Chih-Yin Chien^1,2, Tsae-Jyy Wang¹, Pei-Hung Liao¹, Ying-Hsiang Lee^3,4,5,*, Wei-Sho Ho^6,7,*

Congenital Heart Disease, Vol.20, No.5, pp. 601-612, 2025, DOI:10.32604/chd.2025.072431 - 30 November 2025

Abstract Background: Cardiac implantable electronic devices (CIEDs) are essential for preventing sudden cardiac death in patients with cardiovascular diseases, but implantation procedures carry risks of complications such as infection, hematoma, and bleeding, with incidence rates of 3–4%. Previous studies have examined individual risk factors separately, but integrated predictive models are lacking. We compared the predictive performance and interpretability of artificial neural network (ANN) and logistic regression models to evaluate their respective strengths in clinical risk assessment. Methods: This retrospective study analyzed data from 180 patients who underwent cardiac implantable electronic device (CIED) implantation in Taiwan between 2017… More >

Raidizon Mercedes, Eric Eidelman, Michael Mawhorter, Max Yudovich, Alireza Aminsharifi^*

Canadian Journal of Urology, Vol.32, No.5, pp. 515-520, 2025, DOI:10.32604/cju.2025.067973 - 30 October 2025

Abstract Background: Spontaneous rupture of the urinary bladder (SRUB) is a rare condition characterized by bladder rupture without any trauma or previous instrumentation. Diagnosing SRUB can be challenging, leading to potential delays in treatment and significant morbidity. Case description: We present a case of a 75-year-old male with a complex medical history, including atrial fibrillation, systemic lupus erythematosus, antiphospholipid syndrome, and chronic anticoagulation, who developed sudden onset gross hematuria and abdominal pain following bilateral internal iliac artery angioembolization for a spontaneous pelvic hematoma in the setting of supratherapeutic anticoagulation. Extraperitoneal bladder perforation was confirmed by CT cystogram.… More >

Ryan Daigle¹, Ilene Staff², Joseph Tortora², Tara McLaughlin Proto^3,*, Kevin Pinto³, Rosa Negron², Jonathan Earle⁴, Joseph Wagner,³

Canadian Journal of Urology, Vol.32, No.3, pp. 189-198, 2025, DOI:10.32604/cju.2025.063773 - 27 June 2025

Abstract Introduction: We examined the pathology and safety outcomes associated with the extent of pelvic lymph node dissection in patients with high-risk prostate cancer undergoing radical prostatectomy. Materials and Methods: We retrospectively identified men with prostate cancer who underwent robot-assisted radical prostatectomy with pelvic lymph node dissection between May 2016 and September 2021. Cases were categorized using Current Procedural Terminology (CPT) codes (38571) for extended lymph node dissection and super-extended lymph node dissection (38572). Using logistic regression, we compared the groups on a number of factors, including recurrence. Results: Super-extended lymph node dissection had significantly higher median… More >

Hayatu Uma^1,*, Abdulaziz Aminu¹, Raghu Cherukupalli², Femi Akindotun Akintomide¹, Abdul Habu³, Aisha Aminu Lawal¹, Adamu Mohammad¹

Congenital Heart Disease, Vol.19, No.6, pp. 635-645, 2024, DOI:10.32604/chd.2025.056641 - 27 January 2025

Abstract Laubry-Pezzi syndrome (L-PS) is a rare congenital heart disease characterized by a ventricular septal defect (VSD) and aortic valve prolapse. These cardiac lesions predispose individuals to infective endocarditis (IE), a life-threatening complication, especially in resource-constrained settings. A 17-year-old male presented with a three-week history of fever and headache, and a one-week history of abdominal pain, vomiting, and diarrhea. On presentation, he appeared toxic, was febrile, tachypneic, tachycardic, and blood pressure of 120/30 mmHg, and heart sounds were S1, S2. Abdominal examination revealed generalized tenderness. A provisional diagnosis of typhoid sepsis with intestinal perforation was considered.… More >

Jonathan S. Taylor-Fishwick^1,*, Nicholas Holzemer², Brandon Middlemist³, Vivian Duarte³, Kaitlin E. Olson⁴, Johannes C. von Alvensleben⁵, Megan SooHoo⁶, Amber Khanna⁷

Congenital Heart Disease, Vol.19, No.5, pp. 457-472, 2024, DOI:10.32604/chd.2024.057151 - 31 December 2024

Abstract Background: Post-operative atrial fibrillation (POAF) frequently occurs after cardiac surgery. Although adult congenital heart disease (ACHD) patients have higher rates of arrhythmia than the general population, there is scant literature on POAF in ACHD patients. Objectives: Identify key risk factors associated with post-operative atrial fibrillation and evaluate the short- and mid-term significance of developing POAF. Methods: A retrospective cohort study was conducted of ACHD patients from 2013–2021 at the University of Colorado Hospital and Children’s Hospital of Colorado. The institutional Society of Thoracic Surgeons (STS) surgical registry was used to identify patients ≥18-year-old with congenital heart… More >

