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  • Open Access

    ARTICLE

    Recurrent MAPPO for Joint UAV Trajectory and Traffic Offloading in Space-Air-Ground Integrated Networks

    Zheyuan Jia, Fenglin Jin*, Jun Xie, Yuan He

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-15, 2026, DOI:10.32604/cmc.2025.069128 - 10 November 2025

    Abstract This paper investigates the traffic offloading optimization challenge in Space-Air-Ground Integrated Networks (SAGIN) through a novel Recursive Multi-Agent Proximal Policy Optimization (RMAPPO) algorithm. The exponential growth of mobile devices and data traffic has substantially increased network congestion, particularly in urban areas and regions with limited terrestrial infrastructure. Our approach jointly optimizes unmanned aerial vehicle (UAV) trajectories and satellite-assisted offloading strategies to simultaneously maximize data throughput, minimize energy consumption, and maintain equitable resource distribution. The proposed RMAPPO framework incorporates recurrent neural networks (RNNs) to model temporal dependencies in UAV mobility patterns and utilizes a decentralized multi-agent More >

  • Open Access

    ARTICLE

    Real-World Data on Stage III Non-Small Cell Lung Cancer in Vietnam

    Khanh Toan Nguyen1,*, Thi Huong Pham1,2, Van Lam Ngo1, Thi Thuy My Nguyen1, Thi Dao Nguyen1, Khanh Hung Truong1, Van Nhat Nguyen1, Van Thanh Le1, Ba Duc Ho1, Thi Phuong Thao Nguyen1, Thi Ha Phuong Nguyen1, Thi My Linh Dinh1, Thi Hong Anh Vo1, Thi Thuy Phan1, Thi Hai Yen Le1, Thi Nhung Ngo1, Khanh Ha Nguyen1

    Oncology Research, Vol.33, No.12, pp. 4013-4028, 2025, DOI:10.32604/or.2025.069281 - 27 November 2025

    Abstract Objective: Patients with stage III non-small cell lung cancer (NSCLC) present with a heterogeneous disease profile and often require multifaceted treatment strategies. This research aimed to investigate the demographic features, therapeutic patterns, and survival outcomes of such patients in Vietnam. Methods: A retrospective descriptive study was conducted on 731 patients diagnosed with stage III NSCLC American Joint Committee on Cancer (AJCC) 8th edition, at Nghe An Oncology Hospital from January 2018 to August 2024. Descriptive statistics summarized baseline and treatment characteristics. We calculated progression-free survival (PFS) and overall survival (OS) through the Kaplan–Meier approach and… More >

  • Open Access

    ARTICLE

    Efficient Malicious QR Code Detection System Using an Advanced Deep Learning Approach

    Abdulaziz A. Alsulami1, Qasem Abu Al-Haija2,*, Badraddin Alturki3, Ayman Yafoz1, Ali Alqahtani4, Raed Alsini1, Sami Saeed Binyamin5

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 1117-1140, 2025, DOI:10.32604/cmes.2025.070745 - 30 October 2025

    Abstract QR codes are widely used in applications such as information sharing, advertising, and digital payments. However, their growing adoption has made them attractive targets for malicious activities, including malware distribution and phishing attacks. Traditional detection approaches rely on URL analysis or image-based feature extraction, which may introduce significant computational overhead and limit real-time applicability, and their performance often depends on the quality of extracted features. Previous studies in malicious detection do not fully focus on QR code security when combining convolutional neural networks (CNNs) with recurrent neural networks (RNNs). This research proposes a deep learning… More >

  • Open Access

    ARTICLE

    Transfer Learning-Based Approach with an Ensemble Classifier for Detecting Keylogging Attack on the Internet of Things

    Yahya Alhaj Maz1, Mohammed Anbar1, Selvakumar Manickam1,*, Mosleh M. Abualhaj2, Sultan Ahmed Almalki3, Basim Ahmad Alabsi4

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5287-5307, 2025, DOI:10.32604/cmc.2025.068257 - 23 October 2025

    Abstract The Internet of Things (IoT) is an innovation that combines imagined space with the actual world on a single platform. Because of the recent rapid rise of IoT devices, there has been a lack of standards, leading to a massive increase in unprotected devices connecting to networks. Consequently, cyberattacks on IoT are becoming more common, particularly keylogging attacks, which are often caused by security vulnerabilities on IoT networks. This research focuses on the role of transfer learning and ensemble classifiers in enhancing the detection of keylogging attacks within small, imbalanced IoT datasets. The authors propose… More >

  • Open Access

    REVIEW

    Biomass-Derived Carbon-Based Nanomaterials: Current Research, Trends, and Challenges

    Robyn Lesch1, Evan David Visser1, Ntalane Sello Seroka1,2,*, Lindiwe Khotseng1,*

    Journal of Renewable Materials, Vol.13, No.10, pp. 1935-1977, 2025, DOI:10.32604/jrm.2025.02025-0026 - 22 October 2025

    Abstract The review investigates the use of biomass-derived carbon as precursors for nanomaterials, acknowledging their sustainability and eco-friendliness. It examines various types of biomasses, such as agricultural residues and food byproducts, focussing on their transformation via environmentally friendly methods such as pyrolysis and hydrothermal carbonisation. Innovations in creating porous carbon nanostructures and heteroatom surface functionalisation are identified, enhancing catalytic performance. The study also explores the integration of biomass-derived carbon with nanomaterials for energy storage, catalysis, and other applications, noting the economic and environmental benefits. Despite these advantages, challenges persist in optimising synthesis methods and scaling production. More > Graphic Abstract

