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  • Open Access

    ARTICLE

    A Study on the Fatigue Failure Characteristics of Steel Bridge Deck Pavement Layers under Dynamic Loads

    Jiyi Li1, Zongqi Xiong2, Xinxin Cao3,*

    Structural Durability & Health Monitoring, Vol.20, No.5, 2026, DOI:10.32604/sdhm.2026.083367 - 24 August 2026

    Abstract In response to the common interlaminar shear and delamination defects in the pavement of long-span steel bridges, this paper investigates the interface fatigue failure mechanism of the “SMA-13 + epoxy resin + orthotropic steel plate” system. Static direct shear tests indicate that the optimal application rate of epoxy resin is 1.5 kg/m2, and that elevated temperatures cause the failure mode to transition from brittle fracture to ductile creep. Based on full-factorial dynamic shear fatigue tests, this study discarded subjective empirical thresholds and innovatively proposed the “geometric tangent method” to quantitatively define fatigue life. Analysis of variance More >

  • Open Access

    ARTICLE

    Experimental Study on the Tensile Performance of Fully Grouted Sleeve Connections after High-Temperature Exposure

    Ning Lin*

    Structural Durability & Health Monitoring, Vol.20, No.5, 2026, DOI:10.32604/sdhm.2026.080823 - 24 August 2026

    Abstract The fully grouted sleeve connection is a key joint type in precast concrete structures. Its mechanical performance after high-temperature exposure is critical for the post-fire safety assessment of these structures. This paper experimentally investigates the influence of different peak temperatures on the tensile performance of fully grouted sleeve connections. A total of 36 fully grouted sleeve specimens, 36 single rebar specimens, and their corresponding grout cubes were prepared. All specimens were heated to the target temperatures and then cooled naturally. Afterwards, static tensile tests and compressive strength tests were performed. The results show that, compared… More >

  • Open Access

    ARTICLE

    Pathologic failure and salvage approaches following focal therapy for localized prostate cancer

    Samuel Tremblay1,#,*, Seyed Sajjad Tabei2,#, Shima Tayebi3, Benjamin H. Hinrichs4, Alon Lazarovich1, Jason Koehler3, Wei-Wen Hsu5, Sadhna Verma3, Abhinav Sidana1

    Canadian Journal of Urology, Vol.33, No.4, pp. 799-810, 2026, DOI:10.32604/cju.2026.075779 - 21 August 2026

    Abstract Background: Focal therapy (FT) is an emerging treatment modality for localized prostate cancer. However, limited data are available regarding the patterns of oncologic failure post-FT. This study aims to characterize the features of oncologic failure and salvage strategies following FT. Methods: Patients presenting with pathologic failure (PF) after receiving FT (cryotherapy, High-intensity focused ultrasound, or irreversible electroporation) for intermediate-risk prostate cancer were selected from a prospective registry between 2018 and 2023. All patients underwent protocol-based follow-up, including PSA testing, multiparametric MRI, and mandatory biopsy. The primary outcome was PF, defined as biopsy-confirmed Grade Group ≥2… More >

  • Open Access

    REVIEW

    The Advanced Cardiac Therapies Improving Outcomes Network (ACTION): A Multicenter Registry and Learning Health System for Pediatric and Congenital Heart Disease Associated Heart Failure

    Anusha Konduri1,*, Toni Duganiero2, Lauren Smyth2, Shahnawaz Amdani3, Angela Lorts2, Sabrina Law4, Jacqueline Lamour5, Deipanjan Nandi6, Aryaz Sheybani7, Sarah Wilkens8, Thomas Young9, Mark Bleiweis10, Jennifer Conway11

    Structural and Congenital Heart Disease, Vol.21, No.3, 2026, DOI:10.32604/schd.2026.082288 - 31 July 2026

    Abstract Pediatric heart failure is associated with substantial morbidity, mortality, and health care utilization across diverse diagnoses and care settings. Despite major advances in surgical and medical care, evidence-based management of heart failure in the pediatric population, especially with congenital heart disease (CHD), remains limited due to a small patient population, marked anatomic and physiologic heterogeneity, and barriers to conducting traditional randomized clinical trials. Clinical registries have provided important insights into pediatric heart failure, and the increasing complexity of these populations has underscored the value of learning health system approaches to data generation and improvement. The… More >

  • Open Access

    ARTICLE

    A Unified Physics-of-Failure Framework for Reliability Prediction of SiC MOSFET Inverters under Stochastic Mission Profiles

    Mohammed Ansar Mohammed Manaz1,*, Shang Ping Hong2, Tzung-Lin Lee1

    CMES-Computer Modeling in Engineering & Sciences, Vol.148, No.1, 2026, DOI:10.32604/cmes.2026.083270 - 27 July 2026

    Abstract Silicon Carbide Metal Oxide Semiconductor Field Effect Transistors (SiC MOSFETs) have superior characteristics compared to traditional Silicon-based switching devices. SiC devices can support fast switching speeds and high blocking voltages. Due to limited historical data and rapid technological improvements, there is not enough field data to correctly evaluate the reliability of the state-of-the-art SiC MOSFETs. An accurate model of their reliability and aging characteristics is needed to expedite their rapid commercial adoption in mission-critical applications, such as offshore wind farms and electric vehicles. Classical handbook-based methods produce large errors due to their inability to correctly… More >

