Wei Tian¹, Lingdi Liu¹, Zhongxing Song², Zhishu Tang², Chunxiu Wen¹, Tao Jiang^1,*

Phyton-International Journal of Experimental Botany, Vol.92, No.2, pp. 369-382, 2023, DOI:10.32604/phyton.2022.023184

Abstract The extract from Semen Ziziphi Spinosae (SZS) contains many secondary metabolites (flavonoids, alkaloids, and terpenoids), widely reported for their high medicinal value. In order to know the number and type of flavonoids and the regulating mechanism of flavonoid biosynthesis during the growth and development of SZS, we identified and analyzed the flavonoid metabolites and genes in SZS using metabolomic and transcriptomic. A total of 13,232 differentially expressed genes and 83 flavonoid metabolites were identified at three different growth and development stages (T1, T2, and T3) of SZS. The main flavonoid metabolic components of SZS were catechin, L-epicatechin, (–)-epigallocatechin, (+)-gallocatechin, spinosin… More >

Yan Wan^1,#, Yuan Liang^1,#, Xuxiao Gong^1,#, Jianyong Ouyang¹, Jingwei Huang², Xiaoyong Wu¹, Qi Wu¹, Changying Liu¹, Xueling Ye¹, Xiaoning Cao³, Gang Zhao¹, Liang Zou^1,*, Dabing Xiang^1,*

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 35-54, 2023, DOI:10.32604/phyton.2022.021698

Abstract Tartary buckwheat (Fagopyrum tataricum) is an important pseudocereal feed crop with medicinal and nutritional value. Drought is one of the main causes of reduced growth and yield in these plants. We investigated the growth, physiological, and metabolic responses of the widely promoted Tartary buckwheat variety Chuan Qiao No. 1 to polyethylene glycol (PEG)-mediated drought stress. Drought significantly decreased shoot length, shoot biomass and relative water content. Root length, malondialdehyde content, electrolyte leakage, activities of superoxide dismutase, peroxidase, catalase and amylase, and contents of soluble sugar, soluble protein and proline were increased by PEG-mediated drought. Untargeted metabolomics analysis identified 32 core… More >

Xin Hu^1,2,#, Fangyu Jing^3,#, Qingjun Wang^1,4, Linyang Shi¹, Yunfeng Cao^4,5, Zhitu Zhu^1,4,*

Oncologie, Vol.23, No.2, pp. 203-217, 2021, DOI:10.32604/Oncologie.2021.016155

Abstract It is noteworthy that colon cancer is the fourth place in new cases and the fifth in mortalities according to global cancer statistics 2018. Tumorigenesis displays specific correlation with metabolic alterations. A variety of metabolites, including ornithine (Orn), are related to colon cancer according to sources of disease metabolic information retrieval in human metabolome database. The metabolic regulation of Orn pathway is a key link in the survival of cancer cells. In this study, the plasma Orn levels in colon cancer patients and healthy participants were measured by liquid chromatography tandem mass spectrometry, and the metabolic disturbances of Orn in… More >