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  • Open Access

    ARTICLE

    Dynamic Spatial Focus in Alzheimer’s Disease Diagnosis via Multiple CNN Architectures and Dynamic GradNet

    Jasem Almotiri*

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2109-2142, 2025, DOI:10.32604/cmc.2025.062923 - 16 April 2025

    Abstract The evolving field of Alzheimer’s disease (AD) diagnosis has greatly benefited from deep learning models for analyzing brain magnetic resonance (MR) images. This study introduces Dynamic GradNet, a novel deep learning model designed to increase diagnostic accuracy and interpretability for multiclass AD classification. Initially, four state-of-the-art convolutional neural network (CNN) architectures, the self-regulated network (RegNet), residual network (ResNet), densely connected convolutional network (DenseNet), and efficient network (EfficientNet), were comprehensively compared via a unified preprocessing pipeline to ensure a fair evaluation. Among these models, EfficientNet consistently demonstrated superior performance in terms of accuracy, precision, recall, and… More >

  • Open Access

    ARTICLE

    Genomic Characterization of BvMLO Genes in Sugar Beet Focusing on BvMLO2 BvMLO7 Responses to Cercospora beticola and Abiotic Stress

    Ran Li1,#, Liuhong Chen1,#, Yu Liu1, Chunlei Zhao1,2, Yanli Li1,2, Guangzhou Ding1,2,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 875-895, 2025, DOI:10.32604/phyton.2025.061550 - 31 March 2025

    Abstract Mildew resistance locus O (MLO) proteins are extensively found in various plant species and are essential for multiple biological functions. The characterization and analysis of MLO genes have been conducted across numerous species. However, the functions and features of MLO genes inside sugar beet remain poorly understood. In the present research, we conducted a comprehensive analysis of the structural features of MLO genes, physicochemical characteristics of proteins, evolutionary connections, and expression profiles in sugar beet. A total of 13 BvMLO genes containing MLO structural domains were detected and renamed based on their locations on chromosomes within the sugar… More >

  • Open Access

    COMMENTARY

    Retinal Focus on Relationships between Diet-Induced, Advanced Glycation End Products and Supplemental Estradiol

    Nicholas T. Bello1, Bonnie L. Firestein2, Maribel Vazquez3,*

    BIOCELL, Vol.49, No.3, pp. 349-354, 2025, DOI:10.32604/biocell.2025.061810 - 31 March 2025

    Abstract Neurodegeneration of retinal tissue leads to progressive vision loss in millions of working-age adults each year. Metabolic alterations caused by modern diets that are high in fats and sugars contribute to the development of diabetic retinopathy. Chronic, diet-induced metabolic changes are linked to high glucose and harmful, pro-inflammatory compounds in the blood, called advanced glycation end products (AGEs), that can alter the integrity of neurovascular barriers. AGEs-induced changes to the permeability of the inner blood-retinal barrier can lead to progressive vision loss with disparate impacts in patients with low estrogen, such as via natural aging More >

  • Open Access

    ARTICLE

    The Influence of Gratitude on Coping Strategies: Indirect Effect Testing from Longitudinal Data

    Jun Zhang1,2,#,*, Junqiao Guo3,#

    International Journal of Mental Health Promotion, Vol.27, No.2, pp. 193-214, 2025, DOI:10.32604/ijmhp.2025.058022 - 03 March 2025

    Abstract Background: The academic community is increasingly interested in understanding the mechanisms through which gratitude influences coping strategies. In addition, the role of gratitude in fostering long-term resilience and mental health outcomes has garnered significant attention. This study explores the mechanisms through which gratitude affects problem-focused coping strategies and emotion-focused coping strategies by constructing models involving gratitude, perceived social support, self-esteem, and problem-focused coping strategies, as well as models involving gratitude, perceived social support, self-esteem, and emotion-focused coping strategies. Methods: A longitudinal survey was conducted on 1666 Chinese university students using highly reliable and valid scales,… More >

  • Open Access

    REVIEW

    Biochar, Properties and Skills with a Focus on Implications for Vineyard Land and Grapevine Performance

    Pamela Lippi, Giovan Battista Mattii, Eleonora Cataldo*

    Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 33-64, 2025, DOI:10.32604/phyton.2025.059997 - 24 January 2025

    Abstract Biochar has emerged as a promising tool for enhancing vineyard sustainability by improving soil properties and mitigating climate change impacts. This review highlights key findings on biochar’s role in viticulture, focusing on its effects on soil fertility, water retention, and plant physiology. Field and pot studies demonstrate that biochar amendments enhance soil structure, increase cation exchange capacity (CEC), and promote water availability, leading to improved drought resistance in grapevines. However, the impacts on grape yield, physiology, and quality remain inconclusive, with some studies reporting benefits while others show neutral effects. Future research should focus on More >

  • Open Access

    ARTICLE

    A costing and health-related quality of life study of high intensity focused ultrasound in primary treatment of localized low or intermediate risk prostate cancer in Ontario

