Amr Mansour¹, Noha M. Gamal^2,*, Alaa M. Nady³, Amr Ibraheem³, Dalia M. Salah⁴, Khaled M. El-Maghraby²

Congenital Heart Disease, Vol.18, No.6, pp. 679-691, 2023, DOI:10.32604/chd.2023.020028

Abstract Background: Closure of an atrial septal defect (ASD) reduces right-side heart volumes by abolishing shunting with simultaneous improvement of the left ventricle (LV) filling and functions due to ventricular interdependence, thereby improving symptoms. Furthermore, studies conducted on atrial volume changes after ASD closure are limited. Cardiac magnetic resonance (CMR) is considered as the gold standard method for measuring cardiac volume and mass. Objective: We aimed to study the effect of transcatheter and surgical closure of secundum ASD on cardiac volumes and systolic functions as well as the fate of tricuspid regurgitation (TR), using CMR analysis. Methods: We prospectively enrolled 30… More >

Yifan Li¹, Zewen Chen², Yumei Xie¹, Shushui Wang¹, Zhiwei Zhang^1,*

Congenital Heart Disease, Vol.18, No.4, pp. 413-430, 2023, DOI:10.32604/chd.2023.029848

Abstract Background: Limited data are available regarding intermediate and long-term outcomes of transcatheter closure (TCC) of coronary cameral fistulas (CCFs) in the pediatric patients. Methods: All pediatric patients diagnosed with CCFs who were scheduled to undergo TCC between 2005 and 2019 were retrospectively enrolled in the study. Results: A total of 66 patients (median age: 3.93 years, median weight: 15 kg) underwent attempted TCC of CCFs. Immediate successful device implantation was achieved in 62 patients, and immediate complete occlusion was achieved in 44 patients (44/62%, 71.0%). The closure procedure was waived in 2 patients due to anatomical factors. A total of 6… More >

Xingbang Li^1,#, Xuan Zheng^2,#, Bowen Jin¹, Yunyan Li¹, Yongyu Shao¹, Xiaoxian Deng¹, Dingyang Li¹, Shanshan Li¹, Hongmei Zhou¹, Jie Zhang³, Xianya Zhang⁴, Qunshan Shen¹, Gangcheng Zhang^2,*

Congenital Heart Disease, Vol.18, No.3, pp. 373-385, 2023, DOI:10.32604/chd.2023.028979

Abstract Background: Transcatheter closure of patent foramen ovale (PFO) has been widely accepted as a highly effective way to treat high-risk PFO-related diseases. However, traditional non-degradable occluders made of metal alloys will permanently exist in the body, resulting in thrombosis, valve damage, hemolysis, arrhythmia, or other complications. The biodegradable PFO occluder developed by Shanghai Mallow Medical Instrument Co., Ltd., China can be fully absorbed and degrade into nontoxic ingredients, reducing postoperative complications. Objectives: To study the safety and efficacy of biodegradable PFO occluders in treating PFO. Methods: This single-center clinical trial collected 30 patients treated with a biodegradable PFO occluder. The… More > Graphic Abstract

Ivana B. Cerović¹, Vladislav A. Vukomanović^1,2, Jovan Lj. Košutić^1,2, Mila S. Stajević^1,2, Sanja S. Ninić¹, Saša S. Popović¹, Ivan D. Dizdarević¹, Staša D. Krasić¹, Sergej M. Prijić^1,2,*

Congenital Heart Disease, Vol.18, No.3, pp. 361-371, 2023, DOI:10.32604/chd.2023.026533

Abstract Introduction: Transcatheter closure is an alternative to ventricular septal defect (VSD) occlusion surgery. Nit-Occlud Lê VSD coil is a new device yet to be evaluated. The study aimed to evaluate immediate and midterm results after transcatheter closure with the Nit-Occlud Lê VSD device. Methods: The retrospective analysis included 30 patients with VSD referred for closure during the period from October 2015 to December 2020. Results: At the time of intervention, the patients’ mean age and body weights were 7.5 ± 5.6 years and 29.3 ± 19.1 kg. The majority of the defects had perimembranous location (24/30), four defects had muscular and two outlet subaortic position.… More >

Rohan Suresh Daniel^1,2, Georgia K. Schmidt^1,2, Hayato Nakanishi^1,2, Karen Smayra^1,2, Mariah N. Mascara^1,2, Dilip K. Vankayalapati^1,2, Reem H. Matar^1,2,3, Christian A. Than^1,2,4, George Shiakos⁵, Ioannis Tzanavaros^2,5,*

Congenital Heart Disease, Vol.18, No.2, pp. 245-265, 2023, DOI:10.32604/chd.2023.027596

Abstract Background: Persistent patent ductus arteriosus (pPDA) is a common condition in preterm infants. This meta-analysis aimed to assess the safety and efficacy of transcatheter closure (TC) when compared to surgical ligation (SL) in preterm infants with pPDA. Methods: A literature search of Ovid Cochrane Library, Medline, Embase, Epub, Scopus, PMC Preprints, and was conducted from inception to May 06, 2022. Eligible studies reported infants diagnosed with pPDA born at ≤2000 g birth weight or at ≤37 weeks’ who underwent TC or SL as treatment. This review was registered in PROSPERO (CRD42022325944). Results: From 97 studies screened, 8 studies met the… More >

