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  • Open Access

    PROCEEDINGS

    AI-Assisted Generative Inverse Design of Heterogeneous Meta-Biomaterials Based on TPMS for Biomimetic Tissue Engineering

    Xiaolong Zhu, Feng Chen, Yuntian Chen, Wei Zhu, Xiaoxiao Han*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.3, pp. 1-1, 2025, DOI:10.32604/icces.2025.012584

    Abstract Human tissues and organs exhibit not only intricate anatomical architectures but also spatially heterogeneous distributions of elastic modulus—for example, between cancellous and cortical bone, across the epidermis, dermis, and subcutaneous layers, and between healthy and fibrotic liver tissues. Conventional biomaterials often fail to replicate such mechanical heterogeneity, thereby limiting their capacity to recreate biomimetic physiological microenvironments essential for applications like tissue regeneration and disease modeling. Meta-biomaterials, artificially engineered through the rational structural design of continuous materials, have emerged as a promising class of materials owing to their highly tunable mechanical and biological properties. These attributes… More >

  • Open Access

    ARTICLE

    VHO Algorithm for Heterogeneous Networks of UAV-Hangar Cluster Based on GA Optimization and Edge Computing

    Siliang Chen1, Dongri Shan2,*, Yansheng Niu3

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5263-5286, 2025, DOI:10.32604/cmc.2025.067892 - 23 October 2025

    Abstract With the increasing deployment of Unmanned Aerial Vehicle-Hangar (UAV-H) clusters in dynamic environments such as disaster response and precision agriculture, existing networking schemes often struggle with adaptability to complex scenarios, while traditional Vertical Handoff (VHO) algorithms fail to fully address the unique challenges of UAV-H systems, including high-speed mobility and limited computational resources. To bridge this gap, this paper proposes a heterogeneous network architecture integrating 5th Generation Mobile Communication Technology (5G) cellular networks and self-organizing mesh networks for UAV-H clusters, accompanied by a novel VHO algorithm. The proposed algorithm leverages Multi-Attribute Decision-Making (MADM) theory combined… More >

  • Open Access

    ARTICLE

    Probabilistic Rock Slope Stability Assessment of Heterogeneous Pyroclastic Slopes Considering Collapse Using Monte Carlo Methodology

    Miguel A. Millán1,*, Rubén A. Galindo2, Fausto Molina‐Gómez1

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 2923-2941, 2025, DOI:10.32604/cmes.2025.069356 - 30 September 2025

    Abstract Volcanic terrains exhibit a complex structure of pyroclastic deposits interspersed with sedimentary processes, resulting in irregular lithological sequences that lack lateral continuity and distinct stratigraphic patterns. This complexity poses significant challenges for slope stability analysis, requiring the development of specialized techniques to address these issues. This research presents a numerical methodology that incorporates spatial variability, nonlinear material characterization, and probabilistic analysis using a Monte Carlo framework to address this issue. The heterogeneous structure is represented by randomly assigning different lithotypes across the slope, while maintaining predefined global proportions. This contrasts with the more common approach… More >

  • Open Access

    ARTICLE

    Mobility-Aware Edge Caching with Transformer-DQN in D2D-Enabled Heterogeneous Networks

    Yiming Guo, Hongyu Ma*

    CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3485-3505, 2025, DOI:10.32604/cmc.2025.067590 - 23 September 2025

    Abstract In dynamic 5G network environments, user mobility and heterogeneous network topologies pose dual challenges to the effort of improving performance of mobile edge caching. Existing studies often overlook the dynamic nature of user locations and the potential of device-to-device (D2D) cooperative caching, limiting the reduction of transmission latency. To address this issue, this paper proposes a joint optimization scheme for edge caching that integrates user mobility prediction with deep reinforcement learning. First, a Transformer-based geolocation prediction model is designed, leveraging multi-head attention mechanisms to capture correlations in historical user trajectories for accurate future location prediction.… More >

  • Open Access

    ARTICLE

    Second-Life Battery Energy Storage System Capacity Planning and Power Dispatch via Model-Free Adaptive Control-Embedded Heuristic Optimization

    Chuan Yuan1, Chang Liu2,3, Shijun Chen1, Weiting Xu2,3, Jing Gou1, Ke Xu2,3, Zhengbo Li4,*, Youbo Liu4

    Energy Engineering, Vol.122, No.9, pp. 3573-3593, 2025, DOI:10.32604/ee.2025.067785 - 26 August 2025

    Abstract The increasing penetration of second-life battery energy storage systems (SLBESS) in power grids presents substantial challenges to system operation and control due to the heterogeneous characteristics and uncertain degradation patterns of repurposed batteries. This paper presents a novel model-free adaptive voltage control-embedded dung beetle-inspired heuristic optimization algorithm for optimal SLBESS capacity configuration and power dispatch. To simultaneously address the computational complexity and ensure system stability, this paper develops a comprehensive bilevel optimization framework. At the upper level, a dung beetle optimization algorithm determines the optimal SLBESS capacity configuration by minimizing total lifecycle costs while incorporating… More >

  • Open Access

    ARTICLE

    CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA

    Yuhan Wang, Yimei Meng, Wanqiu Xia, Yusen Liang, Yaru Wang, Peiling Li*, Lei Fang*

