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Search Results (3)
  • Open Access


    Multimodal Imaging with 3D-Holograms for Preoperative Planning in Pediatric Cardiac Surgery: A Unique Case Report

    Federica Caldaroni1, Massimo Chessa2, Alessandro Varrica1, Alessandro Giamberti1,*

    Congenital Heart Disease, Vol.17, No.4, pp. 491-494, 2022, DOI:10.32604/chd.2022.019119

    Abstract Multimodal imaging, including augmented or mixed reality, transforms the physicians’ interaction with clinical imaging, allowing more accurate data interpretation, better spatial resolution, and depth perception of the patient’s anatomy. We successfully overlay 3D holographic visualization to magnetic resonance imaging images for preoperative decision making of a complex case of cardiac tumour in a 7-year-old girl. More >

  • Open Access


    Brain Tumor Auto-Segmentation on Multimodal Imaging Modalities Using Deep Neural Network

    Elias Hossain1, Md. Shazzad Hossain2, Md. Selim Hossain3, Sabila Al Jannat4, Moontahina Huda5, Sameer Alsharif6, Osama S. Faragallah7, Mahmoud M. A. Eid8, Ahmed Nabih Zaki Rashed9,*

    CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 4509-4523, 2022, DOI:10.32604/cmc.2022.025977

    Abstract Due to the difficulties of brain tumor segmentation, this paper proposes a strategy for extracting brain tumors from three-dimensional Magnetic Resonance Image (MRI) and Computed Tomography (CT) scans utilizing 3D U-Net Design and ResNet50, taken after by conventional classification strategies. In this inquire, the ResNet50 picked up accuracy with 98.96%, and the 3D U-Net scored 97.99% among the different methods of deep learning. It is to be mentioned that traditional Convolutional Neural Network (CNN) gives 97.90% accuracy on top of the 3D MRI. In expansion, the image fusion approach combines the multimodal images and makes a fused… More >

  • Open Access


    IR780 loaded hollow MnO2 nanoparticles for dual-mode imaging and enhanced photodynamic therapy of oral squamous cell carcinoma

    WEI PAN1,2,3,*, YE HE1, MENGDONG HE1,2,3, FEI WANG1,2,3, LIHUA QIU1,2

    BIOCELL, Vol.46, No.4, pp. 1079-1088, 2022, DOI:10.32604/biocell.2022.016934

    Abstract Photodynamic therapy (PDT) has emerged as a novel therapeutic modality for cancer treatment, but its therapeutic efficacy is severely limited by the hypoxic tumor microenvironment (TME). Here we designed an innovative multifunctional nano-platform which consists of a hollow MnO2 shell and internal photosensitizer IR780. It is not only used for multimodal imaging of oral squamous cell carcinoma (OSCC), but also for adjustment hypoxic TME to enhance cancer treatment. Hollow MnO2 can promote decomposition of tumor endogenous H2O2 to relieve tumor hypoxia, thereby enhancing the effect of photodynamic therapy. Photosensitizer IR780 generates singlet oxygen under laser irradiation to More >

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