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  • Open Access

    ARTICLE

    Facile Synthesis of a Novel Bio-Based P-N Containing Flame Retardant for Effectively Reducing the Fire Hazards of Epoxy Resin

    Meixian Li1, Xin Hu1, Jie Yang1, Hongyu Yang1,3,*, Yao Yuan2,*

    Journal of Renewable Materials, Vol.10, No.10, pp. 2639-2654, 2022, DOI:10.32604/jrm.2022.019491

    Abstract In this work, a bio-based flame retardant (Cy-HEDP) was synthesized from cytosine and HEDP through a facile salt-forming reaction and embedded into epoxy matrix to improve the flame retardancy and smoke suppression performance. The product Cy-HEDP was well characterized by FTIR, 1 H and 31P NMR and SEM tests. On the basis of the results, by adding 15 wt% Cy-HEDP, the EP15 can pass UL-94 V-0 rating, and the total smoke production (TSP) as well as total heat release (THR) can be decreased by 61.05% (from 22.61 to 8.7 m2 /m2 ) and 39.44% (from 103.19 to 62.50 MJ/m2 )… More > Graphic Abstract

    Facile Synthesis of a Novel Bio-Based P-N Containing Flame Retardant for Effectively Reducing the Fire Hazards of Epoxy Resin

  • Open Access

    ARTICLE

    Tet methylcytosine dioxygenase 2 suppresses renal cell cancer proliferation and metastasis by regulating the miR-200c-SCD axis

    BENJIANG QIAN1, YOUFENG HUANG2, ZHENQIANG QIU2, XIAOYAN YING3, GUANG YANG3, HUIZHANG LI2,*, JIANMING TAN1,*

    BIOCELL, Vol.45, No.3, pp. 599-615, 2021, DOI:10.32604/biocell.2021.014633

    Abstract Tet methylcytosine dioxygenase 2 (TET2) acts as an antioncogene that is investigated in different cancers. But the effects of TET2 in renal cell cancer (RCC) is still known little. Here, quantitative real-time PCR (qRT-PCR), Western blot, and immunofluorescence were performed to exam gene and protein expression. Cell proliferation was measured using Cell Counting Kit-8 (CCK-8). Transwell assay was performed to detect cell metastasis viability. Flow cytometry was performed to analyze the cell cycle and cell apoptosis. The effects of TET2 on RCC growth in vivo was analyzed using a mouse xenograft model.We found that TET2 and miR-200c were decreased in… More >

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