Weiguo Chen¹, Xiaobin Hong^1,*, Kai Chen¹, Yunyun Deng¹, Bin Zhang^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.147, No.3, 2026, DOI:10.32604/cmes.2026.082376 - 30 June 2026

Abstract Structural health monitoring (SHM) of ship piping systems is a core component of predictive maintenance strategies for complex marine engineering systems. During the detection of ship T-shaped pipes using ultrasonic guided waves, signal overlap arises from the diffusion of guided wave branches. To address this issue, an intelligent wave-guidance mechanism based on acoustic metamaterials is proposed for dynamic propagation control of ultrasonic guided waves. First, a metamaterial unit composed of a stainless steel substrate and a copper column is designed. The control of bandgap characteristics by lattice constant, column diameter, and column height is systematically… More > Graphic Abstract

Ling He, Shun Tao, Qian Wang, Yu-Pei Yin, Xin-Yu He, Shuo Shi, Chun-Yan Wang^*

Phyton-International Journal of Experimental Botany, Vol.95, No.6, 2026, DOI:10.32604/phyton.2026.081349 - 29 June 2026

Abstract As essential regulatory proteins, WRKY transcription factors participate in the regulation of plant growth, development and stress resistance; however, the functions of LoWRKY22 in the ‘Siberia’ cultivar of Lilium remain uncharacterized. In this study, LoWRKY22 was cloned and subjected to comprehensive functional analyses. Phylogenetic analysis revealed that LoWRKY22 belongs to the WRKY-IIe type subgroup, featuring a conserved WRKY domain and a C2H2-type zinc finger motif, indicating evolutionary conservation with WRKY homologs from Arabidopsis thaliana. Subcellular localization and transactivation assays confirmed its nuclear localization and transcriptional activation activity, supporting its role as a transcriptional regulator. Structural characterization of the LoWRKY22… More >

Francesco Claps^1,2,*, Miguel Ramírez-Backhaus¹, Álvaro Gómez-Ferrer¹, Juan Manuel Mascarós¹, Argimiro Collado Serra¹, Augusto Wong¹, Ana Calatrava Fons³, Miguel Ángel Climent⁴, Antonio Amodeo², Angelo Porreca⁵, Jose Rubio-Briones^1,6

Canadian Journal of Urology, Vol.33, No.3, pp. 593-602, 2026, DOI:10.32604/cju.2025.070162 - 29 June 2026

Abstract Objectives: Residual Disease after adjuvant chemotherapy for non-seminomatous germ cell tumor (NSGCT) poses a significant clinical challenge and difficulties in tailored management. This study aimed to externally validate the Heidenreich criteria among patients eligible for unilateral post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) for residual masses of NSGCT. Methods: For validation, these criteria were retrospectively applied in 23 patients undergoing PC-RPLND for residual masses of NSGCTs. In patients qualified for unilateral-modified PC-RPLND according to the Heidenreich criteria but treated with fully bilateral dissection, pathological reports were evaluated to identify teratoma or active cancer cells inside the… More >

Yang Wang^1,2, Ying Xie¹, Yiyi Ye¹, Youyang Shi¹, Feifei Li¹, Mengdie Zhu¹, Ciyi Hua¹, Yuan Xu¹, Rui Yang^1,3,*, Sheng Liu^1,4,*

Oncology Research, Vol.34, No.7, 2026, DOI:10.32604/or.2026.078051 - 16 June 2026

Abstract Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast malignancy characterized by poor clinical outcomes and limited therapeutic options. The identification of reliable biomarkers for predicting prognosis and immunotherapeutic response remains an urgent clinical need. This study aimed to develop an integrative lactylation-related gene signature to simultaneously evaluate prognostic trajectories and immunotherapeutic sensitivity in TNBC. Methods Transcriptomic and clinical data from public TNBC cohorts were systematically analyzed. Lactylation-related gene signatures were used to stratify patients via consensus clustering. A scoring model was constructed based on differentially expressed genes between clusters, and its associations with… More >

Emir Kuanyshev, Hashim Ali^*

CMC-Computers, Materials & Continua, Vol.88, No.1, 2026, DOI:10.32604/cmc.2026.080737 - 08 May 2026

Abstract Refactoring improves maintainability without altering externally observable behavior, yet it remains costly and error-prone when applied manually at scale. While large language models (LLMs) can generate plausible refactorings, practical adoption is limited by uncontrolled edit scope, inconsistent outputs under stochastic decoding, and weak traceability of why a change was produced. This paper proposes a smell-targeted, scope-bound refactoring framework for JavaScript that couples deterministic AST-based smell detection with constrained LLM transformation. The key design principle is to bind generation to explicitly detected smell instances, enforce a structured output contract (refactored code plus per-smell rationale), and log… More >

