Magdy M. Fadel^1,*, Sally M. El-Ghamrawy², Amr M. T. Ali-Eldin¹, Mohammed K. Hassan³, Ali I. El-Desoky¹

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 2293-2312, 2022, DOI:10.32604/cmc.2022.028287 - 16 June 2022

Abstract Distributed denial-of-service (DDoS) attacks are designed to interrupt network services such as email servers and webpages in traditional computer networks. Furthermore, the enormous number of connected devices makes it difficult to operate such a network effectively. Software defined networks (SDN) are networks that are managed through a centralized control system, according to researchers. This controller is the brain of any SDN, composing the forwarding table of all data plane network switches. Despite the advantages of SDN controllers, DDoS attacks are easier to perpetrate than on traditional networks. Because the controller is a single point of More >

FEIFEI TIAN¹, HUAN HU¹, DI WANG¹, HUAN DING¹, QINGJIA CHI², HUAPING LIANG³, WENLI ZENG^4,*

BIOCELL, Vol.46, No.10, pp. 2291-2301, 2022, DOI:10.32604/biocell.2022.020198 - 13 June 2022

Abstract This study used transcriptome and epigenetic data to predict the prognosis of immune-related genes (IRGs) Apelin (APLN) in patients with hepatocellular carcinoma (HCC). The TCGA database has gene expression and clinical data for HCC. And DNA methylation 450 k data for HCC was download from the University of California Santa Cruz (UCSC) Xena browser. Performing clinical and prognostic analysis of APLN expression, results show that APLN is highly expressed in tumor samples. And it has an increasing trend with the development of clinical stage and T stage. To explore the prognostic role of APLN, the… More >

HUILI ZHU¹, LINA XIAO¹, XIA YIN¹, SHIBING XIANG¹, CHUNHUI WANG^2,*

BIOCELL, Vol.46, No.10, pp. 2241-2256, 2022, DOI:10.32604/biocell.2022.020389 - 13 June 2022

Abstract Pancreatic ductal adenocarcinoma (PDAC) is highly heterogeneous, making its prognosis prediction difficult. The arachidonic acid (AA) cascade is involved in carcinogenesis. Therefore, the metabolic enzymes of the AA cascade consist of lipoxygenases (LOXs), phospholipase A2s (PLA2s), and cyclooxygenases (COXs) along with their metabolic products, including leukotrienes. Nevertheless, the prognostic potential of AA metabolism-associated PDAC has not been explored. Herein, the mRNA expression patterns and the matching clinical information of individuals with PDAC were abstracted from online data resources. We employed the LASSO Cox regression model to develop a multigene clinical signature in the TCGA queue.… More >

Tsung-Yu Lu¹, Mu-En Wu², Er-Hao Chen³, Yeong-Luh Ueng^4,*

CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 935-952, 2022, DOI:10.32604/cmc.2022.026717 - 18 May 2022

Abstract This paper presents an off-line handwritten signature verification system based on the Siamese network, where a hybrid architecture is used. The Residual neural Network (ResNet) is used to realize a powerful feature extraction model such that Writer Independent (WI) features can be effectively learned. A single-layer Siamese Neural Network (NN) is used to realize a Writer Dependent (WD) classifier such that the storage space can be minimized. For the purpose of reducing the impact of the high intraclass variability of the signature and ensuring that the Siamese network can learn more effectively, we propose a More >

Tuan Nguyen Kim^1,*, Duy Ho Ngoc², Nikolay A. Moldovyan³

CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 783-799, 2022, DOI:10.32604/cmc.2022.024677 - 18 May 2022

Abstract The representative collective digital signature scheme allows the creation of a unique collective signature on document M that represents an entire signing community consisting of many individual signers and many different signing groups, each signing group is represented by a group leader. On document M, a collective signature can be created using the representative digital signature scheme that represents an entire community consisting of individual signers and signing groups, each of which is represented by a group leader. The characteristic of this type of letter is that it consists of three elements (U, E, S),… More >

Tuan Nguyen Kim^1,*, Duy Ho Ngoc², Nikolay A. Moldovyan³

CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 595-610, 2022, DOI:10.32604/cmc.2022.023168 - 18 May 2022

Abstract There have been many digital signature schemes were developed based on the discrete logarithm problem on a finite field. In this study, we use the elliptic curve discrete logarithm problem to build new collective signature schemes. The cryptosystem on elliptic curve allows to generate digital signatures with the same level of security as other cryptosystems but with smaller keys. To extend practical applicability and enhance the security level of the group signature protocols, we propose two new types of collective digital signature schemes based on the discrete logarithm problem on the elliptic curve: i) the More >

Yuzhen Liu^1,2, Xiaoliang Wang^1,2,*, Zhoulei Cao^1,2, Frank Jiang³

Journal of Cyber Security, Vol.4, No.1, pp. 57-64, 2022, DOI:10.32604/jcs.2022.028792 - 05 May 2022

Abstract Vehicular ad hoc network (VANET) is a self-organizing wireless sensor network model, which is extensively used in the existing traffic. Due to the openness of wireless channel and the sensitivity of traffic information, data transmission process in VANET is vulnerable to leakage and attack. Authentication of vehicle identity while protecting vehicle privacy information is an advantageous way to improve the security of VANET. We propose a scheme based on fair blind signature and secret sharing algorithm. In this paper, we prove that the scheme is feasible through security analysis. More >

Yanan Chen^1,2,3,4, Ting Yao^1,4,*, Haiping Ren², Zehao Gan¹

CMES-Computer Modeling in Engineering & Sciences, Vol.131, No.3, pp. 1497-1513, 2022, DOI:10.32604/cmes.2022.019589 - 19 April 2022

Abstract The introduction of the electronic medical record (EHR) sharing system has made a great contribution to the management and sharing of healthcare data. Considering referral treatment for patients, the original signature needs to be converted into a re-signature that can be verified by the new organization. Proxy re-signature (PRS) can be applied to this scenario so that authenticity and nonrepudiation can still be insured for data. Unfortunately, the existing PRS schemes cannot realize forward and backward security. Therefore, this paper proposes the first PRS scheme that can provide key-insulated property, which can guarantee both the… More >

Yongli Tang¹, Yuanhong Li¹, Qing Ye^1,*, Ying Li¹, Xiaojun Wang²

CMC-Computers, Materials & Continua, Vol.72, No.2, pp. 4069-4085, 2022, DOI:10.32604/cmc.2022.026820 - 29 March 2022

Abstract Although the existing group signature schemes from lattice have been optimized for efficiency, the signing abilities of each member in the group are relatively single. It may not be suitable for complex applications. Inspired by the pioneering work of Bellare and Fuchsbauer, we present a primitive called policy-based group signature. In policy-based group signatures, group members can on behalf of the group to sign documents that meet their own policies, and the generated signatures will not leak the identity and policies of the signer. Moreover, the group administrator is allowed to reveal the identity of… More >

JUNXIA LIU¹, KE PANG², FEI HE^2,*

BIOCELL, Vol.46, No.7, pp. 1661-1673, 2022, DOI:10.32604/biocell.2022.018023 - 17 March 2022

Abstract Breast cancer is one of the most common cancers in the world and seriously threatens the health of women worldwide. Prognostic models based on immune-related genes help to improve the prognosis prediction and clinical treatment of breast cancer patients. In the study, we used weighted gene co-expression network analysis to construct a co-expression network to screen out highly prognostic immune-related genes. Subsequently, the prognostic immune-related gene signature was successfully constructed from highly immune-related genes through COX regression and LASSO COX analysis. Survival analysis and time receiver operating characteristic curves indicate that the prognostic signature has More >