    Biomass-Derived Carbon-Based Nanomaterials: Current Research, Trends, and Challenges

  • Open Access

    REVIEW

    Advances in Tissue-Agnostic Targeting in Cancer Therapeutics: Current Approvals, Challenges, and Future Directions

    Matthew Rubinstein1,*, Madeline Lauren Hong1, Rishi Kumar Nanda1, Daniel Thomas Jones1, Hazem Aboaid2, Yin Mon Myat3, Kyaw Zin Thein4

    Oncology Research, Vol.33, No.11, pp. 3161-3183, 2025, DOI:10.32604/or.2025.067791 - 22 October 2025

    Abstract The ever-expanding development of tissue-agnostic therapies which target malignancies based on specific mutations rather than tissue origin have transformed the landscape of oncology. The purpose of this review is to explore the impact, safety, and challenges of tissue-agnostic therapies including pembrolizumab, dostarlimab, larotrectinib, entrectinib, repotrectinib, dabrafenib plus trametinib, selpercatinib, and trastuzumab deruxtecan. As the therapeutic arsenal continues to grow, it is crucial to understand how these therapies truly benefit patients and to address the barriers that stand in the way of making them more widely available. Although these therapies have shown effectiveness across multiple cancer More >

  • Open Access

    REVIEW

    Immune Checkpoint Inhibitors in Gastrointestinal Cancers: Current Evidence and Future Directions

    Takeshi Toyozumi1,*, Hideaki Shimada2, Hisahiro Matsubara1

    Oncology Research, Vol.33, No.11, pp. 3185-3206, 2025, DOI:10.32604/or.2025.065818 - 22 October 2025

    Abstract Cancer immunotherapy has long been established as an important treatment option for cancers. In particular, Immune Checkpoint Inhibitor (ICI) has been reported to be effective against various gastrointestinal cancers (esophageal cancer, gastric cancer, colorectal cancer); however, the treatment phase in which ICI should be used and how it should be incorporated into the treatment strategy vary depending on the cancer type being treated. Multiple clinical trials and basic research on ICIs are currently underway, and new insights from these results will continue to change the clinical treatment strategy of gastrointestinal cancers. While it is desirable… More >

  • Open Access

    ARTICLE

    Parasitic Shunt Currents in Alkaline Water Electrolysis (AWE) for Generating Clean Hydrogen

    Tuhid Pashaee Golmarz1, Seyyed Kazem Yekani1,*, Ebrahim Abdi aghdam2

    Energy Engineering, Vol.122, No.10, pp. 4121-4134, 2025, DOI:10.32604/ee.2025.067446 - 30 September 2025

    Abstract Since the beginning of the 20th century, alkaline electrolysis has been used as a proven method for producing hydrogen on a megawatt scale. The existence of parasitic shunt currents in alkaline water electrolysis, which is utilized to produce clean hydrogen, is investigated in this work. Analysis has been done on a 20-cell stack. Steel end plates, bipolar plates, and an electrolyte concentration of 6 M potassium hydroxide are all included in the model. The Butler-Volmer kinetics equations are used to simulate the electrode surfaces. Ohmic losses are taken into consideration in both the electrode and… More >

  • Open Access

    ARTICLE

    Load Balancing Control Strategy for Multi-Substation Flexible Interconnection Distribution Networks Considering Unbalanced Power Compensation

    Qiji Dai1, Jikai Li2,*, Bohui Ning1, Yutao Xu1, Chang Liu2, Xuan Zhang1

    Energy Engineering, Vol.122, No.10, pp. 4061-4080, 2025, DOI:10.32604/ee.2025.067304 - 30 September 2025

    Abstract Aiming at the challenge of complex load balancing coordination for a three-phase four-leg (3P4L) based multi-ended low voltage flexible DC distribution system (M-LVDC) considering unbalanced power compensation, this paper proposes a phase-split power decoupling unbalanced compensation strategy based load balancing strategy for 3P4L based M-LVDC. Firstly, the topology and operation principle of the 3P4L-based M-LVDC system is introduced, and quasi-proportional resonant (QPR) based phase-split power current control for the 3P4L converter is proposed. Secondly, a load-balancing control strategy considering unbalanced compensation for 3P4L-based M-LVDC is presented, in which the control diagrams for each 3P4L-based converter… More >

  • Open Access

    ARTICLE

    Calculation of Commutation Failure Overvoltage in High-Voltage Direct Current Transmission Terminal Systems with Grid-Forming Renewable Energy Sources

    Weibing Xu1, Bo Yao2,*, Xiangjun Quan3, Xunyou Zhang1, Ning Zou2, Shuo Liu2, Jia Wang4, Jiansuo Zhang4

    Energy Engineering, Vol.122, No.10, pp. 4225-4243, 2025, DOI:10.32604/ee.2025.066738 - 30 September 2025

    Abstract The integration of large-scale new energy and high-capacity DC transmission leads to a reduction in system inertia. Grid-forming renewable energy sources (GF-RES) has a significant improvement effect on system inertia. Commutation failure faults may cause a short-term reactive power surplus at the sending end and trigger transient overvoltage, threatening the safe and stable operation of the power grid. However, there is a lack of research on the calculation method of transient overvoltage caused by commutation failure in high-voltage DC transmission systems with grid-forming renewable energy sources integration. Based on the existing equivalent model of high-voltage… More >

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