Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (8)
  • Open Access

    REVIEW

    Curcumin in inflammatory bowel diseases: Cellular targets and molecular mechanisms

    AMYLLY SANUELLY DA PAZ MARTINS1,#, MARLA DE CERQUEIRA ALVES2,#, ORLANDO ROBERTO PIMENTEL DE ARAÚJO3, FABIANA OLIVEIRA DOS SANTOS CAMATARI4, MARÍLIA OLIVEIRA FONSECA GOULART1,3,5, FABIANA ANDRÉA MOURA2,6,*

    BIOCELL, Vol.47, No.11, pp. 2547-2566, 2023, DOI:10.32604/biocell.2023.043253

    Abstract

    Curcumin, a natural product, has exhibited promising effects in both animal models and clinical trials, interacting with a multitude of factors linked to Inflammatory Bowel Disease (IBD). These factors encompass cytokines, oxidative stress-associated enzymes, and modulation of the intestinal microbiota. Notably, curcumin has demonstrated therapeutic potential in animal models of colitis, wherein it exerts a negative regulatory influence on pivotal signaling pathways such as PI3/Akt, JAK/STAT, and β-catenin. Moreover, it inhibits the expression of pro-inflammatory enzymes and co-stimulatory molecules (including RANKL, ICAM-1, CD205, CD256, TLR4, among others), while curbing immune cell chemotaxis, thereby attenuating the characteristic neutrophil infiltration observed in… More > Graphic Abstract

    Curcumin in inflammatory bowel diseases: Cellular targets and molecular mechanisms

  • Open Access

    ARTICLE

    Thermally Stable Polymers of Cardanol as Char-Forming Additives for Polypropylene

    Weeradech Kiratitanavit1, Sethumadhavan Ravichandran2,Zhiyu Xia1, Jayant Kumar3,4, Ramaswamy Nagarajan1,4,*

    Journal of Renewable Materials, Vol.1, No.4, pp. 289-301, 2013, DOI:10.7569/JRM.2013.634126

    Abstract Globally, certain types of halogenated fl ame retardant additives (FR) are becoming increasingly regulated or banned from being used in polymers. There is an immediate need for alternative non-toxic thermally stable polymers and char-forming additives. Development of non-halogenated FR for the commonly used and highly fl ammable thermoplastics, namely polyolefi ns, is particularly important and challenging. This research explores the possibility of utilizing char-forming compounds based on polymer of cardanol as an additive that can lower the heat release capacity (HRC) when blended with polypropylene (PP). Polycardanol is thermally stable and exhibits moderate HRC upon thermal decomposition and forms a… More >

  • Open Access

    REVIEW

    Recent Technologies for the Extraction and Separation of Polyphenols in Different Plants: A Review

    Yingying Hu1,#, Bowen Yan1,#, Zhefan Stephen Chen2, Lei Wang3, Wei Tang1 and Caoxing Huang1,*

    Journal of Renewable Materials, Vol.10, No.6, pp. 1471-1490, 2022, DOI:10.32604/jrm.2022.018811

    Abstract Polyphenol is an important secondary metabolite with unique physiological functions and biological activity. The polyphenols in different plants and biomass have different chemical structures, which needs various extraction methods to obtain them. Recently, plant polyphenols and their application research in food and medicine have become a research hotspot, which is mainly focused on preparation, purification, structural identification, and biological activity assays. Among these researches, extraction and separation are the key sections to investigate the structure and activity of polyphenol. Hence, this review summarized the recent extraction and separation techniques of polyphenol, including solvent extraction, supercritical fluid extraction, ultrasonic extraction, enzymatic… More > Graphic Abstract

    Recent Technologies for the Extraction and Separation of Polyphenols in Different Plants: A Review

  • Open Access

    ARTICLE

    Ameliorative Role of Pre-Sowing Proline Treatment in Coriandrum sativum L. Seedlings under Mercury Toxicity

    Dhriti Kapoor1, Kapani Kavani1, Amandeep Rattan2, Marco Landi3,*, Anket Sharma4,*

    Phyton-International Journal of Experimental Botany, Vol.90, No.2, pp. 489-501, 2021, DOI:10.32604/phyton.2021.012359

