, Isabella Spadoni4, Marco Scalese5, Ugo Limbruno1, Susanna Falorini6, Stefania Stefanelli1, Andrea Picchi1, Francesco De Sensi1, Angela Malandrino7, Massimiliano Cantinotti4,5

    Congenital Heart Disease, Vol.13, No.1, pp. 105-112, 2018, DOI:10.1111/chd.12528

    Abstract Background: Despite ventricular septal defects (VSDs) are the most common congenital heart diseases (CHDs) in the neonatal period, their incidence and natural history are still debated and their follow-up and management strategies remain controversial. Our aim was to evaluate the incidence and natural history of isolated VSDs.
    Methods: From January 1996 to December 2015 all neonates with a CHD suspicion were referred to the Cardiological Department of Grosseto Misericordia Hospital. Only newborns with confirmed isolated VSD were enrolled in this study and followed for 6 years.
    Results: Our 343 newborns with an isolated VSD (incidence of 10.45/1000/births) account for 64%… More >

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