  • Open Access

    ARTICLE

    Instantaneous Mobility Indicators for Risk Management in Wind Farms: A Computer Modeling Approach

    Guglielmo D’Amico1,*, Edoardo Lui2, Filippo Petroni1

    CMES-Computer Modeling in Engineering & Sciences, Vol.148, No.1, 2026, DOI:10.32604/cmes.2026.082608 - 27 July 2026

    Abstract This paper develops an operational framework for short-horizon risk management in multistate stochastic systems, with application to wind farm performance. We focus on instantaneous mobility-based indicators derived from finite-state continuous-time Markov chains, which capture the local propensity of a system to transition between states. Unlike classical reliability and availability measures, these indicators provide a dynamic description of system behavior. The indicators are interpreted as policy signals to support decision-making under budget constraints. We introduce a state-conditional expected short-horizon loss, representing non-production risk, and use it to evaluate ranking-based intervention strategies. The framework is applied to More >

  • Open Access

    ARTICLE

    Bond Behavior of NPR Bar/Steel Strands with Ultra-High-Performance Concrete

    Qinfeng Pan1, Wei Zhang1, Hao Chen1, Lin Pang2, Xiang Liu1,*, Chun Chieh Yip3

    Structural Durability & Health Monitoring, Vol.20, No.4, 2026, DOI:10.32604/sdhm.2026.083328 - 30 June 2026

    Abstract Ultra-high-performance concrete (UHPC) exhibits high strength, toughness, and durability, making it an excellent candidate for integration with novel high-ductility, high-strength negative Poisson’s ratio (NPR) steel bars. This combination shows promising applications in the fields of bridges and buildings. This study investigates the bonding performance of various types of NPR bars (smooth NPR bars, spiral rib NPR bars, and NPR steel strands) with UHPC as the concrete matrix. It examines the effects of bond length, bar diameter, and NPR bar type on bonding performance, comparing these results with those of normal concrete (NC). A predictive model… More >

  • Open Access

    REVIEW

    Cellular Senescence in the Cardiovascular System: Molecular Mechanisms, Pathophysiology, and Senotherapeutic Interventions

    Beata Franczyk1, Anna Bajer1,#, Anna Bulicz1,#, Mikołaj Grabarczyk1,#, Paulina Jakubowska1,#, Katarzyna Krawiranda1,#, Natalia Kustosik1,#, Przemysław Kuzar1,#, Klaudia Leszto1,#, Maja Mejza1,#, Weronika Mstowska1,#, Jacek Rysz2, Ewelina Młynarska1,*

    BIOCELL, Vol.50, No.7, 2026, DOI:10.32604/biocell.2026.075767 - 29 June 2026

    Abstract Cellular senescence and the Senescence-Associated Secretory Phenotype (SASP) play both physiological and pathological roles in the cardiovascular system. While transient senescence aids regeneration, chronic accumulation of senescent cells promotes endothelial dysfunction, arterial stiffening, and maladaptive cardiac remodeling. This review elucidates the pivotal role of the immune system in senescent cell clearance and explores how immunosenescence drives systemic low-grade inflammation. Significant emphasis is placed on emerging pharmacological strategies, specifically senolytics and senomorphics, assessing their capacity to restore cardiac function and attenuate atherosclerosis. Additionally, the utility of molecular biomarkers and diverse in vitro and in vivo models is analyzed More >

  • Open Access

    ARTICLE

    Cascading Failure Dynamics and Edge-Intelligent Defense in Space-Air-Ground Integrated Networks for Internet of Things

    Peiying Zhang1,2, Yihong Yu1,2, Lizhuang Tan3,4,*, Shuqing He5, Jian Wang6, Ameer El-Sayed7

    CMC-Computers, Materials & Continua, Vol.88, No.2, 2026, DOI:10.32604/cmc.2026.081224 - 15 June 2026

    Abstract As a core information infrastructure in the 6G era, the Space-Air-Ground Integrated Network (SAGIN) integrates space-based, air-based, and ground-based network resources to achieve seamless communication across all domains. However, its characteristics such as heterogeneous node coupling and dynamic topology changes make it prone to cascading failures, severely threatening critical business continuity in Internet of Things (IoT) applications spanning smart cities, healthcare, transportation, and industrial automation. This paper conducts systematic research addressing challenges including modeling difficulties in SAGIN cascading failure propagation, insufficient coordination of defense strategies, and poor resource adaptability. First, a multi-factor coupled dynamic model… More >

  • Open Access

    ARTICLE

    Satellite Failure Prognosis with Cascaded Temporal Convolution and Transformer Network for Multi-Scale Features

    Yu Shi1, Yunfeng Dong1,*, Lu Tian2,3

    CMC-Computers, Materials & Continua, Vol.88, No.2, 2026, DOI:10.32604/cmc.2026.080577 - 15 June 2026

    Abstract Failure prognosis provides critical decision-making support for Integrated System Health Management (ISHM), ensuring the operational safety of satellites in orbit. Temporal Convolutional Networks (TCNs), known for their capability in processing time-series data, have become an important approach for failure prognosis. The gradual performance degradation of satellites, combined with multi-physics coupling effects, gives rise to multi-scale features. However, existing TCN based failure prognosis methods remain limited in their ability to simultaneously capture both local and global features, posing challenges when processing such multi-scale features. To address this issue, a Cascaded Temporal Convolution and Transformer Network (CTCTN)… More >

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