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  • Open Access

    ARTICLE

    Intermediate and Long-Term Follow-Up of Transcatheter Closure of Congenital Coronary Cameral Fistulas in Infants and Children: Experience from a Single Center

    Yifan Li1, Zewen Chen2, Yumei Xie1, Shushui Wang1, Zhiwei Zhang1,*

    Congenital Heart Disease, Vol.18, No.4, pp. 413-430, 2023, DOI:10.32604/chd.2023.029848 - 15 September 2023

    Abstract Background: Limited data are available regarding intermediate and long-term outcomes of transcatheter closure (TCC) of coronary cameral fistulas (CCFs) in the pediatric patients. Methods: All pediatric patients diagnosed with CCFs who were scheduled to undergo TCC between 2005 and 2019 were retrospectively enrolled in the study. Results: A total of 66 patients (median age: 3.93 years, median weight: 15 kg) underwent attempted TCC of CCFs. Immediate successful device implantation was achieved in 62 patients, and immediate complete occlusion was achieved in 44 patients (44/62%, 71.0%). The closure procedure was waived in 2 patients due to anatomical factors.… More >

  • Open Access

    REVIEW

    Transcatheter Closure vs. Surgical Ligation in Preterm Infants with Patent Ductus Arteriosus: A Systematic Review and Meta-Analysis

    Rohan Suresh Daniel1,2, Georgia K. Schmidt1,2, Hayato Nakanishi1,2, Karen Smayra1,2, Mariah N. Mascara1,2, Dilip K. Vankayalapati1,2, Reem H. Matar1,2,3, Christian A. Than1,2,4, George Shiakos5, Ioannis Tzanavaros2,5,*

    Congenital Heart Disease, Vol.18, No.2, pp. 245-265, 2023, DOI:10.32604/chd.2023.027596 - 15 March 2023

    Abstract Background: Persistent patent ductus arteriosus (pPDA) is a common condition in preterm infants. This meta-analysis aimed to assess the safety and efficacy of transcatheter closure (TC) when compared to surgical ligation (SL) in preterm infants with pPDA. Methods: A literature search of Ovid Cochrane Library, Medline, Embase, Epub, Scopus, PMC Preprints, and was conducted from inception to May 06, 2022. Eligible studies reported infants diagnosed with pPDA born at ≤2000 g birth weight or at ≤37 weeks’ who underwent TC or SL as treatment. This review was registered in PROSPERO (CRD42022325944). Results: From 97 studies screened, 8… More >

  • Open Access

    ARTICLE

    Explainable AI Enabled Infant Mortality Prediction Based on Neonatal Sepsis

    Priti Shaw1, Kaustubh Pachpor2, Suresh Sankaranarayanan3,*

    Computer Systems Science and Engineering, Vol.44, No.1, pp. 311-325, 2023, DOI:10.32604/csse.2023.025281 - 01 June 2022

    Abstract Neonatal sepsis is the third most common cause of neonatal mortality and a serious public health problem, especially in developing countries. There have been researches on human sepsis, vaccine response, and immunity. Also, machine learning methodologies were used for predicting infant mortality based on certain features like age, birth weight, gestational weeks, and Appearance, Pulse, Grimace, Activity and Respiration (APGAR) score. Sepsis, which is considered the most determining condition towards infant mortality, has never been considered for mortality prediction. So, we have deployed a deep neural model which is the state of art and performed More >

  • Open Access

    ARTICLE

    Incidence and Related Risk Factors of Junctional Ectopic Tachycardia in Infants after Cardiac Surgery for Congenital Heart Disease

    Jae Hee Seol1,4,#, Se Yong Jung1,#, Jae Young Choi1, Han Ki Park2, Young Hwan Park2, Nam Kyun Kim1,3,*

    Congenital Heart Disease, Vol.17, No.5, pp. 569-578, 2022, DOI:10.32604/chd.2022.018436 - 06 September 2022

    Abstract Objective: Junctional ectopic tachycardia is common after cardiac surgery for congenital heart disease. However, its incidence and related risk factors in infants after cardiac surgery are not well known. The objective of this study was to determine the overall incidence and related risk factors for junctional ectopic tachycardia in neonates and infants. Methods: We enrolled a total of 271 patients aged <1 year who underwent open cardiac surgery at Severance Cardiovascular Hospital from January 2018 to December 2020. Exclusion criteria were immediate postoperative mortality, other arrhythmias detected in the perioperative period, and prematurity. Result: The overall incidence of… More >

  • Open Access

    ARTICLE

    Minimally Invasive Surgical Technique in Double Aortic Arch with Distal Atretic Left-Side in Infant: From a Single-Surgeon Clinical Experience

    Qi Liu, Shoujun Li, Zhongdong Hua*

    Congenital Heart Disease, Vol.17, No.5, pp. 533-539, 2022, DOI:10.32604/chd.2022.020496 - 06 September 2022

    Abstract Background: Double aortic arch (DAA) with distal left-sided aortic arch atresia (LAAA) can form complete vascular ring by ligamentum connection. We aimed to introduce an uncommon DAA-LAAA diagnosis and treatment by the minimally invasive surgical technique (MIST). Methods: We retrospectively reviewed 7 cases of DAA-LAAA that were treated from January 2017 to July 2021. All infant patients underwent surgical repair by minimally invasive surgical technique. Mean follow-up was 14.43 months (range, 5–21 months). Results: There were seven patients with DAA-LAAA, including six males and one female. Median age was 19.29 months (range, 9.0–29.0 months). Median weight was… More > Graphic Abstract

