Siti Ramadhani1,2, Lestari Handayani2, Theam Foo Ng3, Sumayyah Dzulkifly1, Roziana Ariffin4,5, Haldi Budiman6, Shir Li Wang1,7,*
CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.3, pp. 2711-2765, 2025, DOI:10.32604/cmes.2025.062709
- 30 June 2025
Abstract In recent years, feature selection (FS) optimization of high-dimensional gene expression data has become one of the most promising approaches for cancer prediction and classification. This work reviews FS and classification methods that utilize evolutionary algorithms (EAs) for gene expression profiles in cancer or medical applications based on research motivations, challenges, and recommendations. Relevant studies were retrieved from four major academic databases–IEEE, Scopus, Springer, and ScienceDirect–using the keywords ‘cancer classification’, ‘optimization’, ‘FS’, and ‘gene expression profile’. A total of 67 papers were finally selected with key advancements identified as follows: (1) The majority of papers… More >
Graphic Abstract