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    ARTICLE

    Comprehensive Assessment of the Safety of Eucommia ulmoides Leaf Extract for Consumption as a Traditional Chinese Health Food

    Huiling Fu1, Mijun Peng2, Qiuwen Tang2, Haojun Liang2, Yanli Liang2, Jiali Fang2,*, Xuesong Wang2,*

    Journal of Renewable Materials, Vol.11, No.7, pp. 3091-3114, 2023, DOI:10.32604/jrm.2023.026689

    Abstract To ensure the export quality of Eucommia ulmoides leaf extract (ELE) and facilitate E. ulmoides leaf inclusion in the directory of traditional Chinese health foods, an overall safety assessment of ELE was performed, including genotoxicity and long-term toxicity, according to the national food safety standards of China. No variations in the reverse mutation number of the nominal bacterial strains were observed under ELE treatment in comparison with the solvent control. Additionally, the micronucleus rates of in vivo mammalian erythrocytes and in vitro mammalian cells under ELE treatment were equivalent to or significantly lower than those of the solvent control. The… More > Graphic Abstract

    Comprehensive Assessment of the Safety of <i>Eucommia ulmoides</i> Leaf Extract for Consumption as a Traditional Chinese Health Food

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