Abdul Qadir Khan¹, Guangmin Sun^1,*, Yu Li¹, Anas Bilal², Malik Abdul Manan¹

CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 2481-2504, 2023, DOI:10.32604/cmc.2023.043239

Abstract In the emerging field of image segmentation, Fully Convolutional Networks (FCNs) have recently become prominent. However, their effectiveness is intimately linked with the correct selection and fine-tuning of hyperparameters, which can often be a cumbersome manual task. The main aim of this study is to propose a more efficient, less labour-intensive approach to hyperparameter optimization in FCNs for segmenting fundus images. To this end, our research introduces a hyperparameter-optimized Fully Convolutional Encoder-Decoder Network (FCEDN). The optimization is handled by a novel Genetic Grey Wolf Optimization (G-GWO) algorithm. This algorithm employs the Genetic Algorithm (GA) to generate a diverse set of… More >

Sayyid Kamran Hussain¹, Ali Haider Khan^2,*, Malek Alrashidi³, Sajid Iqbal⁴, Qazi Mudassar Ilyas⁴, Kamran Shah⁵

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3763-3781, 2023, DOI:10.32604/cmc.2023.041722

Abstract As ocular computer-aided diagnostic (CAD) tools become more widely accessible, many researchers are developing deep learning (DL) methods to aid in ocular disease (OHD) diagnosis. Common eye diseases like cataracts (CATR), glaucoma (GLU), and age-related macular degeneration (AMD) are the focus of this study, which uses DL to examine their identification. Data imbalance and outliers are widespread in fundus images, which can make it difficult to apply many DL algorithms to accomplish this analytical assignment. The creation of effcient and reliable DL algorithms is seen to be the key to further enhancing detection performance. Using the analysis of images of… More >

Ali Haider Khan^1,2,*, Hassaan Malik², Wajeeha Khalil³, Sayyid Kamran Hussain⁴, Tayyaba Anees⁵, Muzammil Hussain²

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 133-150, 2023, DOI:10.32604/cmc.2023.039518

Abstract To prevent irreversible damage to one’s eyesight, ocular diseases (ODs) need to be recognized and treated immediately. Color fundus imaging (CFI) is a screening technology that is both effective and economical. According to CFIs, the early stages of the disease are characterized by a paucity of observable symptoms, which necessitates the prompt creation of automated and robust diagnostic algorithms. The traditional research focuses on image-level diagnostics that attend to the left and right eyes in isolation without making use of pertinent correlation data between the two sets of eyes. In addition, they usually only target one or a few different… More >

N. M. Balamurugan^1,*, K. Maithili², T. K. S. Rathish Babu³, M. Adimoolam⁴

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 499-514, 2023, DOI:10.32604/iasc.2023.031661

Abstract Diabetic Eye Disease (DED) is a fundamental cause of blindness in human beings in the medical world. Different techniques are proposed to forecast and examine the stages in Prognostication of Diabetic Retinopathy (DR). The Machine Learning (ML) and the Deep Learning (DL) algorithms are the predominant techniques to project and explore the images of DR. Even though some solutions were adapted to challenge the cause of DR disease, still there should be an efficient and accurate DR prediction to be adapted to refine its performance. In this work, a hybrid technique was proposed for classification and prediction of DR. The… More >

CARL RANDALL HARRELL^1,#, ANA VOLAREVIC^2,#,*, DRAGICA PAVLOVIC³, VALENTIN DJONOV⁴, VLADISLAV VOLAREVIC^4,5,*

BIOCELL, Vol.46, No.10, pp. 2195-2200, 2022, DOI:10.32604/biocell.2022.020175

Abstract Detrimental immune response has a crucially important role in the development and progression of inflammatory eye diseases. Inflammatory mediators and proteolytic enzymes released by activated immune cells induce serious injury of corneal epithelial cells and retinal ganglion cell which may result in the vision loss. Mesenchymal stem cells (MSCs) are regulatory cells which produce various immunosuppressive factors that modulate phenotype and function of inflammatory immune cells. However, several safety issues, including undesired differentiation and emboli formation, limit clinical use of MSCs. MSC-derived exosomes (MSC-Exos) are nano-sized extracellular vesicles which contain all MSC-derived immunoregulatory factors. Intraocular administration of MSC-Exos efficiently attenuated… More >

Ghulam Ali Mallah¹, Jamil Ahmed¹, Muhammad Irshad Nazeer^2,*, Mazhar Ali Dootio³, Hidayatullah Shaikh¹, Aadil Jameel¹

CMC-Computers, Materials & Continua, Vol.71, No.3, pp. 5343-5353, 2022, DOI:10.32604/cmc.2022.023581

Abstract Detection of abnormalities in human eye is one of the well-established research areas of Machine Learning. Deep Learning techniques are widely used for the diagnosis of Retinal Diseases (RD). Fovea is one of the significant parts of retina which would be prevented before the involvement of Perforated Blood Vessels (PBV). Retinopathy Images (RI) contains sufficient information to classify structural changes incurred upon PBV but Macular Features (MF) and Fovea Features (FF) are very difficult to detect because features of MF and FF could be found with Similar Color Movements (SCM) with minor variations. This paper presents novel method for the… More >

Ye Mu^1,2,3,4, Yuheng Sun¹, Tianli Hu^1,2,3,4, He Gong^1,2,3,4, Shijun Li^1,2,3,4,*, Thobela Louis Tyasi⁵

Intelligent Automation & Soft Computing, Vol.28, No.3, pp. 729-737, 2021, DOI:10.32604/iasc.2021.016569

Abstract The rapid development of computer vision technology and digital images has increased the potential for using image recognition for eye disease diagnosis. Many early screening and diagnosis methods for ocular diseases based on retinal images of the fundus have been proposed recently, but their accuracy is low. Therefore, it is important to develop and evaluate an improved VGG model for the recognition and classification of retinal fundus images. In response to these challenges, to solve the problem of accuracy and reliability of clinical algorithms in medical imaging this paper proposes an improved model for early recognition of ophthalmopathy in retinal… More >

Nakhim Chea¹, Yunyoung Nam^2,*

CMC-Computers, Materials & Continua, Vol.67, No.1, pp. 411-426, 2021, DOI:10.32604/cmc.2021.013390

Abstract Various techniques to diagnose eye diseases such as diabetic retinopathy (DR), glaucoma (GLC), and age-related macular degeneration (AMD), are possible through deep learning algorithms. A few recent studies have examined a couple of major diseases and compared them with data from healthy subjects. However, multiple major eye diseases, such as DR, GLC, and AMD, could not be detected simultaneously by computer-aided systems to date. There were just high-performance-outcome researches on a pair of healthy and eye-diseased group, besides of four categories of fundus image classification. To have a better knowledge of multi-categorical classification of fundus photographs, we used optimal residual… More >