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  • Open Access


    Transcatheter Closure vs. Surgical Ligation in Preterm Infants with Patent Ductus Arteriosus: A Systematic Review and Meta-Analysis

    Rohan Suresh Daniel1,2, Georgia K. Schmidt1,2, Hayato Nakanishi1,2, Karen Smayra1,2, Mariah N. Mascara1,2, Dilip K. Vankayalapati1,2, Reem H. Matar1,2,3, Christian A. Than1,2,4, George Shiakos5, Ioannis Tzanavaros2,5,*

    Congenital Heart Disease, Vol.18, No.2, pp. 245-265, 2023, DOI:10.32604/chd.2023.027596

    Abstract Background: Persistent patent ductus arteriosus (pPDA) is a common condition in preterm infants. This meta-analysis aimed to assess the safety and efficacy of transcatheter closure (TC) when compared to surgical ligation (SL) in preterm infants with pPDA. Methods: A literature search of Ovid Cochrane Library, Medline, Embase, Epub, Scopus, PMC Preprints, and was conducted from inception to May 06, 2022. Eligible studies reported infants diagnosed with pPDA born at ≤2000 g birth weight or at ≤37 weeks’ who underwent TC or SL as treatment. This review was registered in PROSPERO (CRD42022325944). Results: From 97 studies screened, 8 studies met the… More >

  • Open Access


    The Prevalence of Congenital Heart Disease among School-Age Children in China: A Meta-Analysis and Systematic Review

    Shuqin Zhang1,#, Bin Zhang2,#, Jianying Wu3, Jin Luo1, Haomin Shi1, Jirong Qi3,4,*, Huilian Yang1,5,*

    Congenital Heart Disease, Vol.18, No.2, pp. 127-150, 2023, DOI:10.32604/chd.2023.025616

    Abstract Objectives: To estimate the prevalence of Congenital Heart Disease (CHD) in school-age children, to identify the extent to which altitude affects the prevalence of the disease, and to examine trends in prevalence over time in China. Methods: Seven databases were systematically searched and last retrieved on September 10, 2021 for all studies reporting the prevalence of CHD in children after 1970 in China, which were then divided into high and low altitude regions based on 2500 meters above sea level. The random-effected model was used to combine prevalence data and subgroups analysis. The baseline data of all cases and individuals… More > Graphic Abstract

    The Prevalence of Congenital Heart Disease among School-Age Children in China: A Meta-Analysis and Systematic Review

  • Open Access


    Effects of Internet-Based Acceptance and Commitment Therapy (IACT) on Adolescents: A Systematic Review and Meta-Analysis

    Jing Wang, Shuanghu Fang*

    International Journal of Mental Health Promotion, Vol.25, No.4, pp. 433-448, 2023, DOI:10.32604/ijmhp.2023.025304

    Abstract Objectives: This study reviewed published randomized controlled trials (RCTs) and evaluated the efficacy of internet-based acceptance and commitment therapy (IACT) on adolescent mental health. Methods: Searches were conducted in PubMed, ProQuest, APA (PsycNET/PsycINFO), and Web of Science from inception to January 2022 to identify RCTs evaluating the effects of IACT on adolescents. The included studies were assessed for quality and risk of bias. This study was performed using the standard mean difference and associated 95% confidence interval of effective measures. Review Manager 5.4 software was adopted to calculate the effect size. Results: Compared to adolescents in control groups, those in… More >

  • Open Access


    Effects of Big Five, HEXACO, and Dark Triad on Counterproductive Work Behaviors: A Meta-Analysis

    Yating Miao1,2,*, Jigan Wang1, Rundian Shen1, Dongsheng Wang3

    International Journal of Mental Health Promotion, Vol.25, No.3, pp. 357-374, 2023, DOI:10.32604/ijmhp.2023.027950

    Abstract Purpose: This study investigates the effects of Big Five, HEXACO, and Dark Triad personality traits on counterproductive work behaviors (CWBs), and examines the moderating effects of countries where the studies were carried out, gender rate of samples, and scales used to measure personalities. Method: Following the rules of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), we include 74 empirical studies published between 2007 and September 2022 with 83 samples and 394 correlations. Studies are selected from both English databases such as Web of Science and Chinese databases such as CNKI. The meta-analysis and metaregression analysis were both performed… More >

  • Open Access


    Research on Clinical Effectiveness of Aspirin for Treating Breast Cancer and Cell Protein Biomarkers on Aspirin Treatment in Drug-Resistant Estrogen Receptor-Positive Breast Cancer Cells

    Junwei Cui1, Minghua Li2, Ruifang Pang2,*, Yinhua Liu1,*

    Oncologie, Vol.24, No.4, pp. 743-768, 2022, DOI:10.32604/oncologie.2022.025419

    Abstract Background: Aspirin (ASA) has been reported to have an antitumor effect but the role of ASA in the prevention and treatment of breast cancer (BC) is still controversial. This study aimed to identify clinical effectiveness of ASA in the treatment of BC and explore the antitumor target proteins of ASA that may be involved in overcoming tamoxifen resistance in estrogen receptor (ER)-positive BC cells. Materials and Methods: Randomized controlled trials (RCTs) of ASA in the treatment of BC were queried from the databases, including PubMed, Web of Science, Cochrane Library, WanFang, and Chinese National Knowledge Infrastructure. According to the quality… More >