David-Dan Nguyen^1,*, Massine Fellouah^2,*, Anna-Lisa V. Nguyen³, David-Christian Kazu⁴, Isabel Baltzan⁵, Muhieddine Labban⁶, Shubha De⁷, Kevin C. Zorn⁸, Bilal Chughtai⁹, Dean S. Elterman¹, Quoc-Dien Trinh⁶, Naeem Bhojani⁸

Canadian Journal of Urology, Vol.30, No.3, pp. 11546-11550, 2023

Abstract Introduction: 5α-reductase inhibitors (5ARI) are commonly prescribed medications. There is ongoing controversy about the adverse events of these medications. The aim of this study is to characterize lawsuits in Canada involving medical complications of 5ARIs use.
Materials and methods: Legal cases were queried from CanLII. Cases were included if they involved a party taking a 5ARI who alleged an adverse event. Relevant full cases were retained, and pertinent characteristics were extracted with the help of a legal expert.
Results: Our deduplicated search yielded 67 unique legal documents from December 2013 to February 2019. Twelve of these documents met… More >

HANY M. ABD EL-LATEEF^1,2,*, SAFA H. QAHL³, EMAN FAYAD⁴, SARAH A. ALTALHI⁴, IBRAHIM JAFRI⁴, EL SHAIMAA SHABANA⁵, MARWA K. DARWISH^6,7, REHAB MAHER⁸, SAAD SHAABAN^1,9, SHADY G. EL-SAWAH^10,*

BIOCELL, Vol.47, No.8, pp. 1885-1895, 2023, DOI:10.32604/biocell.2023.030680 - 28 August 2023

Abstract Background: The increasing occurrence of diabetes mellitus (DM) noted worldwide has considerably elicited concern in the recent past. DM is associated with elevated vascular complications, morbidity, mortality, and poor quality of life. In this context, mesenchymal stem cells (MSCs) have shown significant therapeutic potentialities in managing and curing type 1 DM owing to their self-renewable, immunosuppressive, and differentiation capacities. We investigated the potential action of N, N′-diphenyl-1,4-phenylenediamine (DPPD), a well-known synthetic antioxidant to enhance the therapeutic ability of the adipose-derived stem cells (AD-MSCs) in alleviating kidney and liver complications in diabetic rats. Methods: Over the… More > Graphic Abstract

Xingbang Li^1,#, Xuan Zheng^2,#, Bowen Jin¹, Yunyan Li¹, Yongyu Shao¹, Xiaoxian Deng¹, Dingyang Li¹, Shanshan Li¹, Hongmei Zhou¹, Jie Zhang³, Xianya Zhang⁴, Qunshan Shen¹, Gangcheng Zhang^2,*

Congenital Heart Disease, Vol.18, No.3, pp. 373-385, 2023, DOI:10.32604/chd.2023.028979 - 09 June 2023

Abstract Background: Transcatheter closure of patent foramen ovale (PFO) has been widely accepted as a highly effective way to treat high-risk PFO-related diseases. However, traditional non-degradable occluders made of metal alloys will permanently exist in the body, resulting in thrombosis, valve damage, hemolysis, arrhythmia, or other complications. The biodegradable PFO occluder developed by Shanghai Mallow Medical Instrument Co., Ltd., China can be fully absorbed and degrade into nontoxic ingredients, reducing postoperative complications. Objectives: To study the safety and efficacy of biodegradable PFO occluders in treating PFO. Methods: This single-center clinical trial collected 30 patients treated with a More > Graphic Abstract

Seth L. Teplitsky¹, Patrick J. Hensley¹, Amber Bettis², Andrew James¹, Andrew M. Harris^1,3

Canadian Journal of Urology, Vol.29, No.2, pp. 11087-11097, 2022

Abstract Introduction: To elucidate the association between operative duration (OD) and postoperative complications, which has been poorly studied in radical cystectomy. We hypothesize an increase in morbidity in radical cystectomy cases which have a longer OD.
Materials and methods: Data from the National Surgical Quality Improvement Program (NSQIP) between the years 2012 and 2018 were reviewed for radical cystectomy with ileal conduit urinary diversion or continent diversion. Total operative time was divided into deciles and stratified comparisons were made using univariable and multivariable analysis.
Results: A total of 11,128 patients were examined. OD by minutes was stratified into the… More >

Hye Won Kwon^1,2, Mi Kyoung Song¹, Sang Yun Lee¹, Gi Beom Kim¹, Sungkyu Cho², Jae Gun Kwak², Woong-Han Kim², Whal Lee³, Eun Jung Bae^1,*

Congenital Heart Disease, Vol.17, No.3, pp. 281-295, 2022, DOI:10.32604/chd.2022.019065 - 03 May 2022

Abstract Background: Mechanisms and clinical manifestations of coronary artery complications after right ventricular outflow tract reconstruction surgery are not well known. Methods: Patients who had coronary artery complications after pulmonary valve replacement or the Rastelli procedure at a single tertiary centre were retrospectively analysed. Results: Coronary artery complications were identified in 20 patients who underwent right ventricular outflow tract reconstruction surgery. The median age at diagnosis of coronary artery complication was 21 years (interquartile range: 13–25 years). Mechanisms of coronary artery complications were compression by adjacent materials in 12 patients, dynamic compression of intramural course of coronary artery… More >