Sergio Henrique Gonçalves Motta¹, Ana Paula Ramos Soares¹, Juliana Campos Hasse Fernandes², Gustavo Vicentis Oliveira Fernandes^2,3,*

Journal of Renewable Materials, Vol.12, No.1, pp. 131-148, 2024, DOI:10.32604/jrm.2023.043940 - 23 January 2024

Abstract Bone biomaterials have been increasingly used to reconstruct maxillary atrophic ridges. Thus, the aim of this study was to evaluate bone reconstruction in the maxilla using a homologous cortico-cancellous FFB (lyophilized) graft and verify its reliability. Eight individuals were included from 2014 to 2018. The first surgery was performed to install homologous bone blocks in the maxilla. The period of the second intervention varied between 5 months and 15 days to 11 months (≈7.93 months). The biopsies were taken from the central region of the matured graft during the surgery for implant placement. All patients… More >

Joshua S. Jue^1,2, Tulay Koru-Sengul^3,4, Kevin J. Moore^2,3, Feng Miao², Mahmoud Alameddine¹, Bruno Nahar¹, Sanoj Punnen¹, Dipen J. Parekh^1,4, Chad R. Ritch¹, Mark L. Gonzalgo^1,4

Canadian Journal of Urology, Vol.25, No.1, pp. 9179-9185, 2018

Abstract Introduction: To investigate the impact of perioperative factors on overall survival among patients with histologic variants of bladder cancer treated with radical cystectomy.
Materials and methods: The National Cancer Data Base (NCDB) was utilized to identify patients diagnosed with muscle-invasive bladder cancer (cT2–T4, N0, M0) from 2004 to 2013. Variant histology bladder cancers—including non-mucinous adenocarcinoma, mucinous/signet ring adenocarcinoma, micropapillary urothelial carcinoma, small cell carcinoma, and squamous cell carcinoma—were compared to urothelial carcinoma with respect to overall survival. Adjusted hazard ratios (aHR) and 95% confidence intervals (CI) were calculated using a multivariable Cox regression model to examine factors… More >

Jamil S. Syed¹, Cayce B. Nawaf¹, James Rosoff¹, Campbell Bryson¹, Kevin A. Nguyen¹, Alfredo Suarez-Sarmiento¹, Maria Serrano², Adam S. Kibel⁴, Peter Humphrey³, Brian Shuch¹, Adebowale J. Adeniran³

Canadian Journal of Urology, Vol.24, No.2, pp. 8759-8764, 2017

Abstract Introduction: Evidence has demonstrated that tumor size is related to adverse oncologic outcomes in small renal tumors (≤ 4 cm). We evaluated the association of adverse pathologic features (APF) with tumor size and survival in patients with a small renal mass (SRM).
Materials and methods: We retrospectively reviewed the pathologic characteristics of 380 surgically resected SRMs from a single institution. APFs included lymphovascular invasion, coagulative necrosis, sarcomatoid/rhabdoid features, papillary type II histology, and perinephric fat/renal sinus invasion. The number and type of APFs were compared with tumor size. Survival analysis was performed using the Kaplan-Meier method.
Results: There… More >

Dayron Rodríguez¹, Kristine M. Cornejo², Peter M. Sadow², Yahir Santiago-Lastra¹, Adam S. Feldman¹

Canadian Journal of Urology, Vol.22, No.3, pp. 7830-7833, 2015

Abstract Myopericytoma is a low grade spindle cell neoplasm largely occurring in skin. We describe the first reported case of a penile myopericytoma. Histologically, the penile tumor was composed of a perivascular proliferation of tumor cells with ovoid shaped nuclei and abundant eosinophilic cytoplasm. Immunohistochemically, the tumor was reactive for markers of smooth muscle differentiation and vascular differentiation. The tumor was noted to be negative for BRAF by immunohistochemistry and wild-type upon gene sequencing using SnaPshot. Our finding serves to expand the anatomical distribution of myopericytoma and broadens the spectrum of primary mesenchymal neoplasms that may More >

Yachao Zhang¹, Kazim R. Chohan^2,3, Steve K. Landas^3,4, Jay E. Reeder⁴, J.C. Trussell⁴