    Bassem Toeama1, Nathan Perlis2, Paul Grootendorst1, William Orovan3, Emmanuel Papadimitropoulos1,4

    Canadian Journal of Urology, Vol.31, No.4, pp. 11963-11970, 2024

    Abstract Introduction: Prostate cancer is the third leading cause of death from cancer among Canadian men. High intensity focused ultrasound (HIFU) is a novel approach for primary treatment of localized prostate cancer. Little is known, however, about its costs. We aimed to collect the direct costs and health-related quality of life (HRQoL) data of HIFU in primary treatment of localized low and intermediate risk prostate cancer in Ontario.
    Materials and methods: We collected direct costs and HRQoL data of 20 patients with localized low or intermediate risk prostate cancer who received whole gland HIFU at a privately owned… More >

  • Open Access

    ARTICLE

    The Oxyalkylation of Hydrophilic Black Alder Bark Extractives with Propylene Carbonate with a Focus on Green Polyols Synthesis

    Alexandr Arshanitsa*, Matiss Pals, Daniela Godina, Oskars Bikovens

    Journal of Renewable Materials, Vol.12, No.11, pp. 1927-1948, 2024, DOI:10.32604/jrm.2024.056466 - 22 November 2024

    Abstract The isolated hydrophilic black alder (Alnus glutinosa) bark extractives were characterized in terms of component and functional composition and converted at 150°C–170°C into liquid green polyols using solvent-free and low-toxic base-catalyzed modification with propylene carbonate (PC). FTIR spectroscopy, HP-LC, GC, GPC, and wet chemistry methods were used to characterize the starting constituents, intermediate and final products of the reaction and to monitor the different pathways of PC conversion. The reaction of extractives as well as the model compounds, including catechol, xylose, PEG 400, and benzoic acid, with PC indicated the ability of OH groups of different… More > Graphic Abstract

    The Oxyalkylation of Hydrophilic Black Alder Bark Extractives with Propylene Carbonate with a Focus on Green Polyols Synthesis

  • Open Access

    REVIEW

    First Principles Calculations for Corrosion in Mg-Li-Al Alloys with Focus on Corrosion Resistance: A Comprehensive Review

    Muhammad Abdullah Khan1, Muhammad Usman2, Yuhong Zhao1,3,4,*

    CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 1905-1952, 2024, DOI:10.32604/cmc.2024.054691 - 18 November 2024

    Abstract This comprehensive review examines the structural, mechanical, electronic, and thermodynamic properties of Mg-Li-Al alloys, focusing on their corrosion resistance and mechanical performance enhancement. Utilizing first-principles calculations based on Density Functional Theory (DFT) and the quasi-harmonic approximation (QHA), the combined properties of the Mg-Li-Al phase are explored, revealing superior incompressibility, shear resistance, and stiffness compared to individual elements. The review highlights the brittleness of the alloy, supported by B/G ratios, Cauchy pressures, and Poisson’s ratios. Electronic structure analysis shows metallic behavior with varied covalent bonding characteristics, while Mulliken population analysis emphasizes significant electron transfer within the… More >

  • Open Access

    PROCEEDINGS

    Effect of Slender Bar Structures on the Boundary on Cavitation Bubble Dynamics Due to Self-Focusing Shockwaves

    Jiajun Cui1, Fabian Reuter2, Zhigang Zuo1,*, Shuhong Liu1,*, Claus-Dieter Ohl2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012155

    Abstract When cavitation bubbles collapse near a boundary, they can cause severe cavitation erosion to the boundary, which is a dangerous threat to the rapidly rotating turbines. Prior research has established that for single bubbles a possible mechanism is energy focusing of shockwaves during the non-spherical collapse of cavitation bubbles [1]. This however needs a particularly symmetric environment. A possible approach to reduce the shockwave focusing and thus the erosion would be through suitable modification of the boundary. In a first approach to modify this phenomenon, we introduce the symmetry breaking structure on the boundary in the shape of a slender bar to explore the effect More >

  • Open Access

    PROCEEDINGS

    On the Shock-Wave Self-Focusing Dynamics of a Single Collapsing Bubble: A Numerical Study

    Wentao Wu1, Qingyun Zeng1,2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-2, 2024, DOI:10.32604/icces.2024.012089

    Abstract The collapses of bubbles near rigid walls are seen widely in engineering and medical applications, examples are surface cleaning, sonoporation, under water explosion, and cavitation erosions, to name a few. Recent experimental studies demonstrated that only bubbles with extremely small stand-off distance γ (γ = d/Rmax, γ is stand-off distance, d is the initial distance of the bubble center to the boundary, and Rmax is the maximum radius the bubble would attain) generate severe erosions during the first oscillating circle. This erosion phenomenon, attributed to a self-focusing mechanism, lacks a comprehensive explanation. Here we provided… More >

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