  • Open Access


    Validation of Symptom Dimensions and Sub-Type Responses in Cognitive Behavioral Therapy in Obsessive Compulsive Disorder: A Systemic Review and Meta-Analysis

    Xuan Liu1,2,3, Xiangyun Yang1,2, Pengchong Wang1,2, Zhanjiang Li1,2,*

    International Journal of Mental Health Promotion, Vol.24, No.6, pp. 843-854, 2022, DOI:10.32604/ijmhp.2022.021009

    Abstract Background: Obsessive-compulsive disorder (OCD) is a clinically heterogeneous condition without a conclusive subtype dimension. This study will focus on the meta-analysis of the clinical responses of OCD subtypes to cognitive behavioral therapy (CBT), which might clarify this issue. Methods: We performed a systematic search and a meta-analysis for the studies of OCD subtypes and the response to CBT in PubMed, ScienceDirect, Embase, Web of Science, and Scopus databases. The selective criteria were the OCD without significant medical or psychiatric co-morbidities and pre-and post-treatment changes in scores of OCD dimension. In addition, different subtypes of OCD in symptom dimensions, such as… More >

  • Open Access


    The Relationship between T-Wave Alternans and Adverse Cardiac Events in Patients with Congenital Long QT Syndrome: A Systematic Review and Meta-Analysis

    Ying Yang1,#, Tingting Lv2,#, Siyuan Li1, Ping Zhang1,2,*

    Congenital Heart Disease, Vol.17, No.5, pp. 557-567, 2022, DOI:10.32604/CHD.2021.017292

    Abstract Background: T-wave alternans (TWA) is a risk factor of ventricular arrhythmias or sudden cardiac death (SCD) in patients with ischemic cardiomyopathy. Nevertheless, the relationship between TWA and adverse cardiac events (ACE) in patients with congenital long QT syndrome (LQT) remains controversial. Methods: A systematic electronic search of PubMed, Embase and the Cochrane Library was conducted from database inception dates to 28 April 2021 and assessed the relationship between TWA and ACE in patients with LQTS. Sub-group analysis evaluated the association between microvolt TWA (MTWA) and ACE in different monitoring models and ECGlead numbers. Results: A pooled analysis of seven studies… More >

  • Open Access


    Efficacy of oral consumption of curcumin/ for symptom improvement in inflammatory bowel disease: A systematic review of animal models and a meta-analysis of randomized clinical trials


    BIOCELL, Vol.46, No.9, pp. 2015-2047, 2022, DOI:10.32604/biocell.2022.020407


    The roots of the vegetal Curcuma due to its high content of polyphenols, has been used successfully in several clinical situations. This review assessed the effect of curcumin/Curcuma longa on symptoms and metabolic changes in inflammatory bowel disease (IBD). A systematic review of animal models and randomized clinical trials (RCTs) was conducted by searching the following electronic databases: PubMed, CENTRAL, LILACS, Science Direct, and ClinicalTrials.gov. From 997 found records, 62 were included. More than 90% of the animal studies reported an improvement in macroscopic, histologic and/or functional activity; 80% identified decreased oxidative and/or inflammatory biomarkers in animals treated with curcumin.… More >

  • Open Access


    Meta-Analysis of Flowering-Related Traits and Mining of Candidate Genes in Maize

    Jianyu Lu1, Qingping Jiang1, Tongyu Liu1, Yangyang Zhou1, Mengtong Liu1, Jing Qu2, Yiyong Ma2,*, Shuyan Guan2,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.6, pp. 1199-1209, 2022, DOI:10.32604/phyton.2022.019298

    Abstract Maize flowering is an important agronomic character, which is controlled by quantitative trait loci (QTL). Over the years, a large number of flowering-related QTL have been found in maize and exist in public databases. However, combining these data, re-analyzing and mining candidate loci and fine mapping of flowering-related traits to reduce confidence intervals has become a hot issue in maize. In this study, the QTL of 6 important agronomic traits of maize flowering were collected from 15 published articles, including flowering period (DA), Days to tasseling (DTT), Days to silking (DS), Days to pollen shedding (DTP), anthesis-silking interval (ASI) and… More >

  • Open Access


    Prevalence of Bicuspid Aortic Valve in Turner Syndrome Patients Receiving Cardiac MRI and CT: A Meta-Analysis

    Pengzhu Li, Martina Bačová, Robert Dalla-Pozza, Nikolaus Alexander Haas, Felix Sebastian Oberhoffer*

    Congenital Heart Disease, Vol.17, No.2, pp. 129-141, 2022, DOI:10.32604/CHD.2022.018300

    Abstract Turner syndrome (TS) is a rare disorder affecting 25–50 in 100000 female newborns. Bicuspid aortic valve (BAV) is assumed to be the most common congenital heart defect (CHD) in TS. In literature, reported BAV prevalence in TS ranges between 14% and 34%. The specific BAV prevalence in TS is still unknown. The aim of this study was to give a more precise estimation of BAV prevalence in TS by conducting a meta-analysis of TS-studies, which detected BAV by either cardiac magnetic resonance imaging (MRI) or cardiac computed tomography (CT). We searched PubMed, Cochrane Library, and Web of Science databases to… More >

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