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  • Open Access

    ARTICLE

    Analysis of risk factors for MRI-invisible prostate cancer—the significance of AGGF1 immunohistochemical detection and PSAD

    Jingcheng Lyu1,2,#, Ruiyu Yue1,2,#, Ye Tian1,2,*, Boyu Yang1,2,*

    Canadian Journal of Urology, Vol.33, No.2, pp. 361-375, 2026, DOI:10.32604/cju.2026.074814 - 20 April 2026

    Abstract Objectives: Patients with a multi-parameter magnetic resonance imaging (mpMRI) prostate imaging report and data system (PI-RADS) score ≤ 3, but with clinically significant prostate cancer (CSPCa) detected by biopsy, are termed MRI-Invisible prostate cancer (MRI(-)PCa). This study aims to explore risk factors for MRI(-)PCa and identify immunohistochemical indicators with predictive significance. Methods: A retrospective analysis was conducted on 376 patients with PI-RADS score ≤ 3 who underwent 24-needle systematic prostate biopsy at Beijing Friendship Hospital, Capital Medical University (January 2015 to October 2025). Clinical data, imaging data, and Angiogenic factor with G and FHA domain… More >

  • Open Access

    ARTICLE

    Association between the severity of acute renal colic episodes and clinical, laboratory, and imaging parameters

    Kai Dang1,2,#, Teng Cui1,2,#, Yongan Zhou1,2, Jiayuan Ji1,2, Yang Yang1,2, Xiangyu Wang1,2, Jing Xiao1,2,*

    Canadian Journal of Urology, Vol.33, No.2, pp. 403-415, 2026, DOI:10.32604/cju.2026.068291 - 20 April 2026

    Abstract Objectives: Although renal colic is a well-known acute manifestation of urolithiasis, the relationship between its pain severity and a range of clinical parameters has not been clearly established by comprehensive studies. This study aimed to construct and validate a simple and accurate clinical nomogram for predicting the occurrence of more intense acute renal colic (ARC) in patients with urolithiasis. Methods: The development and validation of the prediction model followed the reporting standards outlined in the TRIPOD checklist. A retrospective analysis was conducted on 285 patients who visited the Department of Urology at Beijing Friendship Hospital,… More >

  • Open Access

    ARTICLE

    Position-Wise Attention-Enhanced Vision Transformer for Diabetic Retinopathy Grading

    Yan-Hao Huang*, Yu-Tse Huang

    CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.076800 - 09 April 2026

    Abstract Diabetic Retinopathy (DR) is a common microvascular complication of diabetes that progressively damages the retinal blood vessels and, without timely treatment, can lead to irreversible vision loss. In clinical practice, DR is typically diagnosed by ophthalmologists through visual inspection of fundus images, a process that is time-consuming and prone to inter- and intra-observer variability. Recent advances in artificial intelligence, particularly Convolutional Neural Networks (CNNs) and Transformer-based models, have shown strong potential for automated medical image classification and decision support. In this study, we propose a Position-Wise Attention-Enhanced Vision Transformer (PWAE-ViT), which integrates a positional attention… More >

  • Open Access

    ARTICLE

    An Isothermal Surface Imaging and Transfer Learning Framework for Fast Isothermal Surface Prediction and 3D Temperature Field Reconstruction in Metal Additive Manufacturing

    Zhidong Wang, Yanping Lian*, Mingjian Li, Jiawei Chen, Ruxin Gao

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.3, 2026, DOI:10.32604/cmes.2026.078312 - 30 March 2026

    Abstract Metal additive manufacturing (AM) technology has promising applications across many fields due to its near-net-shape advantages. The quality of the as-built component is closely linked to the temperature evolution during the metal AM process, which exhibits strong nonlinearities, localized high gradients, and rapid cooling rates. Therefore, real-time prediction of the temperature field is essential for effective online process control to achieve high fabrication quality, which poses surprising challenges for numerical methods, as traditional methods suffer from the inherent time-consuming nature of fine time-space discretizations. In this study, we proposed an isothermal surface imaging and transfer… More >

  • Open Access

    ARTICLE

    A Deep Learning- and AI-Enhanced Telecentric Vision Framework for Automated Imaging-to-CAD Reconstruction

    Toa Saito1, Kantawatchr Chaiprabha2, Kosuke Takano1, Gridsada Phanomchoeng2, Ratchatin Chancharoen2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.3, 2026, DOI:10.32604/cmes.2026.077356 - 30 March 2026

    Abstract This paper presents an automated imaging-to-CAD reconstruction system that combines telecentric vision and deep learning for high-accuracy digital reconstruction of printed circuit boards (PCBs). The framework integrates a telecentric camera with a Cartesian scanning platform to capture distortion-free, high-resolution PCB images, which are stitched into a single orthographic composite. A YOLO-based detection model, trained on a dataset of 270 PCB images across 23 component classes with data augmentation, identifies and localizes electronic components with a mean average precision of 0.932. Detected components are automatically matched to corresponding 3D CAD models from a part library and More >

  • Open Access

    REVIEW

    A Comprehensive Review and Algorithmic Analysis of Histogram-Based Contrast Enhancement Techniques for Medical Imaging

    Saira Ali Bhatti1, Maqbool Khan2,*, Arshad Ahmad3, Muhammad Shahid Anwar4, Leila Jamel5, Aisha M. Mashraqi6, Wadee Alhalabi7,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.3, 2026, DOI:10.32604/cmes.2026.074688 - 30 March 2026

