YOUNG HWA LEE¹, HEE SAM NA¹ , SO YEON JEONG¹, SUNG HEE JEONG² , HAE RYOUN PARK³ , JIN CHUNG^1*

BIOCELL, Vol.35, No.2, pp. 43-50, 2011, DOI:10.32604/biocell.2011.35.043

Abstract MicroRNAs (miRNAs) are short RNA molecules that negatively regulate gene expression primarily by degrading target mRNA or inhibit the translation of protein product. Recently, many reports have shown the altered miRNA expression in various diseases. However, there are no reports on miRNA expression related to periodontitis. Thus, this study aimed to compare the miRNAs differentially expressed in healthy and chronic periodontitis tissues and to determine the miRNAs closely associated with chronic periodontitis. To find out the miRNAs differentially induced in healthy and chronic periodontitis tissues, miRNA microarray was carried out and the expression of miRNAs was confirmed by real-time PCR.… More >

Moharam Habibnejad Korayem^1,*, Zahra Rastegar²

Molecular & Cellular Biomechanics, Vol.16, No.2, pp. 109-122, 2019, DOI:10.32604/mcb.2019.04706

Abstract The mechanical properties of single cells have been recently identified as the basis of an emerging approach in medical applications since they are closely related to the biological processes of cells and human health conditions. The problem in hand is how to measure mechanical properties in order to obtain them more accurately and applicably. Some of the cell’s properties such as elasticity module and adhesion have been measured before using various methods; nevertheless, comprehensive tests for two healthy and cancerous cells have not been performed simultaneously. As a Nanoscale device, AFM has been used for some biological cells, however for… More >

Dalin Tang^1,*,2, Heng Zuo^2,*, Chun Yang², Zheyang Wu², Xueying Huang³, Rahul H. Rathod⁴, Alexander Tang⁴, Kristen L. Billiar⁵, Tal Geva⁴

Molecular & Cellular Biomechanics, Vol.14, No.3, pp. 137-151, 2017, DOI:10.3970/mcb.2017.014.137

Abstract Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle failure. Comparing TOF patients with healthy people may provide information to address this challenge. Cardiac magnetic resonance (CMR) data were obtained from 16 TOF patients (patient group, PG) and 6 healthy volunteers (healthy group, HG). At begin-of-ejection, better patient group (n=5, BPG) stress was very close to HG stress (54.7±38.4 kPa vs. 51.2±55.7 kPa, p=0.6889) while worse patient group (n=11, WPG) stress was 84% higher than HG stress (p=0.0418). Stress may be used as an indicator to differentiate BPG patients from WPG… More >