J. Shanthini¹, P. Punitha^2,*, S. Karthik²

Computer Systems Science and Engineering, Vol.44, No.3, pp. 2619-2636, 2023, DOI:10.32604/csse.2023.027330

Abstract In today's Internet routing infrastructure, designers have addressed scaling concerns in routing constrained multiobjective optimization problems examining latency and mobility concerns as a secondary constrain. In tactical Mobile Ad-hoc Network (MANET), hubs can function based on the work plan in various social affairs and the internally connected hubs are almost having the related moving standards where the topology between one and the other are tightly coupled in steady support by considering the touchstone of hubs such as a self-sorted out, self-mending and self-administration. Clustering in the routing process is one of the key aspects to… More >

Dandan Wu^*1, Jun Liu^†1, Jianliang Chen^*, Haiyan He^*, Hang Ma^*, Xuedong Lv^*

Oncology Research, Vol.27, No.2, pp. 227-235, 2019, DOI:10.3727/096504018X15213089759999

Abstract MicroRNAs (miRNAs) have been reported to be involved in many human cancers and tumor progression. The dysregulation of miR-449a is found in many types of malignancies and is associated with tumor growth, migration, and invasion. However, its expression and function in non-small cell lung cancer (NSCLC) still remains unclear. In our study, miR-449a was found to be downregulated in both NSCLC tissues and cell lines, and low miR-449a expression was obviously associated with tumor differentiation, TMN stage, and poor overall survival (OS). Moreover, we demonstrated that miR-449a could inhibit tumor proliferation, migration, and invasion in More >

Yosuke Mitsui^*†, Nahoko Tomonobu^*, Masami Watanabe^†, Rie Kinoshita^*, I Wayan Sumardika^*‡, Chen Youyi^*, Hitoshi Murata^*, Ken-ichi Yamamoto^*, Takuya Sadahira^†, Acosta Gonzalez Herik Rodrigo^*†, Hitoshi Takamatsu^*, Kota Araki^*§, Akira Yamauchi^¶, Masahiro Yamamura^#, Hideyo Fujiwara^**, Yusuke Inoue^††, Junichiro Futami^‡‡, Ken Saito^§§, Hidekazu Iioka^§§, Eisaku Kondo^§§, Masahiro Nishibori^¶¶, Shinichi Toyooka^§, Yasuhiko Yamamoto^##, Yasutomo Nasu^†, Masakiyo Sakaguchi^*

Oncology Research, Vol.27, No.8, pp. 945-956, 2019, DOI:10.3727/096504019X15555408784978

Abstract S100A11, a member of the S100 family of proteins, is actively secreted from pancreatic ductal adenocarcinoma (PDAC) cells. However, the role of the extracellular S100A11 in PDAC progression remains unclear. In the present study, we investigated the extracellular role of S100A11 in crosstalking between PDAC cells and surrounding fibroblasts in PDAC progression. An abundant S100A11 secreted from pancreatic cancer cells stimulated neighboring fibroblasts through receptor for advanced glycation end products (RAGE) upon S100A11 binding and was followed by not only an enhanced cancer cell motility in vitro but also an increased number of the PDAC-derived… More >

Chenglin Qin^*†, Linfang Jin^*‡, Jia Li^*§, Wenzhang Zha^†, Huiming Ding^†, Xiaorong Liu^*¶, Xun Zhu^*

Oncology Research, Vol.28, No.5, pp. 483-495, 2020, DOI:10.3727/096504020X15928179818438

Abstract Long intergenic nonprotein-coding RNA 02163 (LINC02163) has been reported to be upregulated and work as an oncogene in gastric cancer. The aims of the present study were to determine the expression profile and clinical value of LINC02163 in breast cancer. Additionally, the detailed functions of LINC02163 in breast cancer were explored, and relevant molecular events were elucidated. In this study, LINC02163 was upregulated in breast cancer, and its expression level was closely associated with tumor size, lymph node metastasis, and TNM stage. Patients with breast cancer presenting high LINC02163 expression exhibited shorter overall survival than… More >

R. Meenakshi¹, R. Ponnusamy^1,*, Saleh Alghamdi², Osama Ibrahim Khalaf³, Youseef Alotaibi⁴

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 3473-3495, 2022, DOI:10.32604/cmc.2022.028540