    Oncology Research, Vol.33, No.8, pp. 2141-2159, 2025, DOI:10.32604/or.2025.064367 - 18 July 2025

    Abstract Background: Ovarian cancer (OC) is a representative malignancy of the female reproductive system, with a poor prognosis. Long non-coding RNAs (lncRNAs) crucially affect tumor development. This study aimed to identify lncRNAs that potentially participated in OC. Methods: LncRNA expression in cells and tissues was quantified using reverse transcription-quantitative PCR, while fluorescence in situ hybridization determined their cellular localization. Various in vitro assays, together with a mouse xenograft model, were employed to elucidate the function of CYMP antisense RNA 1 (CYMP-AS1) in OC. The molecular mechanisms underlying CYMP-AS1 regulation were investigated through RNA pull-down and immunoprecipitation assays, immunofluorescence… More > Graphic Abstract

    CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA

  • Open Access

    ARTICLE

    Intelligent Management of Resources for Smart Edge Computing in 5G Heterogeneous Networks Using Blockchain and Deep Learning

    Mohammad Tabrez Quasim1,*, Khair Ul Nisa1, Mohammad Shahid Husain2, Abakar Ibraheem Abdalla Aadam1, Mohammed Waseequ Sheraz1, Mohammad Zunnun Khan1

    CMC-Computers, Materials & Continua, Vol.84, No.1, pp. 1169-1187, 2025, DOI:10.32604/cmc.2025.062989 - 09 June 2025

    Abstract Smart edge computing (SEC) is a novel paradigm for computing that could transfer cloud-based applications to the edge network, supporting computation-intensive services like face detection and natural language processing. A core feature of mobile edge computing, SEC improves user experience and device performance by offloading local activities to edge processors. In this framework, blockchain technology is utilized to ensure secure and trustworthy communication between edge devices and servers, protecting against potential security threats. Additionally, Deep Learning algorithms are employed to analyze resource availability and optimize computation offloading decisions dynamically. IoT applications that require significant resources… More >

  • Open Access

    ARTICLE

    Enhanced Practical Byzantine Fault Tolerance for Service Function Chain Deployment: Advancing Big Data Intelligence in Control Systems

    Peiying Zhang1,2,*, Yihong Yu1,2, Jing Liu3, Chong Lv1,2, Lizhuang Tan4,5, Yulin Zhang6,7,8

    CMC-Computers, Materials & Continua, Vol.83, No.3, pp. 4393-4409, 2025, DOI:10.32604/cmc.2025.064654 - 19 May 2025

    Abstract As Internet of Things (IoT) technologies continue to evolve at an unprecedented pace, intelligent big data control and information systems have become critical enablers for organizational digital transformation, facilitating data-driven decision making, fostering innovation ecosystems, and maintaining operational stability. In this study, we propose an advanced deployment algorithm for Service Function Chaining (SFC) that leverages an enhanced Practical Byzantine Fault Tolerance (PBFT) mechanism. The main goal is to tackle the issues of security and resource efficiency in SFC implementation across diverse network settings. By integrating blockchain technology and Deep Reinforcement Learning (DRL), our algorithm not… More >

  • Open Access

    REVIEW

    Survey on AI-Enabled Resource Management for 6G Heterogeneous Networks: Recent Research, Challenges, and Future Trends

    Hayder Faeq Alhashimi1, Mhd Nour Hindia1, Kaharudin Dimyati1,*, Effariza Binti Hanafi1, Feras Zen Alden2, Faizan Qamar3, Quang Ngoc Nguyen4,5,*

    CMC-Computers, Materials & Continua, Vol.83, No.3, pp. 3585-3622, 2025, DOI:10.32604/cmc.2025.062867 - 19 May 2025

    Abstract The forthcoming 6G wireless networks have great potential for establishing AI-based networks that can enhance end-to-end connection and manage massive data of real-time networks. Artificial Intelligence (AI) advancements have contributed to the development of several innovative technologies by providing sophisticated specific AI mathematical models such as machine learning models, deep learning models, and hybrid models. Furthermore, intelligent resource management allows for self-configuration and autonomous decision-making capabilities of AI methods, which in turn improves the performance of 6G networks. Hence, 6G networks rely substantially on AI methods to manage resources. This paper comprehensively surveys the recent… More >

  • Open Access

    ARTICLE

    Coupling Magneto-Electro-Elastic Multiscale Finite Element Method for Transient Responses of Heterogeneous MEE Structures

    Xiaolin Li1, Xinyue Li1, Liming Zhou2,*, Hangran Yang1, Xiaoqing Yuan1

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 3821-3841, 2025, DOI:10.32604/cmc.2025.059937 - 06 March 2025

    Abstract Magneto-electro-elastic (MEE) materials are widely utilized across various fields due to their multi-field coupling effects. Consequently, investigating the coupling behavior of MEE composite materials is of significant importance. The traditional finite element method (FEM) remains one of the primary approaches for addressing such issues. However, the application of FEM typically necessitates the use of a fine finite element mesh to accurately capture the heterogeneous properties of the materials and meet the required computational precision, which inevitably leads to a reduction in computational efficiency. To enhance the computational accuracy and efficiency of the FEM for heterogeneous… More >

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