Canadian Journal of Urology, Vol.21, No.5, pp. 7475-7478, 2014

Abstract Introduction: In obstructive azoospermia, choosing a sperm retrieval method for intracytoplasmic sperm injection (ICSI) depends on the preference and expertise of both the urologist and the reproductive endocrinologist. Generally, a percutaneous epididymal sperm aspiration (PESA) is attempted first. Not uncommonly, multiple PESA's are necessary. This study utilizes a rat model to provide an understanding of sperm parameter and histological changes resulting from repetitive PESA procedures.
Materials and methods: A cohort of 30 male Wistar rats of reproductive age (68-73 days) was divided into three groups of 10 (G1-G3). All three groups underwent a left epididymal head… More >

James Lin, Michael Whalen, Dara Holder, Gregory Hruby, G. Joel DeCastro, James McKiernan

Canadian Journal of Urology, Vol.20, No.2, pp. 6690-6695, 2013

Abstract Introduction: We examined the effects of neoadjuvant chemotherapy (NC) in the treatment of muscle invasive urothelial carcinoma of the bladder in those with mixed histology (MH) versus those with pure urothelial carcinoma (UC).
Materials and methods: Between 2000 and 2012, 195 patients were identified with clinical stage T2–T4, N0–Nx, M0–Mx UCB who had either NC (± radical cystectomy) (n = 63) or radical cystectomy (RC) alone (n = 132). Tumors were classified as either pure UC or MH. Endpoints included downstaging to pT0 and overall survival. Multivariable Cox regression and the Kaplan-Meier method were used to estimate… More >

Daniel J. Canter

Canadian Journal of Urology, Vol.20, No.3, pp. 6798-6798, 2013

Abstract This article has no abstract. More >

Ryan P. Kopp^1,2, Lejla Aganovic^3,4, Kerrin L. Palazzi¹, Fiona H. Cassidy^3,4, Kyoko Sakamoto^1,2, Ithaar H. Derweesh^1,2

Canadian Journal of Urology, Vol.20, No.3, pp. 6790-6797, 2013

Abstract Introduction: To further elucidate potential patterns of contrast enhancement for renal neoplasm subtypes, we investigated the utility of a contrast washout formula to differentiate renal tumor histology after multiphase computerized tomography (CT).
Materials and methods: A single-center retrospective cohort study of 163 patients with multiphase CT for renal masses obtained from October 2007 to July 2012. Pathology confirmed clear cell renal cell carcinoma (CC-RCC; n = 92), papillary (Pa-RCC; n = 43), chromophobe (Ch-RCC; n = 6), oncocytoma (OC; n = 11), or angiomyolipoma (AML; n = 11) histology. Two radiologists in consensus, blinded to histology, recorded… More >

SILVIA VILA, ANA GONZALEZ, HEBE REY AND LUIS MROGINSKI*

BIOCELL, Vol.34, No.1, pp. 7-14, 2010, DOI:10.32604/biocell.2010.34.007

Abstract Embryogenic cultures were initiated from immature Melia azedarach (Meliaceae) zigotic embryos. Explants were induced on Murashige and Skoog (1962) medium with 4.54 μM thidiazuron or 0.45 μM dichlorophenoxyacetic acid. After 6 weeks of culture on induction medium, somatic embryos were categorized in four morphological classes based on the presence of single or fused embryos and if they remained united or not to the original explant; that were evaluated histologically. The somatic embryos of every category were transferred, in groups or individually, on a 1/4 MS medium. Bipolar embryos, the more typically normal ones, had well defined More >

David E. Rapp¹, Lambda P. Msezane¹, W. Stuart Reynolds¹, Tamara L. Lotan², Piotr Obara¹, R. Corey O’Connor³, Jerome B. Taxy², Glenn S. Gerber¹, Gregory P. Zagaja¹

Canadian Journal of Urology, Vol.16, No.1, pp. 4484-4489, 2009

Abstract Objectives: We sought to evaluate the ability of biopsy core recutting to increase cancer detection in patients with high grade prostatic intraepithelial neoplasia (HGPIN).
Methods: This prospective study encompasses all patients undergoing 12 core TRUS guided prostate biopsy between February 2004 and January 2007. In patients with HGPIN on initial biopsy, the paraffin blocks were resampled for cancer by additional deeper levels per core. Additional analysis was performed in the patients with HGPIN in order to detect whether significant differences in prebiopsy variables were associated with patients subsequently found to have benign versus carcinoma on recutting. Last,… More >