Mohamed A. Meselhi^*, Saber M. Elsayed, Daryl L. Essam, Ruhul A. Sarker

CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 1-17, 2023, DOI:10.32604/cmc.2023.027448

Abstract Dynamic constrained optimization is a challenging research topic in which the objective function and/or constraints change over time. In such problems, it is commonly assumed that all problem instances are feasible. In reality some instances can be infeasible due to various practical issues, such as a sudden change in resource requirements or a big change in the availability of resources. Decision-makers have to determine whether a particular instance is feasible or not, as infeasible instances cannot be solved as there are no solutions to implement. In this case, locating the nearest feasible solution would be valuable information for the decision-makers.… More >

Faizan Rasheed¹, Kok-Lim Alvin Yau², Rafidah Md Noor³, Yung-Wey Chong^4,*

CMC-Computers, Materials & Continua, Vol.71, No.2, pp. 2225-2247, 2022, DOI:10.32604/cmc.2022.022952

Abstract This paper investigates the use of multi-agent deep Q-network (MADQN) to address the curse of dimensionality issue occurred in the traditional multi-agent reinforcement learning (MARL) approach. The proposed MADQN is applied to traffic light controllers at multiple intersections with busy traffic and traffic disruptions, particularly rainfall. MADQN is based on deep Q-network (DQN), which is an integration of the traditional reinforcement learning (RL) and the newly emerging deep learning (DL) approaches. MADQN enables traffic light controllers to learn, exchange knowledge with neighboring agents, and select optimal joint actions in a collaborative manner. A case study based on a real traffic… More >

Moustafa El-shahed^1,*, Asmaa M. Al-Dububan²

Computer Systems Science and Engineering, Vol.40, No.2, pp. 749-764, 2022, DOI:10.32604/csse.2022.019655

Abstract In this paper, a deterministic and stochastic fractional order model for lesser date moth (LDM) using mating disruption and natural enemies is proposed and analysed. The interaction between LDM larvae, fertilized LDM female, unfertilized LDM female, LDM male and the natural enemy is investigated. In order to clarify the characteristics of the proposed deterministic fractional order model, the analysis of existence, uniqueness, non-negativity and boundedness of the solutions of the proposed fractional-order model are examined. In addition, some sufficient conditions are obtained to ensure the local and global stability of equilibrium points. The occurrence of local bifurcation near the equilibrium… More >

HATİCE BÜŞRA KONUK, BENGÜ ERGÜDEN^*

BIOCELL, Vol.41, No.1, pp. 13-18, 2017, DOI:10.32604/biocell.2017.41.013

Abstract Antifungal activity and mode of action of nine essential oils (EOs) against S. cerevisiae cells were examined. Antifungal effects of commercial lemon peel, orange peel, tea tree, turpentine, rosemary, peppermint, thyme, oregano and clove oils were determined through Minimum Inhibitory Concentration (MIC), Minimum Fungicidal Concentration (MFC) and inhibition zone measurements. The most effective oil was turpentine oil. Orange peel, thyme and oregano oils were also effective, according to MIC and MFC. Inhibition zone measurements, also revealed oregano, orange peel, thyme, turpentine and clove oils as most efficient ones. Later, membrane damage of yeast cells was studied by measuring the extracellular… More >

Nan Shen^1,2, Dabajyoti Datta¹, Chris B. Schaffer^1,3,4,5, Eric Mazur^1,6

Molecular & Cellular Biomechanics, Vol.2, No.1, pp. 17-26, 2005, DOI:10.3970/mcb.2005.002.017

Abstract Analysis of cell regulation requires methods for perturbing molecular processes within living cells with spatial discrimination on the nanometer-scale. We present a technique for ablating molecular structures in living cells using low-repetition rate, low-energy femtosecond laser pulses. By tightly focusing these pulses beneath the cell membrane, we ablate cellular material inside the cell through nonlinear processes. We selectively removed sub-micrometer regions of the cytoskeleton and individual mitochondria without altering neighboring structures or compromising cell viability. This nanoscissor technique enables non-invasive manipulation of the structural machinery of living cells with several-hundred-nanometer resolution. Using this approach, we unequivocally demonstrate that mitochondria are… More >