Dennis Bäcker¹, Andreas Ricoeur², Meinhard Kuna¹

Structural Durability & Health Monitoring, Vol.7, No.1&2, pp. 1-22, 2011, DOI:10.3970/sdhm.2011.007.001

Abstract A new sensor concept for monitoring fatigue crack growth in technical structures is presented. It allows the in-situ determination of the position of the crack tip as well as the fracture mechanical quantities. The required data are obtained from a piezoelectric polymer film, which is attached to the surface of the monitored structure. The stress intensity factors and the crack tip position are calculated from electrical potentials obtained from a sensor array by solving the non-linear inverse problem. More >

Qin Peng¹, Shaoying Lu¹, Shu Chien¹, Yingxiao Wang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 83-83, 2019, DOI:10.32604/mcb.2019.07385

Abstract The dramatic re-organization of chromatin during mitosis is perhaps one of the most fundamental of all cell processes [1,2]. It remains unclear how epigenetic histone modifications, despite their crucial roles in regulating chromatin architectures, are dynamically coordinated with chromatin reorganization in controlling this process. Mechanical cues have also been shown to play important roles in modulating gene expressions and cellular functions [3,4]; however, it is still unclear about the mechanical regulations of epigenetics and chromatin organization. In this study, we have developed and characterized biosensors with high sensitivity and specificity based on fluorescence resonance energy transfer (FRET). These biosensors were… More >

Longwei Liu¹, Praopim Limsakul¹, Shaoying (Kathy) Lu¹, Peter Yingxiao Wang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 82-82, 2019, DOI:10.32604/mcb.2019.07360

Abstract Genetically-encoded biosensors based on Fluorescence Resonance Energy Transfer (FRET biosensors) have been widely used to dynamically track the activity of Protein Tyrosine Kinases (PTKs) in living cells because of their sensitive ratiometric fluorescence readout, high spatiotemporal resolution. However, the limitation in sensitivity, specificity, and dynamic range of these biosensors have hindered their broader applications, and there was a lack of efficient ways to optimize FRET biosensors. Here we established a rapid, systematic and universal approach for FRET biosensor optimization through directed evolution which involves generating genetic diversity and screening for protein variants with desired properties at the same time and… More >

Na Liu¹, Xiaoyun Zhang², Yuzhen Ding², Hong Li², Xiumei Guan², Min Cheng^2,*, Xiaodong Cui^2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 87-87, 2019, DOI:10.32604/mcb.2019.05751

Abstract Objective: Endothelial progenitor cells (EPCs) play a vital role in postnatal vascular injury and repair, especially vasculogenesis and angiogenesis. The purpose of this study was to investigate the effect of laminar shear stress in attenuating the decreased-expression of complement regulatory protein CD59 and the mechanism of cytoskeleton F-actin. Methods: EPCs were isolated from human umbilical vein blood and planted on glass slides, which applied to the laminar shear stress force (12 dyne/cm2) in a high glucose (20 mM) culture environment. The gene and protein expression of CD59 were detected by SYBGreen quantitative PCR and fluorescence activated cell sorter (FACS) respectively.… More >

V. Mallardo^1,2, M.H. Aliabadi³

Structural Durability & Health Monitoring, Vol.9, No.4, pp. 287-323, 2013, DOI:10.32604/sdhm.2013.009.287

Abstract The optimum location of the sensors is a critical issue of any successful Structural Health Monitoring System. Sensor optimization problems encompass mainly three areas of interest: system identification, damage identification and impact identification. The current paper is intended as a review of the state of the art at the year 2012 and going back to 1990. The above topics have been dealt with in separate contexts so far but they contain interesting common elements to be exploited. More >

A. Rama Mohan Rao¹, S. Krishna Kumar¹, K. Lakshmi¹

Structural Durability & Health Monitoring, Vol.8, No.3, pp. 271-294, 2012, DOI:10.32604/sdhm.2012.008.271

Abstract Current advancements in structural health monitoring, sensor and sensor network technologies have encouraged using large number of sensor networks in monitoring spatially large civil structures like bridges. Large amount of spatial information obtained from these sensor networks will enhance the reliability in truly assessing the state of the health of the structure. However, if sensors go faulty during operation, the feature extraction techniques embedded into SHM scheme may lead to an erroneous conclusion and often end up with false alarms. Hence it is highly desirable to robustly detect the faulty sensors, isolate and correct the data, if the data at… More >

Ramana M. Pidaparti¹, Ashwin Belle², Ju Wang³

Structural Durability & Health Monitoring, Vol.5, No.4, pp. 295-310, 2009, DOI:10.3970/sdhm.2009.005.295

Abstract This paper presents the development of a portable integrated wireless sensor module with video camera and ultrasound capabilities to monitor and investigate corrosion damage "in" structures. There are many studies in the literature on structural health monitoring with various sensors systems. However, very few of them utilize low power devices with reliable wireless communication capability to support data-intensive sensing which is a critical issue for practical applications. In this study, we developed a wireless sensor module with video camera capabilities and integrated it with a damage analysis module to investigate the damage of a structure. The module provides an open… More >

S.P.L. Leme¹, M.H. Aliabadi², L.M. Bezerra¹, P.W. Partridge¹

Structural Durability & Health Monitoring, Vol.3, No.3, pp. 121-132, 2007, DOI:10.3970/sdhm.2007.003.121

Abstract The coupled electromechanical behaviour of a thin piezoceramic sensor bonded to a stiffened panel subjected to membrane mechanical loadings is examined. The sensor is characterised by an electrostatic line model bonded to a damaged panel modelled by the dual boundary element method. Numerical results obtained demonstrate that the proposed method is capable of modelling changes in the signal output due to presence of cracks. Also presented is a numerical model for detecting fatigue crack growth in a stiffened panel using piezoceramic sensors. More >

Qi Wang^1,*, Wei Liu¹, Hualong Yu¹, Shang Zheng¹, Shang Gao¹, Fabrizio Granelli²

CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.1, pp. 83-103, 2019, DOI:10.32604/cmes.2019.06897

Abstract The wireless sensor network (WSN) is widely employed in the application scenarios of the Internet of Things (IoT) in recent years. Extending the lifetime of the entire system had become a significant challenge due to the energy-constrained fundamental limits of sensor nodes on the perceptual layer of IoT. The clustering routing structures are currently the most popular solution, which can effectively reduce the energy consumption of the entire network and improve its reliability. This paper introduces an enhanced hybrid intelligential algorithm based on particle swarm optimization (PSO) and ant colony optimization (ACO) method. The enhanced PSO is deployed to select… More >

FEI XIE^1,2, BAOHONG ZHANG^1,2, WENFENG XU¹, XIAOLING LIAO^1,*, QIUHONG HUANG¹, BO LIU^2,*

BIOCELL, Vol.41, No.2-3, pp. 45-54, 2017, DOI:10.32604/biocell.2017.41.045

Abstract Focal adhesion kinase (FAK) plays a vital role in mediating the adaptability of tumor cells under mechanical stimuli. Previous studies revealed that FAK can locate to different cell compartments, and its regulation is highly dependent on its subcellular localization. However, the local FAK activities and its regulation mechanism in different cell compartments of tumor cells in response to fluid shear stress are still unclear. In this study, 5 dyn/cm² and 20 dyn/cm² of shear stress was applied to HeLa cells for 30 min. The activities of FAK targeting different subcellular compartments (lipids rafts, non-rafts, focal adhesions and cytoplasm) were investigated… More >