Mohamed Ammar^1,*, Alireza Mousavi¹, Hamed Al-Raweshidy^2,*

Digital Engineering and Digital Twin, Vol.2, pp. 1-31, 2024, DOI:10.32604/dedt.2023.044930

Abstract The advent of technology around the globe based on the Internet of Things, Cloud Computing, Big Data, Cyber-Physical Systems, and digitalisation. This advancement introduced industry 4.0. It is challenging to measure how enterprises adopt the new technologies. Industry 4.0 introduced Digital Twins, given that no specific terms or definitions are given to Digital Twins still challenging to define or conceptualise the Digital Twins. Many academics and industries still use old technologies, naming it Digital Twins. This young technology is in danger of reaching the plateau despite the immense benefit to sectors. This paper proposes a novel and unique definition for… More >

Fengping Li¹, Dong Sun^1,*, Qiaolin Zhang^1,2,3, Hairong Chen^1,2,3, István Bíró^2,3, Zhiyi Zheng⁴, Yaodong Gu^1,*

Molecular & Cellular Biomechanics, Vol.20, No.1, pp. 35-47, 2023, DOI:10.32604/mcb.2023.041016

Abstract Background: A children’s backpack is one of the important school supplies for school-age children. Long-term excessive weight can cause spinal deformity that cannot be reversed. This study compared a double helical spring decompression structure backpack (DHSB) with a traditional backpack (TB) to explore the optimization of decompression devices on upper body pressure. The finite element (FE) method was then used to explore the simulation of lumbar stress with different backpacks, in order to prove that DHSB can reduce the influence of backpack weight on lumbar vertebrae, avoid the occurrence of muscle discomfort and spinal deformity in children; Methods: 18 male… More > Graphic Abstract

Xiaotian Liang^1,#, Qi Wen^1,#, Rui Luo¹, Yanxin Zhang¹, Mingda Yin¹, Yanpeng Wen¹, Xuemei Hu¹, Zhiyan Wang¹, Yumiao Huo¹, Fenglan Huang^{1,2,3,4,5,6,*}

Phyton-International Journal of Experimental Botany, Vol.92, No.6, pp. 1765-1792, 2023, DOI:10.32604/phyton.2023.026935

Abstract Castor bean (Ricinus communis L.), is one of the top 10 oilseed crops in the world and, therefore, of high economic value. Hybridization is one of the most effective ways to breed new varieties with high yield, high oil content, and better stress resistance. Therefore, prediction of desired traits in castor hybrid offspring is particularly important. In this study, proteomic analysis was performed to identify differentially expressed proteins (DEPs) in seeds between castor hybrid offspring and their female (Lm female line aLmAB₂) and male parents (CSR·181). Among the DEPs upregulated in the seeds of hybrid offspring, the majority were related… More >

FABIANA ROCHA ARAÚJO¹, BRUNO MACHADO BERTASSOLI², ISABELLA CRISTINA SOUZA FÉLIX¹, DOUGLAS MARINHO ABREU¹, NATáLIA MELO OCARINO¹, AMANDA MARIA SENA REIS³, JUNEO FREITAS SILVA⁴, ROGéRIA SERAKIDES^1,*

BIOCELL, Vol.47, No.2, pp. 423-430, 2023, DOI:10.32604/biocell.2023.023689

Abstract To evaluate the characteristics and synthesis activity of osteoblasts extracted from the calvaria of offspring of rats exposed to maternal hyperthyroidism. Twelve adult Wistar rats were divided into two groups, one control and one treated with daily administration of L-thyroxine by an orogastric tube (50 µg/animal/day) during pregnancy. Three days after delivery and confirmation of the mothers’ hyperthyroidism, the offspring were euthanized for the extraction of osteoblasts from the calvaria. At 7, 14, and 21 days, proliferation activity was assessed using MTT assay, while alkaline phosphatase (ALP) activity was assessed by the BCIP/NBT method. At 21 days, the total area… More >

Hongly Va¹, Min-Hyung Choi², Min Hong^3,*

CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 831-848, 2022, DOI:10.32604/cmc.2022.029576

