Soliman Abdalla^1,2,*, Sherif Kandil², Waleed El-Shirbeeny¹, Fatma Bahabri^1,3

Journal of Renewable Materials, Vol.10, No.9, pp. 2335-2354, 2022, DOI:10.32604/jrm.2022.021211

Abstract Diabetes disorder turns smoothly to be a global epidemic disorder and the glycated hemoglobin (HbA1c) starts to be an efficient marker of it. The dielectric spectroscopy on different human normal- and diabetic-blood samples is used to characterize and to estimate the HbA1c concentration. “dc-” and ac-measurement of the complex conductivity in the temperature range from 280 K up to 320 K, and in the frequency range from one Hz up to 32 MHz have been performed. The thermal activation energy, ΔE_σ, of dc-electric conductivity lies in the range 95 meV < ΔE_σ < 115 meV; while the thermal activation energy,… More >

Sitong Zhou¹, Jiandi Wan^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 70-70, 2019, DOI:10.32604/mcb.2019.06978

Abstract Piezo proteins (Piezo1 and Piezo2) are recently identified mechanically activated cation channels in eukaryotic cells and associated with physiological responses to touch, pressure, and stretch. In particular, human RBCs express Piezo1 on their membranes, and mutations of Piezo1 have been linked to hereditary xerocytosis. To date, however, physiological functions of Piezo1 on normal RBCs remain poorly understood. Here, we show that Piezo1 regulates mechanotransductive release of ATP from human RBCs by controlling the shear-induced Ca2+ influx [1]. We find that, in human RBCs treated with Piezo1 inhibitors or having mutant Piezo1 channels, the amounts of shear-induced ATP release and Ca2+… More >

Ken-ichi Tsubota^1,2,*, Yuya Kodama¹, Hiroyoshi Aoki², Yutaka Yamagata²

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 38-39, 2019, DOI:10.32604/mcb.2019.07285

Abstract We measured a blood flow in a polydimethysiloxane micro channel to reflect the complex geometry of a microvascular network. A flow rate was compared between two working fluids: water and blood. The measured flow rate reflected the bifurcation effects on the apparent viscosity determined by hematocrit, as well as the effects of the surrounding flow channels as bypasses. More >