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  • Open Access

    ARTICLE

    CycleGAN-RRW: Blind Reversible Image Watermarking via Cycle-Consistent Adversarial Feature Encoding for Secure Image Ownership Authentication

    Mohammed Shamar Yadkar1, Sefer Kurnaz1, Saadaldeen Rashid Ahmed2,3,*

    CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.079408 - 09 April 2026

    Abstract This advanced research describes CycleGAN-RRW, a new reversible watermarking system for secure image ownership authentication. It uses Cycle-Consistent Generative Adversarial Networks with adaptive feature encoding. In areas such as law, forensics, and telemedicine, digital images usually contain private info that may be changed or used without authorization. Existing watermarking methods may decrease image quality, may not be reversible, or need outside keys. To address these problems, our model embeds metadata into intermediate feature maps with Adaptive Instance Normalization (AdaIN), based on adversarial and perceptual loss. The dual-generator design permits two-way translation between original and watermarked… More >

  • Open Access

    ARTICLE

    Integrated WGCNA and Experimental Validation Reveals LINC00595 as Necroptosis-Regulating lncRNAs in Prostate Cancer

    Kai Tang1, Shengxing Lu1, Cuie He2, Ruozeng Rong1,*

    BIOCELL, Vol.50, No.3, 2026, DOI:10.32604/biocell.2026.072154 - 23 March 2026

    Abstract Objectives: Prostate cancer (PCa) is a highly prevalent male malignancy with limited efficacy in advanced stages. Dysregulated modulation of necroptosis was reported to be tightly correlated with PCa initiation and progression. Herein, we aimed to identify necroptosis-associated long non-coding RNAs (lncRNAs) and delineate their functional roles in PCa through an integrated approach combining bioinformatic analyses and in vitro experimental validation. Methods: RNA sequencing data and corresponding clinical information of PCa were downloaded from The Cancer Genome Atlas (TCGA). Differentially expressed necroptosis-related genes (NRGs) and lncRNAs were screened, and necroptosis activity was assessed by single-sample gene set… More >

  • Open Access

    RETRACTION

    Retraction: Long Noncoding RNA (lncRNA) HOTAIR Affects Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer by Upregulating miR-613

    Oncology Research Editorial Office

    Oncology Research, Vol.34, No.3, 2026, DOI:10.32604/or.2026.080056 - 24 February 2026

    Abstract This article has no abstract. More >

  • Open Access

    RETRACTION

    Retraction: Long Noncoding RNA PVT1 Promotes Melanoma Progression via Endogenous Sponging miR-26b

    Oncology Research Editorial Office

    Oncology Research, Vol.34, No.3, 2026, DOI:10.32604/or.2026.080055 - 24 February 2026

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    How Do LncRNAs Talk to miRNAs? Decoding Their Dialogue in Atherosclerosis

    Yating Wei1, Hongkang Yao1, Xian Shi2, Hong Chen3, Rongzong Ye4,*, Chaoqian Li1,*

    BIOCELL, Vol.50, No.2, 2026, DOI:10.32604/biocell.2025.072780 - 14 February 2026

    Abstract Atherosclerosis, characterized by the formation of fibrofatty lesions in the arterial wall, remains a leading cause of global morbidity and mortality. Emerging evidence highlights the critical regulatory roles of long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) in atherogenesis. LncRNAs can function as competing endogenous RNAs (ceRNAs) by sponging miRNAs, thereby modulating the expression of downstream target mRNAs. This review summarizes current knowledge on lncRNA-miRNA-mRNA regulatory networks and their functional roles in the three major cell types involved in atherosclerotic plaque development: endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and macrophages. In ECs, these networks More >

  • Open Access

    ARTICLE

    A Fine-Grained Recognition Model based on Discriminative Region Localization and Efficient Second-Order Feature Encoding

    Xiaorui Zhang1,2,*, Yingying Wang2, Wei Sun3, Shiyu Zhou2, Haoming Zhang4, Pengpai Wang1

    CMC-Computers, Materials & Continua, Vol.87, No.1, 2026, DOI:10.32604/cmc.2025.072626 - 10 February 2026

