Fengxia Shi^1,2, Yucai Tang^1,*, Dedong Ma¹, Xiangyun Shi¹, Guangbiao Zhao¹

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.10, pp. 2481-2497, 2023, DOI:10.32604/fdmp.2023.028416

Abstract In order to analyze the response of a hydraulic turbine to a variation in the operating conditions, different laws of variation in time of the mass flow rate have been considered. After validating the overall numerical framework through comparison with relevant experiments, the performances of the considered turbine have been analyzed from a fluid-dynamic point of view. The results show that different time profiles of the mass flow rate (in this work, for simplicity, referred to as “transition functions”) have a varying influence on the transient behavior of the turbine. When a quadratic function is considered for the case of… More > Graphic Abstract

Wei-Zhen Liu, Nian Liu

Oncology Research, Vol.27, No.1, pp. 1-8, 2019, DOI:10.3727/096504018X15172738893959

Abstract Propofol has been widely used in lung cancer resections. Some studies have demonstrated that the effects of propofol might be mediated by microRNAs (miRNAs). This study aimed to investigate the effects and mechanisms of propofol on lung cancer cells by regulation of miR-1284. A549 cells were treated with different concentrations of propofol, while transfected with miR-1284 inhibitor, si-FOXM1, and their negative controls. Cell viability, migration, and invasion, and the expression of miR-1284, FOXM1, and epithelial–mesenchymal transition (EMT) factors were detected by CCK-8, Transwell, qRT-PCR, and Western blot assays, respectively. In addition, the regulatory and binding relationships among propofol, miR-1284, and… More >