FEI XIE^1,2, BAOHONG ZHANG^1,2, WENFENG XU¹, XIAOLING LIAO^1,*, QIUHONG HUANG¹, BO LIU^2,*

BIOCELL, Vol.41, No.2-3, pp. 45-54, 2017, DOI:10.32604/biocell.2017.41.045

Abstract Focal adhesion kinase (FAK) plays a vital role in mediating the adaptability of tumor cells under mechanical stimuli. Previous studies revealed that FAK can locate to different cell compartments, and its regulation is highly dependent on its subcellular localization. However, the local FAK activities and its regulation mechanism in different cell compartments of tumor cells in response to fluid shear stress are still unclear. In this study, 5 dyn/cm² and 20 dyn/cm² of shear stress was applied to HeLa cells for 30 min. The activities of FAK targeting different subcellular compartments (lipids rafts, non-rafts, focal adhesions and cytoplasm) were investigated… More >

Laura Ribba, Jonathan Cimadoro, Silvia Goyanes^*

Journal of Renewable Materials, Vol.7, No.4, pp. 355-363, 2019, DOI:10.32604/jrm.2019.04083

Abstract In this work, conductive polymer nanocomposites were developed based on a biodegradable and biobased polymer (poly (lactic acid)), with the incorporation of only 0.3 wt% of carbon nanotubes (CNTs) to be used as volatile solvent sensors. The correct dispersion of the nanofiller was achieved thanks to a CNT non-covalent modification with an azo-dye (disperse orange 3) which allowed to reach the percolation for electric conduction in values as low as 0.3 wt%. The chemo-resistive properties of the developed sensors were investigated by exposure to organic vapors (ethanol, tetrahydrofuran and toluene) and water vapor, showing good selectivity. In addition, considering the… More >

S. Temiyasathit¹, W-J. Tang¹, C. T. Anderson¹, T. P. Stearns¹, C. R. Jacobs¹

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 215-216, 2006, DOI:10.32604/mcb.2006.003.215

Abstract This article has no abstract. More >

B. Li¹, L. Xie¹, Z. C. Starr¹, Z. Yang¹, J. H-C. Wang^1*

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 195-196, 2006, DOI:10.32604/mcb.2006.003.195

Abstract This article has no abstract. More >

Xi Liu, Xinjun Dong, Yang Wang^*, Jacob Dodson, Bryan Joyce

Sound & Vibration, Vol.52, No.3, pp. 6-11, 2018, DOI:10.32604/sv.2018.03857

Abstract This article reports the latest development of a wireless sensing system, named Martlet, on high-g shock acceleration measurement. The Martlet sensing node design is based on a Texas Instruments Piccolo microcontroller, with clock frequency programmable up to 90 MHz. The high clock frequency of the microcontroller enables Martlet to support high-frequency data acquisition and high-speed onboard computation. In addition, the extensible design of the Martlet node conveniently allows incorporation of multiple sensor boards. In this study, a high-g accelerometer interface board is developed to allow Martlet to work with the selected microelectromechanical system (MEMS) high-g accelerometers. Besides low-pass and high-pass… More >

Christopher A. Lemmon^1,2, Nathan J. Sniadecki³, Sami Alom Ruiz^1,3, John L. Tan, Lewis H. Romer^2,4,5, Christopher S. Chen^3,4

Molecular & Cellular Biomechanics, Vol.2, No.1, pp. 1-16, 2005, DOI:10.3970/mcb.2005.002.001

Abstract The interplay of mechanical forces between the extracellular environment and the cytoskeleton drives development, repair, and senescence in many tissues. Quantitative definition of these forces is a vital step in understanding cellular mechanosensing. Microfabricated post array detectors (mPADs) provide direct measurements of cell-generated forces during cell adhesion to extracellular matrix. A new approach to mPAD post labeling, volumetric imaging, and an analysis of post bending mechanics determined that cells apply shear forces and not point moments at the matrix interface. In addition, these forces could be accurately resolved from post deflections by using images of post tops and bases. Image… More >

A. Tsourkas, R. Weissleder^1,1

Molecular & Cellular Biomechanics, Vol.1, No.2, pp. 133-146, 2004, DOI:10.3970/mcb.2004.001.133

Abstract Traditionally, fluorescent and luminescent reporter proteins have been used as indicators of gene expression and protein localization. However, insightful mutagenesis and protein engineering strategies have transformed these simple passive reporters into active biological sensors. Molecular reporters are now being designed to alter their intrinsic optical properties in response to specific biomolecular interactions. Applications for these novel biological sensors range from monitoring intracellular pH and ion fluxes to detecting protein-protein interactions and enzymatic activity. The ability to monitor the dynamics of intracellular activity in response to external stimuli can help elucidate the cascade of events involved in complex processes such as… More >

Jessica E. Koehne, Jun Li¹, Alan M. Cassell, Hua Chen, Qi Ye, Jie Han, M. Meyyappan

Molecular & Cellular Biomechanics, Vol.1, No.1, pp. 69-80, 2004, DOI:10.3970/mcb.2004.001.069

Abstract Vertically aligned multi-walled carbon nanotubes (MWCNTs) have been reported in fabricating nanoelectrode arrays. Further studies on optimizing this system for the development of ultrasensitive DNA sensors are reported here. The mechanical stability of the as-grown MWCNT array can be improved by polymer coating or SiO₂ encapsulation. The latter method provides excellent electronic and ionic insulation to the sidewall of MWCNTs and the underlying metal layer, which is investigated with electrochemical impedance spectroscopy. The insulation ensures well-defined nanoelectrode behavior. A method is developed for selectively functionalizing biomolecules at the open end of MWCNTs while keeping the SiO₂ surface passivated, using the… More >

Longqing Zhang¹, Liping Bai^1,*, Xinwei Zhang², Yanghong Zhang², Lei Yang¹, Xiangdu Yan²

CMC-Computers, Materials & Continua, Vol.61, No.2, pp. 817-828, 2019, DOI:10.32604/cmc.2019.06062

Abstract The drawbacks of the traditional multi-hop structure of wireless sensor networks (WSNS) are susceptible to reflection, scattering and diffraction, serious attenuation of signal intensity and phase deviation due to various obstacles in cultivated land environment and mountains. In this paper, the wireless signal intensity is measured and curve fitting is done respectively in both open environment and obstacle-environment with both sending and receiving height of 0 m, 1 m, and 2 m. It is found out that packet loss probability is too high when an obstacle exists. In such a case, unmanned aerial vehicle (UAV) is introduced to activate terrestrial… More >

Weidong Fang¹, Wuxiong Zhang^1,2,*, QianQian Zhao^1,2, Xiaohong Ji³, Wei Chen⁴, Biruk Assefa⁵

CMC-Computers, Materials & Continua, Vol.61, No.2, pp. 583-599, 2019, DOI:10.32604/cmc.2019.05237

Abstract As an Industrial Wireless Sensor Network (IWSN) is usually deployed in a harsh or unattended environment, the privacy security of data aggregation is facing more and more challenges. Currently, the data aggregation protocols mainly focus on improving the efficiency of data transmitting and aggregating, alternately, the aim at enhancing the security of data. The performances of the secure data aggregation protocols are the trade-off of several metrics, which involves the transmission/fusion, the energy efficiency and the security in Wireless Sensor Network (WSN). Unfortunately, there is no paper in systematic analysis about the performance of the secure data aggregation protocols whether… More >