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  • Open Access

    ARTICLE

    GC-MS Analysis, Antimicrobial Activity, and Genotoxicity of Pimpinella anisum Essential oil: In Vitro, ADMET and Molecular Docking Investigations

    Ahmed Qasem*

    Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 809-824, 2025, DOI:10.32604/phyton.2025.062683 - 31 March 2025

    Abstract Pimpinella anisum, commonly known as anise, is generally used in both folk medicine and the culinary world. In traditional medicine, it is valued for its digestive, respiratory, and antispasmodic properties. This study aims to examine the volatile compounds and antibacterial effect of P. anisum essential oil (PAEO) as well as for the first time its genotoxicity employing both in vitro and computational approaches. Gas chromatography-mass spectrometry (GC-MS) analysis identified anethole as the principal compound, which comprises 92.47% of PAEO. PAEO was tested for its potential antibacterial properties against Bacillus subtilis ATCC 6633, Listeria innocua ATCC 33090, Staphylococcus aureus ATCC 29213, Klebsiella aerogenesMore >

  • Open Access

    ARTICLE

    Comprehensive Assessment of the Safety of Eucommia ulmoides Leaf Extract for Consumption as a Traditional Chinese Health Food

    Huiling Fu1, Mijun Peng2, Qiuwen Tang2, Haojun Liang2, Yanli Liang2, Jiali Fang2,*, Xuesong Wang2,*

    Journal of Renewable Materials, Vol.11, No.7, pp. 3091-3114, 2023, DOI:10.32604/jrm.2023.026689 - 05 June 2023

    Abstract To ensure the export quality of Eucommia ulmoides leaf extract (ELE) and facilitate E. ulmoides leaf inclusion in the directory of traditional Chinese health foods, an overall safety assessment of ELE was performed, including genotoxicity and long-term toxicity, according to the national food safety standards of China. No variations in the reverse mutation number of the nominal bacterial strains were observed under ELE treatment in comparison with the solvent control. Additionally, the micronucleus rates of in vivo mammalian erythrocytes and in vitro mammalian cells under ELE treatment were equivalent to or significantly lower than those of the… More > Graphic Abstract

    Comprehensive Assessment of the Safety of <i>Eucommia ulmoides</i> Leaf Extract for Consumption as a Traditional Chinese Health Food

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