    Abstract Heavy metal toxicity is one of the major ecosystem concerns globally in present time and is also responsible for significant threat to agronomic crops. The current work was conducted to investigate the possible ameliorative role of proline in Coriandrum sativum L. seedlings treated with mercury (Hg). The seedlings were exposed to different concentrations of Hg (0, 0.1, 0.3 and 0.5 mM) for 20 days. The effects of pre-sowing treatment with proline were studied on C. sativum seedlings in terms of pigment (chlorophylls, carotenoids and anthocyanins), malondialdehyde (MDA), antioxidant compound (glutathione, total phenolic compounds, ascorbic acid) and osmolytes (proline, glycine betaine).… More >

  • Open Access

    ARTICLE

    Polyphenolic profile of Origanum vulgare L. ssp. viridulum from Argentina

    González MD, CM Luis, PL Lanzelotti

    Phyton-International Journal of Experimental Botany, Vol.83, pp. 179-184, 2014, DOI:10.32604/phyton.2014.83.179

    Abstract Characterization of oregano in Argentina is limited. They are normally known with fancy names, but it is not possible to recognize whether they are genetically equivalent or not. This paper presents a non-volatile polyphenol study of one of the subspecies of Origanum vulgare, O. vulgare L. ssp. viridulum (Martrin-Donos) Nyman [= O. vulgare L. ssp. virens (Hoffmannsegg et Link) Ietswart]. The polyphenols 3-(3,4-dihydroxyphenyl)lactic acid, 3,4-dihydroxybenzoic acid, caffeic acid, 4-(3.4-dihydroxybenzoyloxymethyl)phenyl β-glucoside and rosmarinic acid were isolated and identified by spectroscopic analysis from leaves and inflorescences of classified material. In addition, the polyphenol profile of the hydroalcoholic extract of this oregano was… More >

  • Open Access

    ARTICLE

    Gene expression profiling of HepG2 cells after treatment with black tea polyphenols

    Jie Zhong1,#, Li Deng2,#, Yu Jiang3, Lianhong Zou3, Huabing Yuan4, Shuang-xiang Tan1,*

    BIOCELL, Vol.42, No.3, pp. 99-104, 2018, DOI:10.32604/biocell.2018.04915

    Abstract This study aimed to determine the effects of black tea polyphenols on gene expression in hepatocellular cancer cells. The total RNA from HepG2 hepatocellular cancer cells treated with black tea polyphenols was subjected to Human 14K cDNA microarray analysis. Real-time PCR and Western blot analysis were conducted to verify microarray data. Black tea polyphenols treatment at the dose of 20 mg/L, 40 mg/L or 80 mg/L for one to three days inhibited the growth of HepG2 cells in a dose and time dependent manner. A total of 48 genes showed more than two-fold change after black tea polyphenols treatment, including… More >

  • Open Access

    REVIEW

    Active compounds of medicinal plants, mechanism for antioxidant and beneficial effects

    Orozco Montes F1, A Vázquez-Hernández2, B Fenton-Navarro1

    Phyton-International Journal of Experimental Botany, Vol.88, No.1, pp. 1-10, 2019, DOI:10.32604/phyton.2019.04525

    Abstract An increased interest in the antioxidant effects of medicinal plants has developed in recent years. Identifying antioxidant compounds present in medicinal plants and elucidating the mechanism by which they prevent oxidation have been the focus of the research community. We performed a systematic and exhaustive review aimed at analyzing the available data regarding the beneficial effects of secondary metabolites in plants. The result of this review is presented as a description of free radicals, as well as cellular and physiological oxidative stress, is provided. The origin and source of antioxidant compounds, and the cellular and molecular mechanism by which they… More >

  • Open Access

    ARTICLE

    Extraction and Characterization of Aucoumea klaineana Pierre (Okoume) Extractives

    Engozogho Anris Starlin Peguy1,2, Bikoro Bi Athomo Arsene1,2, Vidal Marcia5, Denaud Louis4, Safou Tchiama Rodrigue2,3, Charrier Bertrand1

    Journal of Renewable Materials, Vol.7, No.6, pp. 517-522, 2019, DOI:10.32604/jrm.2019.04051

    Abstract In order to promote convenient strategies for the utilization of wood wastes from aucoumea klaineana pierre (okoume) timber industry, various chemical analysis were carried out on samples from different origins. Total extractives content of the bark, sapwood and heartwood of okoume were evaluated. thermogravimetric analyses were performed and the stiasny number was calculated. it was found that the bark was richer in fatty acid of high molecular weight while the sapwood was rich in fatty acid of low molecular weight. the condensed tannins content varied according to the origin and the part of the tree. these new findings should be… More >

Displaying 1-10 on page 1 of 8. Per Page