Abstract In 2017, it was estimated that the number of persons of all ages visually affected would be two hundred and eighty-five million, of which thirty-nine million are blind. There are several innovative technical solutions available to facilitate the movement of these people. The next big challenge for technical people is to give cost-effective solutions. One of the challenges for people with visual impairments is navigating safely, recognizing obstacles, and moving freely between locations in unfamiliar environments. A new mobile application solution is developed, and the application can be installed in android mobile. The application will More >

Lixia Niu^1,*, Ying Liu¹, Jie Liu², Rui Zhao¹

International Journal of Mental Health Promotion, Vol.24, No.4, pp. 527-538, 2022, DOI:10.32604/ijmhp.2022.017484

Abstract To clarify the mechanism of blocking-stressors, psychological contracts, and negative emotions on post-90s employees’ occupational mobility, based on the literature study, a hypothetical model of the relationship was established. Using the blocking-stressor, psychological contract, negative emotion, and occupational mobility scales, 317 post-90s employees were selected to investigate their status. It used correlation analysis and intermediary effect tests to verify the hypothesis model. The results showed that: first, there were significant positive correlations between blocking-stressors, negative emotions, and occupational mobility, while indicating a significant negative correlation with the psychological contract; second, blocking-stressors can directly and significantly More >

B. Gomathi¹, S. T. Suganthi^2,*, T. N. Prabhu³, Andriy Kovalenko⁴

Intelligent Automation & Soft Computing, Vol.34, No.3, pp. 1851-1860, 2022, DOI:10.32604/iasc.2022.026779

Abstract On the Internet of Vehicle (IoV) devices, offloading data is the major problem because massive amounts of data generate energy consumption, and the execution cost is high. At present, accidents traffic management is highly prominent due to increased vehicles among the population. IoV is the only technology to help the transport system effectively. This data outreach the memory also has high energy consumption, and the storage cost is high. To overcome these issues, a Mobility aware Offloading scheme with Multi-Objective Immune Optimization algorithm (MOS-MOIO) is used in the cloud storage. The data is generated from More >

Abdulraqeb Alhammadi^1,*, Wan Haslina Hassan¹, Ayman A. El-Saleh², Ibraheem Shayea³, Hafizal Mohamad⁴, Yousef Ibrahim Daradkeh⁵

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5215-5232, 2022, DOI:10.32604/cmc.2022.024713

Abstract Fifth-generation (5G) cellular networks offer high transmission rates in dense urban environments. However, a massive deployment of small cells will be required to provide wide-area coverage, which leads to an increase in the number of handovers (HOs). Mobility management is an important issue that requires considerable attention in heterogeneous networks, where 5G ultra-dense small cells coexist with current fourth-generation (4G) networks. Although mobility robustness optimization (MRO) and load balancing optimization (LBO) functions have been introduced in the 3GPP standard to address HO problems, non-robust and nonoptimal algorithms for selecting appropriate HO control parameters (HCPs) still… More >

D. Kothandaraman^1,*, M. Manickam², A. Balasundaram³, D. Pradeep⁴, A. Arulmurugan⁵, Arun Kumar Sivaraman⁶, Sita Rani⁷, Barnali Dey⁸, R. Balakrishna⁹

Intelligent Automation & Soft Computing, Vol.34, No.1, pp. 655-666, 2022, DOI:10.32604/iasc.2022.024134

Abstract This work implements a Decentralized Links Failure Prevention (DLFP) routing algorithm to promote enhanced and efficient Internet of Things (IoT). The work increases the mobility as well as an opportunity for loss of IoT node meeting links due to both mobility and blockers/interferers. The proposed algorithm overcomes loss issues as well as works in dynamically allocating alternate route from other IoT nodes available in near and selecting for efficient route in the network. When the link fails, bandwidth is reduced and coverage area problems for packets sending from source to destination is managed. The proposed… More >

M. Almutiq¹, L. Sellami^1,2,*, B. Alaya^1,3

CMC-Computers, Materials & Continua, Vol.72, No.2, pp. 3493-3510, 2022, DOI:10.32604/cmc.2022.024571

Abstract Nowadays, video streaming applications are becoming one of the tendencies driving vehicular network users. In this work, considering the unpredictable vehicle density, the unexpected acceleration or deceleration of the different vehicles included in the vehicular traffic load, and the limited radio range of the employed communication scheme, we introduce the “Dynamic Vehicular Clustering” (DVC) algorithm as a new scheme for video streaming systems over vehicular ad-hoc networks (VANET). The proposed algorithm takes advantage of the small cells concept and the introduction of wireless backhauls, inspired by the different features and the performance of the Long… More >