Abstract This paper presents a parallel method for simulating real-time 3D deformable objects using the volume preservation mass-spring system method on tetrahedron meshes. In general, the conventional mass-spring system is manipulated as a force-driven method because it is fast, simple to implement, and the parameters can be controlled. However, the springs in traditional mass-spring system can be excessively elongated which cause severe stability and robustness issues that lead to shape restoring, simulation blow-up, and huge volume loss of the deformable object. In addition, traditional method that uses a serial process of the central processing unit (CPU) to solve the system in… More >

MIN CHEN^1,#, YUAN HUANG^2,#, WEN XU², CHUNLIN SU^2,*

BIOCELL, Vol.46, No.6, pp. 1505-1519, 2022, DOI:10.32604/biocell.2022.016564

Abstract The development of polycystic ovary syndrome (PCOS) is closely related to the chronic inflammatory and obese. Recent studies have found macrophages regulate the chronic inflammation and adipose tissue remodelling, but the underlying mechanisms have not been clarified. In this study, we established a model of PCOS in the offspring rats by high androgen exposure during late pregnancy in parental and established a female rat macrophage eliminating model by rejection of clodronate liposome. Then, the offspring rat macrophage phenotype in offspring female rat adipose tissue, and levels of testosterone, angiogenic factors (PDGF and VEGF) and inflammatory factors (TNF-α and MCP-1) were… More >

Hongly Va¹, Min-Hyung Choi², Min Hong^3,*

Computer Systems Science and Engineering, Vol.41, No.2, pp. 427-443, 2022, DOI:10.32604/csse.2022.020685

Abstract The primary goal of cloth simulation is to express object behavior in a realistic manner and achieve real-time performance by following the fundamental concept of physic. In general, the mass–spring system is applied to real-time cloth simulation with three types of springs. However, hard spring cloth simulation using the mass–spring system requires a small integration time-step in order to use a large stiffness coefficient. Furthermore, to obtain stable behavior, constraint enforcement is used instead of maintenance of the force of each spring. Constraint force computation involves a large sparse linear solving operation. Due to the large computation, we implement a… More >

PAOLA GRIMALDI^*

BIOCELL, Vol.46, No.2, pp. 301-304, 2022, DOI:10.32604/biocell.2022.017588

Abstract Cannabis is the most widely used drug in the Western societies particularly among adolescent and young adults. Epidemiological studies demonstrate that men use cannabis more frequently than women with higher risk in developing cannabis-related disorders. Although the direct adverse effects of cannabis on male reproductive functions have been studied both in humans and animal models, the possible long-term risks for the health of the users and their offspring are still an area of active research. More >

Xiaorui Zhang^1,2,*, Tong Xu¹, Wei Sun², Jiali Duan¹, Sunil Kumar Jha³

CMC-Computers, Materials & Continua, Vol.69, No.1, pp. 727-745, 2021, DOI:10.32604/cmc.2021.018182

Abstract In the simulation of acupuncture manipulation, it is necessary to accurately capture the information of acupuncture points and particles around them. Therefore, a soft tissue modeling method that can accurately track model particles is needed. In this paper, a soft tissue acupuncture model based on the mass-spring force net is designed. MSM is used as the auxiliary model and the SHF model is combined. SHF is used to establish a three-layer soft tissue model of skin, fat, and muscle, and a layer of the MSM based force network is covered on the surface of soft tissue to realize the complementary… More >

Xiaorui Zhang^1,2,*, Jiali Duan¹, Wei Sun², Tong Xu¹, Sunil Kumar Jha³

CMES-Computer Modeling in Engineering & Sciences, Vol.127, No.1, pp. 117-133, 2021, DOI:10.32604/cmes.2021.012034

Abstract The cutting simulation of soft tissue is important in virtual surgery. It includes three major challenges in computation: Soft tissue simulation, collision detection, and handling, as well as soft tissue models. In order to address the earlier challenges, we propose a virtual cutting system based on the mass-spring model. In this system, MSM is utilized to simulate the soft tissue model. Residual stress is introduced to the model for simulating the shrinking effect of soft tissue in cutting. Second, a cylinder-based collision detection method is used to supervise the collision between surgical tools and soft tissue. Third, we simulate the… More >