    Abstract Medical imaging is essential in modern health care, allowing accurate diagnosis and effective treatment planning. These images, however, often demonstrate low contrast, noise, and brightness distortion that reduce their diagnostic reliability. This review presents a structured and comprehensive analysis of advanced histogram equalization (HE)-based techniques for medical image enhancement. Our review methodology encompasses: (1) classical HE approaches and related limitations in medical domains; (2) adaptive schemes like Adaptive Histogram Equalization (AHE) and Contrast Limited Adaptive Histogrma Equalization (CLAHE) and their advance variants; (3) brightness-preserving schemes like BBHE and MMBEBHE and related algorithms; (4) dynamic and More > Graphic Abstract

    A Comprehensive Review and Algorithmic Analysis of Histogram-Based Contrast Enhancement Techniques for Medical Imaging

  • Open Access

    ARTICLE

    Is postoperative routine thoracic imaging necessary to detect thoracic complications in patients undergoing supracostal mini percutaneous nephrolithotomy (m-PCNL) surgery?

    Abdullah Esmeray, Huseyin Burak Yazili*, Mucahit Gelmis, Nazim Furkan Gunay, Caglar Dizdaroglu, Faruk Ozgor, Yasar Pazir, Ufuk Caglar

    Canadian Journal of Urology, Vol.33, No.1, pp. 165-171, 2026, DOI:10.32604/cju.2025.069657 - 28 February 2026

    Abstract Objectives: Supracostal access during percutaneous nephrolithotomy (PCNL) increases the risk of pulmonary complications. Although routine postoperative thoracic imaging is commonly performed to detect these events, its clinical necessity remains controversial. This study aimed to assess the necessity of routine postoperative thoracic imaging for detecting pulmonary complications in patients undergoing supracostal mini percutaneous nephrolithotomy (m-PCNL) surgery. Methods: A retrospective analysis was conducted on data from patients who underwent supracostal m-PCNL between 2017 and 2022 in a tertiary center. Excluding patients under 18, with kidney/skeletal anomalies, or active thoracic disease, 112 eligible patients were included. Patients were… More >

  • Open Access

    CASE REPORT

    Double blind-ending ureter: diagnostic challenges and robotic-assisted surgical management—case report

    Marco Di Mitri1,2,*, Edoardo Collautti1,2, Cristian Bisanti3, Andrea Zulli1, Alberto Mantovani1, Annalisa Di Carmine3, Michelangelo Baldazzi4, Roberto Lo Piccolo1, Riccardo Coletta1,5, Lorenzo Masieri6, Mario Lima3

    Canadian Journal of Urology, Vol.33, No.1, pp. 185-192, 2026, DOI:10.32604/cju.2025.067303 - 28 February 2026

    Abstract Background: Double blind-ending ureter (DBU) is an extremely rare congenital anomaly involving a duplicated ureter with no connection to the renal pelvis or bladder, making diagnosis difficult. Case Description: A 10-year-old girl presented with recurrent abdominal pain and ultrasound evidence of left hydroureteronephrosis. Magnetic resonance imaging (MRI) and three-dimensional (3D) reconstruction revealed a 30 cm blind-ending ureter. Robotic-assisted excision (Da Vinci Xi) was performed safely, preserving adjacent structures. Histology confirmed a nonfunctional ureteral remnant. Conclusions: DBU is a rare duplication variant. Advanced imaging and robotic surgery are essential for accurate diagnosis and effective, minimally invasive treatment. More >

  • Open Access

    ARTICLE

    Optimized Deep Learning Framework for Robust Detection of GAN-Induced Hallucinations in Medical Imaging

    Jarrar Amjad1, Muhammad Zaheer Sajid2, Mudassir Khalil3, Ayman Youssef4, Muhammad Fareed Hamid5, Imran Qureshi6,*, Haya Aldossary7, Qaisar Abbas6

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.2, 2026, DOI:10.32604/cmes.2026.073473 - 26 February 2026

    Abstract Generative Adversarial Networks (GANs) have become valuable tools in medical imaging, enabling realistic image synthesis for enhancement, augmentation, and restoration. However, their integration into clinical workflows raises concerns, particularly the risk of subtle distortions or hallucinations that may undermine diagnostic accuracy and weaken trust in AI-assisted decision-making. To address this challenge, we propose a hybrid deep learning framework designed to detect GAN-induced artifacts in medical images, thereby reinforcing the reliability of AI-driven diagnostics. The framework integrates low-level statistical descriptors, including high-frequency residuals and Gray-Level Co-occurrence Matrix (GLCM) texture features, with high-level semantic representations extracted from… More >

  • Open Access

    ARTICLE

    A Hybrid Vision Transformer with Attention Architecture for Efficient Lung Cancer Diagnosis

    Abdu Salam1, Fahd M. Aldosari2, Donia Y. Badawood3, Farhan Amin4,*, Isabel de la Torre5,*, Gerardo Mendez Mezquita6, Henry Fabian Gongora6

    CMC-Computers, Materials & Continua, Vol.87, No.1, 2026, DOI:10.32604/cmc.2025.073342 - 10 February 2026

    Abstract Lung cancer remains a major global health challenge, with early diagnosis crucial for improved patient survival. Traditional diagnostic techniques, including manual histopathology and radiological assessments, are prone to errors and variability. Deep learning methods, particularly Vision Transformers (ViT), have shown promise for improving diagnostic accuracy by effectively extracting global features. However, ViT-based approaches face challenges related to computational complexity and limited generalizability. This research proposes the DualSet ViT-PSO-SVM framework, integrating a ViT with dual attention mechanisms, Particle Swarm Optimization (PSO), and Support Vector Machines (SVM), aiming for efficient and robust lung cancer classification across multiple… More >

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