    Minimally Invasive Surgical Technique in Double Aortic Arch with Distal Atretic Left-Side in Infant: From a Single-Surgeon Clinical Experience

  • Open Access

    CASE REPORT

    Life Threatening Broad QRS Tachycardia in an Infant with Conduction Disorder and SCN5A Mutation

    Elio Caruso1,*, Silvia Farruggio1, Alfredo Di Pino1, Paolo Guccione1, Mohammadrafie Khorgami2

    Congenital Heart Disease, Vol.17, No.5, pp. 551-556, 2022, DOI:10.32604/chd.2022.023711 - 06 September 2022

    Abstract We present the case of an infant admitted to our department for a rapid broad complex tachycardia and cardiovascular collapse. The patient was submitted to genetic testing because of a conduction defect at baseline ECG and family history of gene mutation. A new SCN5A gene mutation variant was found leading to diagnosis of sodium-channel dysfunction arrhythmia. More > Graphic Abstract

    Life Threatening Broad QRS Tachycardia in an Infant with Conduction Disorder and <i>SCN5A</i> Mutation

  • Open Access

    ARTICLE

    Neurodevelopmental in Relation to Breastfeeding–Experiences among Hungarian Preterm Infants at 12 Months of Corrected Age: Empirical Study

    Anna Szabina Szele1,*, Beáta Erika Nagy2

    International Journal of Mental Health Promotion, Vol.24, No.5, pp. 699-709, 2022, DOI:10.32604/ijmhp.2022.021809 - 27 July 2022

    Abstract Preterm and low birth weight infants are at higher risk of neurodevelopmental outcomes; breastfeeding offers several beneficial aspects for them. This study aimed to describe the average neurodevelopmental outcomes of preterm infants and examine the associations between neurodevelopment and breastfeeding among Hungarian preterm infants at 12 months of corrected age. 154 preterm infants with low birth weight (<2500 g) and their mothers were participated in this study. Bayley-III Screening Test (Bayley Scales of Infant and Toddler Development Screening Test, Third Edition) was administered to measure the cognitive, language and motor skills of infants; breastfeeding data was… More >

  • Open Access

    ARTICLE

    Perpulmonary Device Closure of Patent Ductus Arteriosus with Minimum Diameter More Than 4 mm in Infants

    Shibin Sun1,#, Geoffrey J. Changwe1,2,#, Zeeshan Farhaj1, Hongxin Li1,*, Yuekun Sun1, Zhongzheng Kong1

    Congenital Heart Disease, Vol.17, No.4, pp. 437-445, 2022, DOI:10.32604/chd.2022.019943 - 04 July 2022

    Abstract Background: Closure of large patent ductus arteriosus (PDA) in older children has been accomplished using surgical and percutaneous techniques with remarkable outcomes. However, outcomes amongst infants have been variable with several drawbacks. Here we describe a novel minimally invasive technique, a product of mini-thoracotomy and traditional percutaneous technique skills, accomplished exclusively under echocardiography guidance. Methods: Symptomatic infants with a significant left-to-right shunt from PDA measuring more than 4 mm were selected. The symptoms were varying degrees of tachypnea, tachycardia, heart failure, failure to thrive, recurrent respiratory tract infections, or intensive care unit treatment for a longer duration.… More >

  • Open Access

    ARTICLE

    Analysis of specific lipid metabolites in cord blood of patients with gestational diabetes mellitus

    YANQIU LI#,*, CHENJUN HAO#, WEIYI CHEN, QINGJU MENG

    BIOCELL, Vol.46, No.6, pp. 1565-1573, 2022, DOI:10.32604/biocell.2022.018347 - 07 February 2022

    Abstract This work aimed to clarify the interaction between the fetus and pregnant patients with gestational diabetes mellitus (GDM), the lipid metabolomics analysis of the fetal umbilical cord blood of GDM patients and normal pregnant women were performed to screen out the specific lipid metabolites for pathogenesis of GDM. From 2019–2020, 21 patients with GDM and 22 normal pregnant women were enrolled in Hexian Memorial Hospital, Panyu District, Guangzhou. The general information such as weight, height, age, body mass index (BMI) before pregnancy were analyzed. Non-targeted metabonomic detection and analysis were performed in umbilical cord plasma… More >

  • Open Access

    REVIEW

    Ductus Arteriosus Stent Compared with Surgical Shunt for Infants with Ductal-Dependent Pulmonary Blood Flow: A Systematic Review and Meta-Analysis

    Sibao Wang, Silin Pan*, Gang Luo, Zhixian Ji, Na Liu

    Congenital Heart Disease, Vol.17, No.1, pp. 45-60, 2022, DOI:10.32604/CHD.2022.016332 - 26 October 2021

    Abstract The aim of this study was to perform a systematic review and meta-analysis to evaluate the safety and efficacy of ductus arteriosus stent (DAS) compared with surgical systemic-pulmonary artery shunt (SPS) in patients with ductal-dependent pulmonary blood flow. A literature search was conducted in PubMed, Embase, and the Cochrane Library databases from their inception to December 2020. Two reviewers independently screened the articles, evaluated the quality of the articles, and collected the data. Meta-analyses were conducted using fixed and random effects models. We used the I-square (I2 ) test to examine heterogeneity and the funnel plot… More >

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