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  • Open Access

    ARTICLE

    Injectable Collagen/CMC Soft Tissue Filler with Developed Flow Properties

    Reza Samanipour1, Aida Pourmostafa2, Adel Marzban2, Sara Tabatabaee3, Hasan Bahraminasab2, Amir Ali Hamidieh4, Amirhossein Tavakoli4,*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 97-104, 2022, DOI:10.32604/mcb.2022.019080 - 25 March 2022

    Abstract Based on the remarkable demand for facial reconstitute or reshape fillers due to the dermal defects arising from specific diseases, trauma, or aging, several natural or synthetic materials have been investigated. Among the evaluated materials, decellularized dermis is one of the most biocompatible choices for the aim of skin tissue regenerative approaches. On the other hand, Carboxymethyl Cellulose (CMC), a synthetic polysaccharide, with the desirable degradability, biomechanical stability, and nontoxicity seems to be an acceptable reinforcement agent for decellularized dermis. Thus, in this research, an injectable soft tissue filler contained of human-derived decellularized collagen and More >

  • Open Access

    REVIEW

    When wrinkles appear on the immune system can it be reversed?

    Hiba Sibaii1, Salwa Refat El-Zayat1, Mona Khalil2

    European Cytokine Network, Vol.31, No.1, pp. 1-17, 2020, DOI:10.1684/ecn.2020.0441

    Abstract During aging, physiological and physical frailty occur, which is accompanied by a decline in adaptive and innate immunity, termed ‘immunosenescence’ characterized by marked changes in the composition, function, and competence of the human immune system. Moreover, the capabilities of the immune system to defend the human body against infections, to detect and destruct malignant or autoreactive cells decline, resulting in an increase in the susceptibility to infection, development of cancer, as well as autoimmune disorders. The study of age-related changes in immune function is an important area of investigation. In this review, the function of More >

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