Jingnan Zhang¹, Junyi Wan¹, Yihang Li², Yu Han², Jiahua Pan³, Fang Fang¹, Shiliang Jiang⁴, Xiangbin Pan¹, Gejun Zhang^1,*

Congenital Heart Disease, Vol.18, No.2, pp. 219-234, 2023, DOI:10.32604/chd.2023.027562

Abstract Background: The Venus-P valve was the first self-expanding valve used world-wide for transcatheter pulmonary valve replacement (TPVR) in patients with severe pulmonary regurgitation (PR). We intended to report the extended follow-up results from the prospective trial (No. NCT02590679). Methods: A total of 38 patients with severe PR (mean age 24.2 ± 13.2) were included. Follow-up data were obtained after implanted at 1, 6, and 12 months and yearly after. The frame geometry was assessed on post-implant computer tomography (CT) scanning by calculating the non-circularity [circularity ratio (minimum diameter/maximum diameter) < 0.9] and under-expansion [expansion ratio (derived external valve area/nominal external valve area)… More > Graphic Abstract

Supaporn Roymanee^1,*, Nantawan Su-angka^1,2, Worakan Promphan^2,3,*, Kanjarut Wongwaitaweewong¹, Jirayut Jarutach¹, Rujira Buntharikpornpun¹, Pimpak Prachasilchai^2,3

Congenital Heart Disease, Vol.18, No.2, pp. 169-181, 2023, DOI:10.32604/chd.2023.021238

Abstract Background: Ventricular septal defect (VSD) is the most common congenital heart disease. Transcatheter VSD closure is an effective treatment for patients with muscular and perimembranous VSD. However, there is a limit data for outlet VSD, especially impact to the aortic valve leaflet after transcatheter closure. This study aims to assess the outcomes of transcatheter closure of the outlet-type ventricular septal defect (OVSD) after 1 postoperative year. Methods: A retrospective study was performed including 50 patients who underwent transcatheter (n = 25) and surgical (n = 25) OVSD closure during the exact time frame at two medical centres. Results: The median age and body weight… More > Graphic Abstract

Jianming Wang, Qiguang Wang^*, Xiaotang Sheng, Jingsong Geng, Jiawang Xiao, Xianyang Zhu^*

Congenital Heart Disease, Vol.18, No.2, pp. 183-195, 2023, DOI:10.32604/chd.2022.021855

Abstract Objective: This study was designed to determine the long-term safety and efficacy of using the Amplatzer Duct Occluder II (ADO II) for the closure of various ventricular septal defects (VSDs). Methods: From January 2011 to December 2019, selected VSD patients were treated through transcatheter intervention using ADO II occluders. The closure results and complications from 188 patients, involving 167 perimembranous ventricular septal defects (pmVSDs), 9 intracristal VSDs, 11 post surgery residual shunts and 1 post closure residual shunt with the mean outlet diameter3.1 ± 0.8 mm under angiography, were enrolled in this study. Results: The success rate was 98.9% for… More >

Yifan Li¹, Zewen Chen², Jian Zhuang², Zhiwei Zhang^1,*

Congenital Heart Disease, Vol.17, No.5, pp. 541-549, 2022, DOI:10.32604/chd.2022.024907

Abstract A congenital coronary artery fistula (CCAF) combined with giant coronary aneurysm (CAA) is a rare congenital cardiac abnormality. We reported an 8-year-old patient who underwent transcatheter closure of both inlet and outlet of a proximal left coronary artery (LCA)-to-left ventricular (LV) fistula with CAA of 41 mm × 28 mm in diameter, during which acute occlusion of left anterior descending coronary artery (LAD) occurred immediately after device implantation at the inlet of fistula. We managed to prevent the patient from major adverse cardiac events by conservative therapy with dual antiplatelet agents instead of surgical removal of the device. The patient… More > Graphic Abstract

Pornrawee Plearntummakun¹, Chodchanok Vijarnsorn^1,*, Kritvikrom Durongpisitkul¹, Prakul Chanthong¹, Paweena Chungsomprasong¹, Supaluck Kanjanauthai¹, Thita Pacharapakornpong¹, Jarupim Soongswang¹, Thaworn Subtaweesin²

Congenital Heart Disease, Vol.17, No.4, pp. 463-478, 2022, DOI:10.32604/chd.2022.021545

Abstract Background: Congenital coronary artery fistula (CCAF) is a rare anomaly. Treatment strategies tend to close the defect with a symptomatic and significant shunt, primarily based on expert consensus and case series. Results for long-term follow-up in children are limited Methods: We conducted a retrospective study to assess clinical and imaging outcomes of children with CCAF at Siriraj Hospital, Thailand during 2000–2020. Patients with single ventricle were excluded. Treatment strategies [surgical closure (SC), and percutaneous closure (PC)] were classified and the clinical outcomes at the follow-up in 2021, including coronary thrombosis, myocardial ischemia, and the results of cardiovascular imaging were reviewed.… More > Graphic Abstract