Da Li^1,#, Liqing Peng^2,#, Yi Wang³, Ding Yuan⁴, Tinghui Zheng^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 39-39, 2019, DOI:10.32604/mcb.2019.05718

Abstract Objective: Thoracic endovascular aortic repair (TEVAR) of type B aortic dissection (AD) is to initiate the thrombosis in the false lumen to eventually result in aortic remodeling. We aim to find out whether the false lumen (FL) thrombosis rate after TEVAR can be predicted accurately by an index that expresses the degree of aortic arch angulation. Method: Three-dimensional aortic arch geometry of 39 type B AD patients (mean age: 48 years) after TEVR were reconstructed from post-operative CT images. For the first time, the question mark which takes into account the curvature of both aortic arch and the descending aorta… More >

Xudong Liu¹, Yunhan Cai¹, Bing Jia², Shengzhang Wang^1,*, Guanghong Ding¹

CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.2, pp. 215-228, 2018, DOI: 10.31614/cmes.2018.04158

Abstract Our study evaluated the hemodynamic performance of an axial flow blood pump surgically implanted in idealized total cavopulmonary connection (TCPC) models. This blood pump was designed to augment pressure from the inferior vena cava (IVC) to the pulmonary circulation. Two Fontan procedures with single and bilateral superior vena cava (SVC) were compared to fit the mechanical supported TCPC physiologies. Computational fluid dynamics (CFD) analyses of two Pump-TCPC models were performed in the analyses. Pressure-flow characteristics, energy efficiency, fluid streamlines, hemolysis and thrombosis analyses were implemented. Numerical simulations indicate that the pump produces pressure generations of 1 mm to 24 mm… More >

Guangliang Pan¹, Yu Chang^1,*, Mingrui Fu¹

CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.2, pp. 199-213, 2018, DOI: 10.31614/cmes.2018.04080

Abstract Patients with extracorporeal membrane oxygenation still suffer from high rates of complication that linked to the flow field within the blood pump. So it is essential to optimise the geometry of the pump. The specification of shroud design is arguably the necessary design parameter in the centrifugal pump. However, the hemodynamic performances of the different shroud designs have not been studied extensively. In this study, ten different shroud designs were made and divided into two groups as the different covering locations (A: Covering the blade leading edge, B: Covering the blade trailing edge). In every group, six shroud designs with… More >