Yanmei Li1,*, Jinghong Tang1, Weiwu Ding1, Jian Luo2, Naveed Ahmad3, Rajesh Kumar4
CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 713-733, 2024, DOI:10.32604/cmc.2023.046872
Abstract Alzheimer’s disease (AD) is a complex, progressive neurodegenerative disorder. The subtle and insidious onset of its pathogenesis makes early detection of a formidable challenge in both contemporary neuroscience and clinical practice. In this study, we introduce an advanced diagnostic methodology rooted in the Med-3D transfer model and enhanced with an attention mechanism. We aim to improve the precision of AD diagnosis and facilitate its early identification. Initially, we employ a spatial normalization technique to address challenges like clarity degradation and unsaturation, which are commonly observed in imaging datasets. Subsequently, an attention mechanism is incorporated to selectively focus on the salient… More >