EUN NA¹, MYOUNGWON CHOI², INDAL PARK², SUNYOUNG LIM^3,*

BIOCELL, Vol.44, No.2, pp. 193-199, 2020, DOI:10.32604/biocell.2020.08648

Abstract We investigated the effect of black sea bream extracts on changes in pro-inflammatory and anti-inflammatory cytokines induced by lipopolysaccharide (LPS) in murine splenocytes. The levels of pro-inflammatory cytokines [interleukin (IL)-6, tumor necrosis factor-α (TNF-α), IL-12/IL-23(p40) and IL-17A] and anti-inflammatory cytokines [IL-4, IL-10 and interferon-γ (IFN-γ)] were assessed. Incubation of murine splenocytes with acetone+methylene chloride (A+M) and methanol (MeOH) extracts significantly decreased LPS-induced IL-6, IL-12/IL-23(p40) and IL-17A productions after 6 h incubation (p < 0.05). The A+M and MeOH extracts significantly increased LPS-induced IL-4 and IFN-γ productions at 48 and 72 h incubation (p < 0.05). Treatment with A+M extract resulted… More >

Refat Hassan^1,*, Hideo Takagi², Samia Ibrahim³

Journal of Renewable Materials, Vol.8, No.2, pp. 205-218, 2020, DOI:10.32604/jrm.2020.08530

Abstract A spectrophotometric investigation of oxidation of chondroitin-4-sulfate (CS) as a sustainable and biodegradable sulfated macromolecule by oxyanion permanganate ion as multi-equivalent oxidant in acid perchlorate solutions at a constant ionic strength of 2.0 mol dm^-3 has been studied. The experimental results on the influence of the concentration of the reactants the reaction rates revealed first-order dependence in MnO₄^– , fractional second-order in [CS] and fractional first-order with respect to the hydrogen ion concentration. The hydrogen acid concentration dependence of the rate constants indicated that the oxidation rates were increased with increasing the acid concentration which means that the oxidation reaction… More >

Xiaoliang Zhao^1,#, Yuting Wang^1,#, Xiuying Pu¹, Jianzhong Ma¹, Feifan Leng¹, Yonggang Wang¹, Yanling Wang¹, Shuhong Yang¹, Fen Ran², Weijie Zhang^1,*

Journal of Renewable Materials, Vol.7, No.12, pp. 1321-1332, 2019, DOI:10.32604/jrm.2019.07757

Abstract A series of the Guiqi polysaccharides/chitosan/alginate composite hydrogel microspheres (GPcM) with different particle sizes were prepared with Guiqi polysaccharides (GP), chitosan (CS) and sodium alginate (Alg). The optimum preparation process was also determined by single factor and orthogonal experiment analysis. The GPcM were characterized by fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), drug loading efficiency test (LE), encapsulation efficiency test (EE) and in vitro release study. The results showed that the Guiqi polysaccharides chitosan hydrogel (GPCH) and sodium alginate hydrogel (SAH) formed a crossover system in GPcM. The GPcM have a uniform particle size ranging from 395.1μm to… More >

Ma YQ, X Wang, SH Gao, J Zhang

Phyton-International Journal of Experimental Botany, Vol.85, pp. 79-86, 2016, DOI:10.32604/phyton.2016.85.079

Abstract The conditions for extracting polysaccharides from sweet corncobs (SCP) were studied. Four parameters (ratio of water to raw material, compound enzyme concentration, temperature of enzymolysis and duration of enzymolysis) affecting the extraction of SCP were optimized using response surface methodology (RSM). Under the optimized conditions, the yield of SCP was 17.58 %. SCP had inhibitory effects on α-amylase and α-glucosidase activities, and the IC₅₀ was 20.91 mg/mL and 12.47 mg/mL. SCP may therefore have prevention and treatment effects on postprandial hyperglycemia in diabetes. The inhibitory effects of SCP were improved after fractionation, and were strongest in the fraction SCP80. The… More >