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    The Effect of Continued Training with Crocin on Apoptosis Markers in Liver Tissue of High Fat Diet Induced Diabetic Rats

    Zahra Alimanesh1, Zeynab Alimanesh1, Fatemeh Davari2, Saeedeh Shadmehri3, Mozhgan Ahmadi3, Seyed Ali Hosseini4, Sepideh Dolati5,*, Alemeh Hariri Far6

    Molecular & Cellular Biomechanics, Vol.17, No.4, pp. 155-163, 2020, DOI:10.32604/mcb.2020.011532

    Abstract Diabetes mellitus (DM) disease can affect process of apoptosis by increasing oxidative stress, nevertheless exercise and crocin can improve apoptosis; therefore present study aimed to investigate the effect of continued training with crocin on apoptosis markers in liver tissue of diabetic rats. In this experimental study 32 diabetic rats based on fasting glucose divided into four groups of eight rats including: 1) sham, 2) training, 3) crocin, and 4) training with crocin also for investigate the effect of DM induction on apoptosis markers, eight healthy rats assigned in healthy control group. During eight weeks groups… More >

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