Katharina Niedermayr¹, Gerhard Pölzl², Sabine Scholl‐Bürgi¹, Christine Fauth³, Ulrich Schweigmann¹, Edda Haberlandt¹, Ursula Albrecht¹, Manuela Zlamy¹, Wolfgang Sperl⁴, Johannes A. Mayr⁴, Daniela Karall¹

Congenital Heart Disease, Vol.13, No.5, pp. 671-677, 2018, DOI:10.1111/chd.12634

Abstract Objective: In general, a mitochondrial disorder is diagnosed on the basis of symptom combinations and confirmed by genetic findings. However, patients carrying the m.3243A>G mutation in the mitochondrial tRNA leucine 1 (MT‐TL1) do not always meet all the proposed criteria for the most frequently encountered mitochondrial syndrome “MELAS,” an acronym for Mitochondrial Encephalomyopathy, Lactic Acidosis, and at least one Stroke‐like episode. We here present various phenotypic characteristics of the mitochondrial mutation m.3243A>G with particular focus on cardiac manifestations.
Methods and Results: We followed nine patients (1 month to 68 years old; median 42 years; four female and five male) from… More >

Fariborz Soheili^1,2, Zahra Jalili³, Mahtab Rahbar⁴, Zahed Khatooni¹, Amir Mashayekhi⁵, Hossein Jafari⁶

Congenital Heart Disease, Vol.13, No.2, pp. 295-304, 2018, DOI:10.1111/chd.12571

Abstract Background: The mutations in GATA4 gene induce inherited atrial and ventricular septation defects, which is the most frequent forms of congenital heart defects (CHDs) constituting about half of all cases.
Method: We have performed High resolution melting (HRM) mutation scanning of GATA4 coding exons of nonsyndrome 100 patients as a case group including 39 atrial septal defects (ASD), 57 ventricular septal defects (VSD) and four patients with both above defects and 50 healthy individuals as a control group. Our samples are categorized according to their HRM graph. The genome sequencing has been done for 15 control samples and 25 samples… More >

Yao SUN, Yao LI, Xin SUN, Qiong WU, Lei WANG^*

BIOCELL, Vol.44, No.1, pp. 117-126, 2020, DOI:10.32604/biocell.2020.08242

Abstract Phosphorylation is a common type of post-translational modification (PTM). It plays a vital role in many cellular processes. The reversible phosphorylation and dephosphorylation affect protein structures and proteinprotein interactions. Previously, we obtained five proteins that interact with ethylene-responsive factor (ERF) from the cDNA library of Populus simonii x Populus nigra. To further investigate the effect of dephosphorylation of PsnERF on its protein binding ability, we generated different phosphorylation states of PsnERF and demonstrated their protein binding capacity by the yeast two-hybrid assay (Y2H). The secondary structures and 3D structures of PsnERF, ERFm, TrunERF, and psnerf^197/198/202a were predicted by homology modeling.… More >

Wenyan Guo^{1, *}, Ting Liu¹, Fang Dai¹, Peng Xu¹

CMC-Computers, Materials & Continua, Vol.62, No.1, pp. 337-354, 2020, DOI:10.32604/cmc.2020.06411

Abstract Whale optimization algorithm (WOA) is a new population-based metaheuristic algorithm. WOA uses shrinking encircling mechanism, spiral rise, and random learning strategies to update whale’s positions. WOA has merit in terms of simple calculation and high computational accuracy, but its convergence speed is slow and it is easy to fall into the local optimal solution. In order to overcome the shortcomings, this paper integrates adaptive neighborhood and hybrid mutation strategies into whale optimization algorithms, designs the average distance from itself to other whales as an adaptive neighborhood radius, and chooses to learn from the optimal solution in the neighborhood instead of… More >

NILTON CESAR PIRES BIONE¹, MARIA SUELY PAGLIARINI², LEONES ALVES DE ALMEIDA³

BIOCELL, Vol.29, No.2, pp. 177-181, 2005, DOI:10.32604/biocell.2005.29.177

Abstract A spontaneous male-sterile, female-fertile mutation affecting bivalent arrangement at the metaphase plate and cytokinesis was detected in line BR98-197 of the soybean breeding program developed by Embrapa – National Soybean Research Centre. Untill diakinesis, meiosis was normal with chromosome pairing as bivalents. From this phase, in several meiocytes, bivalents were not able to organize a single metaphase plate and remained scattered in the cytoplasm in a few or several groups. In these meiocytes, chromosomes segregated in both divisions giving rise to several micronuclei. However, the main cause of male sterility was the absence of cytokinesis after telophase II. Instead of… More >

López Colomba E¹, A Prina², S Griffa¹, AN Ribotta¹, E Carloni¹, E Tommasino¹, C Luna¹, E Biderbost¹, K Grunberg¹

Phyton-International Journal of Experimental Botany, Vol.80, pp. 59-64, 2011, DOI:10.32604/phyton.2011.80.059

Abstract Cenchrus ciliaris L., a forage grass of wide distribution in the north-west of Argentina, is a tetraploid (4x = 36) and obligate apomictic species. One way of obtaining novel germplasm is by induced mutations. In this work, physical and chemical mutations are combined with in vitro selection procedures seeking for new germplasm, with emphasis on salinity and drought tolerance. Mature seeds of Cenchrus ciliaris L. cv Biloela were subjected to treatments with X rays (400 Gy) and ethyl methanesulphonate (EMS) water solution (5.5 mM for 24 h). To perform in vitro selection, after 7 days of EMS or X rays… More >

Qun Mo¹, Heng Yao¹, Fang Cao², Zheng Chang³, Chuan Qin^1,*

CMC-Computers, Materials & Continua, Vol.59, No.1, pp. 119-133, 2019, DOI:10.32604/cmc.2019.05770

Abstract Recently, reversible data hiding in encrypted image (RDHEI) has attracted extensive attention, which can be used in secure cloud computing and privacy protection effectively. In this paper, a novel RDHEI scheme based on block classification and permutation is proposed. Content owner first divides original image into non-overlapping blocks and then set a threshold to classify these blocks into smooth and non-smooth blocks respectively. After block classification, content owner utilizes a specific encryption method, including stream cipher encryption and block permutation to protect image content securely. For the encrypted image, data hider embeds additional secret information in the most significant bits… More >

Nizami Gasilov¹, Şahin Emrah Amrahov², Afet Golayoğlu Fatullayev¹, Halil İbrahim Karakaş¹, Ömer Akın³

CMES-Computer Modeling in Engineering & Sciences, Vol.75, No.3&4, pp. 189-204, 2011, DOI:10.3970/cmes.2011.075.189

Abstract In this paper, linear systems with a crisp real coefficient matrix and with a vector of fuzzy triangular numbers on the right-hand side are studied. A new method, which is based on the geometric representations of linear transformations, is proposed to find solutions. The method uses the fact that a vector of fuzzy triangular numbers forms a rectangular prism in n-dimensional space and that the image of a parallelepiped is also a parallelepiped under a linear transformation. The suggested method clarifies why in general case different approaches do not generate solutions as fuzzy numbers. It is geometrically proved that if… More >