ARTEM P. GUREEV¹, IRINA S. SADOVNIKOVA¹, EKATERINA V. CHERNYSHOVA¹, EKATERINA P. KRUTSKIKH¹, IRINA B. PEVZNER², LJUBAVA D. ZOROVA², VERONIKA V. NESTEROVA¹, POLINA I. BABENKOVA¹, EGOR Y. PLOTNIKOV^2,*

BIOCELL, Vol.49, No.5, pp. 873-892, 2025, DOI:10.32604/biocell.2025.063557 - 27 May 2025

Abstract Background: Mitochondrial dysfunction plays a critical role in the pathogenesis of Alzheimer’s disease (AD). Resveratrol is a promising compound for the treatment of various neurodegenerative diseases, including AD. Aims: To investigate mitochondrial damage and the effects of resveratrol on inflammation, cognitive function, and mitochondrial quality control in APP/PS1 mice. Methods: Comparative analysis of mitochondrial DNA (mtDNA) damage was conducted between 10-month-old APP/PS1 mice and age-matched C57BL/6 mice. Assessments included measurement of amyloid-β levels, inflammatory markers, swimming distance in the Morris water maze, and gut microbiome composition. Resveratrol’s effects on cytokine expression, mtDNA levels in plasma, and… More >

Muhammad Usman Ghani Khan^1,2, Zubaira Naz¹, Javeria Khan¹, Tanzila Saba³, Ibrahim Abunadi³, Amjad Rehman³, Usman Tariq^4,*

CMC-Computers, Materials & Continua, Vol.68, No.2, pp. 2363-2376, 2021, DOI:10.32604/cmc.2021.014550 - 13 April 2021

Abstract The National Health Interview Survey (NHIS) shows that there are 13.2% of children at the age of 11 to 17 who are suffering from Attention Deficit Hyperactivity Disorder (ADHD), globally. The treatment methods for ADHD are either psycho-stimulant medications or cognitive therapy. These traditional methods, namely therapy, need a large number of visits to hospitals and include medication. Neurogames could be used for the effective treatment of ADHD. It could be a helpful tool in improving children and ADHD patients’ cognitive skills by using Brain–Computer Interfaces (BCI). BCI enables the user to interact with the… More >