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  • Open Access

    ARTICLE

    Novel Computer-Aided Diagnosis System for the Early Detection of Alzheimer’s Disease

    Meshal Alharbi, Shabana R. Ziyad*

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5483-5505, 2023, DOI:10.32604/cmc.2023.032341

    Abstract Aging is a natural process that leads to debility, disease, and dependency. Alzheimer’s disease (AD) causes degeneration of the brain cells leading to cognitive decline and memory loss, as well as dependence on others to fulfill basic daily needs. AD is the major cause of dementia. Computer-aided diagnosis (CADx) tools aid medical practitioners in accurately identifying diseases such as AD in patients. This study aimed to develop a CADx tool for the early detection of AD using the Intelligent Water Drop (IWD) algorithm and the Random Forest (RF) classifier. The IWD algorithm an efficient feature selection method, was used to… More >

  • Open Access

    ARTICLE

    Transfer Learning-based Computer-aided Diagnosis System for Predicting Grades of Diabetic Retinopathy

    Qaisar Abbas1,*, Mostafa E. A. Ibrahim1,2, Abdul Rauf Baig1

    CMC-Computers, Materials & Continua, Vol.71, No.3, pp. 4573-4590, 2022, DOI:10.32604/cmc.2022.023670

    Abstract Diabetic retinopathy (DR) diagnosis through digital fundus images requires clinical experts to recognize the presence and importance of many intricate features. This task is very difficult for ophthalmologists and time-consuming. Therefore, many computer-aided diagnosis (CAD) systems were developed to automate this screening process of DR. In this paper, a CAD-DR system is proposed based on preprocessing and a pre-train transfer learning-based convolutional neural network (PCNN) to recognize the five stages of DR through retinal fundus images. To develop this CAD-DR system, a preprocessing step is performed in a perceptual-oriented color space to enhance the DR-related lesions and then a standard… More >

  • Open Access

    REVIEW

    Detection and Grading of Diabetic Retinopathy in Retinal Images Using Deep Intelligent Systems: A Comprehensive Review

    H. Asha Gnana Priya1, J. Anitha1, Daniela Elena Popescu2, Anju Asokan1, D. Jude Hemanth1, Le Hoang Son3,4,*

    CMC-Computers, Materials & Continua, Vol.66, No.3, pp. 2771-2786, 2021, DOI:10.32604/cmc.2021.012907

    Abstract Diabetic Retinopathy (DR) is an eye disease that mainly affects people with diabetes. People affected by DR start losing their vision from an early stage even though the symptoms are identified only at the later stage. Once the vision is lost, it cannot be regained but can be prevented from causing any further damage. Early diagnosis of DR is required for preventing vision loss, for which a trained ophthalmologist is required. The clinical practice is time-consuming and is not much successful in identifying DR at early stages. Hence, Computer-Aided Diagnosis (CAD) system is a suitable alternative for screening and grading… More >

  • Open Access

    ARTICLE

    An Optimal Deep Learning Based Computer-Aided Diagnosis System for Diabetic Retinopathy

    Phong Thanh Nguyen1, Vy Dang Bich Huynh2, Khoa Dang Vo1, Phuong Thanh Phan1, Eunmok Yang3,*, Gyanendra Prasad Joshi4

    CMC-Computers, Materials & Continua, Vol.66, No.3, pp. 2815-2830, 2021, DOI:10.32604/cmc.2021.012315

    Abstract Diabetic Retinopathy (DR) is a significant blinding disease that poses serious threat to human vision rapidly. Classification and severity grading of DR are difficult processes to accomplish. Traditionally, it depends on ophthalmoscopically-visible symptoms of growing severity, which is then ranked in a stepwise scale from no retinopathy to various levels of DR severity. This paper presents an ensemble of Orthogonal Learning Particle Swarm Optimization (OPSO) algorithm-based Convolutional Neural Network (CNN) Model EOPSO-CNN in order to perform DR detection and grading. The proposed EOPSO-CNN model involves three main processes such as preprocessing, feature extraction, and classification. The proposed model initially involves… More >

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