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  • Open Access

    ABSTRACT

    Quantifying Heterogeneity of Cell-ECM Interactions Through Integrated Biophysical Analyses

    William Leineweber1, Stephanie I. Fraley1,2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 9-9, 2019, DOI:10.32604/mcb.2019.08504

    Abstract Cell-extracellular matrix (ECM) interactions are critical modulators of repair and regeneration. However, variability within individual cells of the same cell type and within the ECM microenvironment can lead to heterogeneous outcomes that may limit the reliable application of cell-biomaterial constructs in regenerative medicine. Understanding the origins of heterogeneity is critical to overcoming this challenge and requires measurement of cell-ECM interactions at the single cell level. There are four core biophysical modules that cells employ to interact with their surrounding ECM: protrusion, adhesion, contractility, and matrix remodeling. Conventional approaches measure these interactions in separate experiments on… More >

  • Open Access

    ARTICLE

    A MPTCP Scheduler for Web Transfer

    Wenjun Yang1, Pingping Dong1,2,*, Wensheng Tang1, Xiaoping Lou1, Hangjun Zhou3, Kai Gao4, Haodong Wang5

    CMC-Computers, Materials & Continua, Vol.57, No.2, pp. 205-222, 2018, DOI:10.32604/cmc.2018.03726

    Abstract Multipath TCP (MPTCP) is the most significant extension of TCP that enables transmission via multiple paths concurrently to improve the resource usage and throughput of long flows. However, due to the concurrent multiple transfer (CMT) in short flow trans-mission, the congestion window (cwnd) of each MPTCP subflow is too small and it may lead to timeout when a single lost packet cannot be recovered through fast retransmission. As a result, MPTCP has even worse performance for short flows compared to regular TCP. In this paper, we take the first step to analyze the main reason… More >

  • Open Access

    ARTICLE

    Effects of grazing on plant species diversity and carbon partitioning in semiarid rangelands of northeastern China

    Hu FL1,2, B Liu1,3, ZM Liu1,3, YT Fang1,3, CA Busso4

    Phyton-International Journal of Experimental Botany, Vol.84, No.1, pp. 209-221, 2015, DOI:10.32604/phyton.2015.84.209

    Abstract Grasslands are one of the most widespread landscapes worldwide, covering approximately one-fifth of the world’s land surface, where grazing is a common practice. How carbon storage responds to grazing in steppes remains poorly understood. We quantified the effects of grazing on community composition and species diversity, and carbon storage in two typical grasslands of northeastern China, one in Horqin and the other one in Hulunbeier. In both grasslands, grazing did not influence plant species diversity. However, it substantially decreased aboveground carbon by 31% and 54% in Horqin and Hulunbeier, respectively. Fenced and grazing treatments showed More >

  • Open Access

    ARTICLE

    THE EXPERIMENTAL AND NUMERICAL INVESTIGATION OF THE SOLIDIFICATION OF A POROUS CERAMIC CASTING

    Frantisek Kavickaa,*, Jana Dobrovskab, Karel Stranskya, Bohumil Sekaninaa, Josef Stetinaa

    Frontiers in Heat and Mass Transfer, Vol.3, No.2, pp. 1-9, 2012, DOI:10.5098/hmt.v3.2.3002

    Abstract Corundo-baddeleyit material (CBM) – EUCOR – is a heat- and wear-resistant material even at extreme temperatures. This article introduces an original numerical model of solidification and cooling of this material in a non-metallic mold. The second, cooperating model of chemical heterogeneity and its application on EUCOR samples prove that the applied method of measuring the chemical heterogeneity provides the detailed quantitative information on the material structure and makes it possible to analyze the solidification process. The verification of both numerical models was conducted on a real cast 350 x 200 x 400 mm block. More >

  • Open Access

    ARTICLE

    Effect of morphological heterogeneity of somatic embryos of Melia azedarach on conversion into plants

    SILVIA VILA, ANA GONZALEZ, HEBE REY AND LUIS MROGINSKI*

    BIOCELL, Vol.34, No.1, pp. 7-14, 2010, DOI:10.32604/biocell.2010.34.007

    Abstract Embryogenic cultures were initiated from immature Melia azedarach (Meliaceae) zigotic embryos. Explants were induced on Murashige and Skoog (1962) medium with 4.54 μM thidiazuron or 0.45 μM dichlorophenoxyacetic acid. After 6 weeks of culture on induction medium, somatic embryos were categorized in four morphological classes based on the presence of single or fused embryos and if they remained united or not to the original explant; that were evaluated histologically. The somatic embryos of every category were transferred, in groups or individually, on a 1/4 MS medium. Bipolar embryos, the more typically normal ones, had well defined More >

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