Chiao-Yang Kuan, Yung-Wei Chen^*, Jian-Hung Shen, Yen-Shen Chang

CMES-Computer Modeling in Engineering & Sciences, Vol.147, No.1, 2026, DOI:10.32604/cmes.2026.079597 - 27 April 2026

Abstract This paper investigates the vibro-acoustic coupling behavior of high-speed ball bearings and the mechanisms driving vibration and radiated noise. Ball bearings consist of an inner ring, outer ring, cage, and rolling elements, whose complex interactions—impact, friction, and geometric non-uniformities—are difficult to capture experimentally. To address this challenge, a coupled numerical approach is developed by integrating the explicit nonlinear solver LS-DYNA with the acoustic module in LMS Virtual.Lab. Simultaneously, fixed boundary constraints and no-slip contact conditions are applied in the modal analysis to identify excitation sources of structural vibrations. First, a three-sphere collision simulation is employed More >

K. Mithra^1,*, Prem Kumar Santhanam²

Journal of Intelligent Medicine and Healthcare, Vol.4, pp. 87-97, 2026, DOI:10.32604/jimh.2026.080288 - 24 April 2026

Abstract Background: Retinal fundus imaging is central to early diagnosis of sight-threatening conditions, including diabetic retinopathy, glaucoma, and retinal vein occlusion. Clinical utility is compromised by non-uniform illumination, motion blur, and low contrast—artefacts that reduce diagnostic accuracy. Effective image enhancement is a prerequisite for reliable computer-aided ophthalmic diagnosis. Methods: This paper proposes a two-stage enhancement pipeline combining luminosity correction via HSV colour space decomposition with Contrast Limited Adaptive Histogram Equalization (CLAHE) on the Value (V) channel. Validation is conducted on three publicly available benchmarks: DRIVE (40 images), STARE (20 images), and CHASEDB1 (28 images). Quantitative metrics… More >

Wei Xu^1,#, Yuanyuan Zhang^2,#, Yizhi Ge^2,*, Yesong Guo^2,*

Oncology Research, Vol.34, No.5, 2026, DOI:10.32604/or.2026.075314 - 22 April 2026

Abstract Objectives: Radio-resistance hinders the effectiveness of radiotherapy for treating colorectal cancer (CRC) patients. Metadherin (MTDH) is proposed to exert a pivotal role in resistance to radiotherapy in various malignancies. This study aims to investigate the precise impact of MTDH on CRC radio-resistance. Methods: Through a fusion of 14 machine learning algorithms and SHapley Additive exPlanations (SHAP) interpretability analysis, we pinpointed MTDH as a pivotal gene implicated in radio-resistance mechanisms. Subsequently, we investigated MTDH expression in CRC tissues using single-cell RNA sequencing data (scRNA-seq) and bulk transcriptomic data. MTDH level was also examined in tissues from… More >

Ya-Ling Yang^1,#, Ying-Hsien Huang^2,#, Hung-Yu Lin^3,4,*

Oncology Research, Vol.34, No.5, 2026, DOI:10.32604/or.2026.075284 - 22 April 2026

Abstract Background: Hepatocellular carcinoma (HCC) presents with poor treatment outcomes, creating an urgent need for novel biomarkers to improve diagnosis, prognosis, and precision medicine. While the MYB family of oncogenes is implicated in cancer, the role and regulatory mechanisms of its member, particularly MYB proto-oncogene like 2 (MYBL2), remain underexplored in HCC. Therefore, this study aimed to systematically validate the clinical significance of MYBL2, elucidate its functional role in tumor progression and drug sensitivity, and identify its upstream regulatory mechanisms using an integrative machine learning and experimental framework. Methods: We applied an integrative pipeline combining LASSO-based… More > Graphic Abstract

Benedict Djouboussi^1,*, Elie Fute Tagne^1,2

Journal of Cyber Security, Vol.8, pp. 171-187, 2026, DOI:10.32604/jcs.2026.079617 - 15 April 2026

Abstract The Distributed Network Protocol 3 (DNP3) is widely deployed in SCADA-based microgrids; however, it was not originally designed to meet the cybersecurity requirements of modern decentralized energy infrastructures. Although DNP3 Secure Authentication (DNP3-SA) introduces HMAC-based session-level protection, it does not ensure fragment-level integrity, leaving the protocol vulnerable to fragmentation disruption, replay attacks, and sequence manipulation. Such vulnerabilities can cause desynchronization between master and outstation devices, compromising the operational reliability of distributed energy resources. This paper proposes DNP3Chain, a blockchain-enabled framework that provides real-time fragment-level validation and enforces end-to-end message integrity in DNP3 communications. An OpenDNP3-based… More >