Javaid Ali¹, Shaukat Iqbal², Salem Alkhalaf^3,*

Intelligent Automation & Soft Computing, Vol.32, No.1, pp. 149-166, 2022, DOI:10.32604/iasc.2022.021788

Abstract This paper proposes a novel gradient free multi-simplex topology fabric aided imperialist competitive algorithm (ICA) for solving nonlinear systems of algebraic equations by transforming them to equivalent global optimization problems. The high dependence of traditional gradient based solvers of such systems on initial guesses and the Jacobeans resulting in false convergence is the main motivation behind the present work. The present work provides a mechanism for enhancing exploitation powers of imperialist search phase of the algorithm and hence improves the convergence speed. The variants emerging from the proposed approach are applied to diverse nonlinear systems arising in different scientific areas… More >

Yanju Wei^1,*, Shengcai Deng¹, Jie Zhang¹, Yajing Yang², Hao Chen³

Energy Engineering, Vol.118, No.2, pp. 225-235, 2021, DOI:10.32604/EE.2021.012416

Abstract The aerodynamic breakup of the droplet has been intensely studied in this paper. We aim to establish a unified relationship between dimensionless kinematic parameters such as displacement, spreading diameter, Weber number, time, and so on. The breakup characteristics of the acoustic levitated ethanol droplet are experimentally investigated when exposed to an air jet flow. The breakup phenomenons were recorded with a high-speed camera. The breakup characteristics were analyzed, and the physical models of the moving and transforming behaviors were established to explain the breakup mechanisms. We found that the displacement of the windward side of the droplet follows free acceleration… More >

Zhiyong Li^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 29-30, 2019, DOI:10.32604/mcb.2019.06308

Abstract In this article, we summarize our previous work in imaging-based computational modelling and simulation of the interaction between blood flow and atherosclerotic plaque. We also discussed our recent developments in multiphysical modelling of plaque progression and destabilization. Significance and translation of the modelling study to clinical practice are discussed in order to better assess plaque vulnerability and accurately predict a possible rupture. More >

Linggang Kong, Yunmin Chen, Yanguo Zhou, Jianqun Jiang

The International Conference on Computational & Experimental Engineering and Sciences, Vol.20, No.4, pp. 107-108, 2011, DOI:10.3970/icces.2011.020.107

Abstract To investigate geotechnical systems, high gravity is needed due to the dominance of material self-weight. A centrifuge is a common technique to generate high gravity, which causes centrifugal acceleration. In geotechnical physical modeling, geotechnical centrifuge can generate the same gravity stress as the prototype, guarantees the consistency of model deformation and failure mechanism between the centrifugal model and real objects and solve complex problems in geotechnical engineering, hydraulic engineering and environmental engineering etc. In view of the scientific values of centrifuge and shaking table, Zhejiang University develops one of the largest geotechnical centrifuges in China. The centrifuge is a beam… More >

Yunfeng Chen^1,2,3,†,*, Jiexi Liao^4,†, Zhou Yuan¹, Kaitao Li⁴, Baoyu Liu⁴, Lining Arnold Ju^4,5,6, Cheng Zhu^1,2,4,*

Molecular & Cellular Biomechanics, Vol.16, No.3, pp. 211-223, 2019, DOI:10.32604/mcb.2019.07267

Abstract Force plays critical roles in cell adhesion and mechano-signaling, partially by regulating the dissociation rate, i.e., off-rate, of receptor-ligand bonds. However, the mechanism of such regulation still remains elusive. As a controversial topic of the field, when measuring the “off-rate vs. force” relation of the same molecular system, different dynamic force spectroscopy (DFS) assays (namely, force-clamp and force-ramp assays) often yield contradictive results. Such discrepancies hurdled our further understanding of molecular binding, and casted doubt on the existing theoretical models. In this work, we used a live-cell DFS technique, biomembrane force probe, to measure the single-bond dissociation in three receptor-ligand… More >

Cheng Zhu¹, Rodger P. McEver²

Molecular & Cellular Biomechanics, Vol.2, No.3, pp. 91-104, 2005, DOI:10.3970/mcb.2005.002.091

Abstract Force can shorten the lifetimes of receptor-ligand bonds by accelerating their dissociation. Perhaps paradoxical at first glance, bond lifetimes can also be prolonged by force. This counterintuitive behavior was named catch bonds, which is in contrast to the ordinary slip bonds that describe the intuitive behavior of lifetimes being shortened by force. Fifteen years after their theoretical proposal, catch bonds have finally been observed. In this article we review recently published data that have demonstrated catch bonds in the selectin system and suggested catch bonds in other systems, the theoretical models for their explanations, and their function as a mechanism… More >

Patrícia C.T. Gonçalves^1,2, João Manuel R.S. Tavares^1,2, R.M. Natal Jorge^1,3

CMES-Computer Modeling in Engineering & Sciences, Vol.32, No.1, pp. 45-56, 2008, DOI:10.3970/cmes.2008.032.045

Abstract The main goals of the present work are to automatically extract the contour of an object and to simulate its deformation using a physical approach. In this work, to segment an object represented in an image, an initial contour is manually defined for it that will then automatically evolve until it reaches the border of the desired object. In this approach, the contour is modelled by a physical formulation using the finite element method, and its temporal evolution to the desired final contour is driven by internal and external forces. The internal forces are defined by the intrinsic characteristics of… More >

H. Chanson¹, K.K. Tan²

FDMP-Fluid Dynamics & Materials Processing, Vol.7, No.4, pp. 403-418, 2011, DOI:10.3970/fdmp.2011.007.403

Abstract A tidal bore is a wall of water propagating upstream as the tidal flow turns to rising into an estuary with a tidal range larger than 5 to 6 m and the bathymetry that amplifies the tidal wave. The bore front is a shock characterised by a singularity of the free-surface and pressure and velocity fields. This study aims to characterise the impact of tidal bores on the turbulent dispersion of fish eggs. Some physical modelling was performed based upon a Froude similitude and the tracking of plastic beads acting as fish egg proxies was conducted under controlled flow conditions… More >