    Abstract Discriminative region localization and efficient feature encoding are crucial for fine-grained object recognition. However, existing data augmentation methods struggle to accurately locate discriminative regions in complex backgrounds, small target objects, and limited training data, leading to poor recognition. Fine-grained images exhibit “small inter-class differences,” and while second-order feature encoding enhances discrimination, it often requires dual Convolutional Neural Networks (CNN), increasing training time and complexity. This study proposes a model integrating discriminative region localization and efficient second-order feature encoding. By ranking feature map channels via a fully connected layer, it selects high-importance channels to generate an More >

  • Open Access

    ARTICLE

    Integrative Analysis of Genetic-Ecological Factors Shaping Epimedium Chemical Diversity

    Ziying Huang1, Ruikang Ma1, Anning Li2, Yufei Cheng1, Xiaolin Lin2, Mengzhi Li3, Yu Zhang2, Liping Shi1, Linlin Dong1,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2025.074419 - 30 January 2026

    Abstract Epimedium is commonly used to treat bone injury and kidney disease, with prenylated flavonol glycosides (PFGs) as its active ingredients. It has attracted much attention due to prominent healthcare and therapeutic effects, but faces problems of adulteration with closely related species and confusion about geographical origins. In this study, multiple technical approaches were employed to identify its genetic characteristics and metabolic differences. Based on DNA barcoding, 20 batches of samples were analyzed. The genetic distances of matK, ITS and psbA-trnH within species were all smaller than those between species, and psbA-trnH along with ITS + psbA-trnH proved most effective… More >

  • Open Access

    ARTICLE

    Development and Assessment of a Novel Palmitoylation-Related lncRNA Signature for Prognosis and Immune Landscape in Hepatocellular Carcinoma

    Zhilong He1,#, Jing Qin1,#, Sixuan Wu2,#, Xian Liang1, Yu Liu1, Jinfeng Qiu1, Zhimin Li2,*, Kai Hu1,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.070567 - 19 January 2026

    Abstract Objective: The contribution of long non-coding RNAs (lncRNAs) associated with protein palmitoylation to the progression of hepatocellular carcinoma (HCC) remains largely unclear. This study sought to establish a prognostic signature based on palmitoylation-related lncRNAs and explore their functional implications in HCC. Methods: RNA sequencing and clinical data for HCC and normal tissues were sourced from the Cancer Genome Atlas (TCGA). Pearson correlation analysis was used to identify lncRNAs that were co-expressed with palmitoylation-related genes. Univariate Cox regression was applied to select lncRNAs with prognostic value, followed by the construction of a predictive model using the… More >

  • Open Access

    REVIEW

    RP11-Derived Long Non-Coding RNAs in Hepatocellular Carcinoma: Hidden Treasures in Plain Sight

    Se Ha Jang1,2,#, Hyung Seok Kim3,#, Jung Woo Eun1,*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.072240 - 30 December 2025

    Abstract Hepatocellular carcinoma (HCC) remains one of the most prevalent and lethal malignancies worldwide. Long non-coding RNAs (lncRNAs) have emerged as crucial regulators of gene expression and cancer progression, yet the functional diversity of RP11-derived lncRNAs—originally mapped to bacterial artificial chromosome (BAC) clones from the Roswell Park Cancer Institute—has only recently begun to be appreciated. This mini-review aims to systematically synthesize current findings on RP11-derived lncRNAs in HCC, outlining their genomic origins, molecular mechanisms, and biological significance. We highlight their roles in metabolic reprogramming, microRNA network modulation, and tumor progression, as well as their diagnostic and More >

  • Open Access

    ARTICLE

    Cognitive Erasure-Coded Data Update and Repair for Mitigating I/O Overhead

    Bing Wei, Ming Zhong, Qian Chen, Yi Wu*, Yubin Li

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-20, 2026, DOI:10.32604/cmc.2025.069910 - 09 December 2025

    Abstract In erasure-coded storage systems, updating data requires parity maintenance, which often leads to significant I/O amplification due to “write-after-read” operations. Furthermore, scattered parity placement increases disk seek overhead during repair, resulting in degraded system performance. To address these challenges, this paper proposes a Cognitive Update and Repair Method (CURM) that leverages machine learning to classify files into write-only, read-only, and read-write categories, enabling tailored update and repair strategies. For write-only and read-write files, CURM employs a data-difference mechanism combined with fine-grained I/O scheduling to minimize redundant read operations and mitigate I/O amplification. For read-write files,… More >

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