Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (100)
  • Open Access

    ARTICLE

    Prognostic prediction and expression validation of NSD3 in pan-cancer analyses

    SHA LI1,2,#, YAQIONG LIU3,#, CHAOLING YAO1, ANJI XU1, XIAOLING ZENG4, YUXIN GE4, XIAOWU SHENG4, HAILIN ZHANG1,2, XIAO ZHOU1,2,*, YING LONG1,2,*

    BIOCELL, Vol.47, No.5, pp. 1003-1019, 2023, DOI:10.32604/biocell.2023.027209 - 10 April 2023

    Abstract Background: Nuclear receptor binding SET domain protein-3 (NSD3) is a histone lysine methyltransferase and a crucial regulator of carcinogenesis in several cancers. We aimed to investigate the prognostic value and potential function of NSD3 in 33 types of human cancer. Methods: The data were obtained from The Cancer Genome Atlas. Kaplan-Meier analysis, CIBERSORT, gene set enrichment analysis, and gene set variation analysis were performed. The expression of NSD3 was measured using quantitative real-time polymerase chain reaction and western blot. Results: The expression of NSD3 was altered in pan-cancer samples. Patients with higher levels of NDS3 generally had… More >

  • Open Access

    ARTICLE

    Dynamic Modeling and Sensitivity Analysis for an MEA-Based CO2 Capture Absorber

    Hongwei Guan1, Lingjian Ye2,3,*, Yurun Wang2, Feifan Shen4, Yuchen He3

    Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 3535-3550, 2023, DOI:10.32604/iasc.2023.036399 - 15 March 2023

    Abstract The absorber is the key unit in the post-combustion monoethanolamine (MEA)-based carbon dioxide (CO2) capture process. A rate-based dynamic model for the absorber is developed and validated using steady-state experimental data reported in open literature. Sensitivity analysis is performed with respect to important model parameters associated with the reaction, mass transport and physical property relationships. Then, a singular value decomposition (SVD)-based subspace parameter estimation method is proposed to improve the model accuracy. Finally, dynamic simulations are carried out to investigate the effects of the feed rate of lean MEA solution and the flue inlet conditions. Simulation More >

  • Open Access

    ARTICLE

    Spectral Analysis and Validation of Parietal Signals for Different Arm Movements

    Umashankar Ganesan1,*, A. Vimala Juliet2, R. Amala Jenith Joshi3

    Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 2849-2863, 2023, DOI:10.32604/iasc.2023.033759 - 15 March 2023

    Abstract Brain signal analysis plays a significant role in attaining data related to motor activities. The parietal region of the brain plays a vital role in muscular movements. This approach aims to demonstrate a unique technique to identify an ideal region of the human brain that generates signals responsible for muscular movements; perform statistical analysis to provide an absolute characterization of the signal and validate the obtained results using a prototype arm. This can enhance the practical implementation of these frequency extractions for future neuro-prosthetic applications and the characterization of neurological diseases like Parkinson’s disease (PD).… More >

  • Open Access

    ARTICLE

    Selection and Validation of Reference Genes for Normalization of RT-qPCR Analysis in Developing or Abiotic-Stressed Tissues of Loquat (Eriobotrya japonica)

    Shoukai Lin1,2,#, Shichang Xu1,#, Liyan Huang1, Fuxiang Qiu1, Yihong Zheng1, Qionghao Liu1, Shiwei Ma1,2, Bisha Wu1,2, Jincheng Wu1,2,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.4, pp. 1185-1201, 2023, DOI:10.32604/phyton.2023.026752 - 06 January 2023

    Abstract Loquat (Eriobotrya japonica Lindl.) is a subtropical evergreen fruit tree that produces fruits with abundant nutrients and medicinal components. Confirming suitable reference genes for a set of loquat samples before qRT-PCR experiments is essential for the accurate quantification of gene expression. In this study, eight candidate reference genes were selected from our previously published RNA-seq data, and primers for each candidate reference gene were designed and evaluated. The Cq values of the candidate reference genes were calculated by RT-qPCR in 31 different loquat samples, including 12 subgroups of developing or abiotic-stressed tissues. Different combinations of stable… More >

  • Open Access

    ARTICLE

    Selection and validation of reference genes for quantitative real-time polymerase chain reaction analyses of Serratia ureilytica DW2

    FENGLIN BAI1,2,#, BIANXIA BAI1,2,#, TINGTING JIN1,2, GUIPING ZHANG1,2, JIAHONG REN1,2,*

    BIOCELL, Vol.47, No.3, pp. 647-656, 2023, DOI:10.32604/biocell.2023.024758 - 03 January 2023

    Abstract Background: Serratia ureilytica DW2 is a highly efficient phosphate-solubilizing bacteria isolated from Codonopsis pilosula rhizosphere soil that can promote the growth of C. pilosula; nonetheless, until now, no validated reference genes from the genus Serratia have been reported that can be used for the normalization of quantitative real-time polymerase chain reaction (RT–qPCR) data. Methods: To screen stable reference genes of S. ureilytica DW2, the expression of its eight candidate reference genes (16S rRNA, ftsZ, ftsA, mreB, recA, slyD, thiC, and zipA) under different treatment conditions (pH, temperature, culture time, and salt content) was assayed by RT–qPCR. The expression stability of these genes was analyzed using… More >

  • Open Access

    ARTICLE

    Offshore Software Maintenance Outsourcing Process Model Validation: A Case Study Approach

    Atif Ikram1,2,*, Masita Abdul Jalil1, Amir Bin Ngah1, Adel Sulaiman3, Muhammad Akram3, Ahmad Salman Khan4

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5035-5048, 2023, DOI:10.32604/cmc.2023.034692 - 28 December 2022

    Abstract The successful execution and management of Offshore Software Maintenance Outsourcing (OSMO) can be very beneficial for OSMO vendors and the OSMO client. Although a lot of research on software outsourcing is going on, most of the existing literature on offshore outsourcing deals with the outsourcing of software development only. Several frameworks have been developed focusing on guiding software system managers concerning offshore software outsourcing. However, none of these studies delivered comprehensive guidelines for managing the whole process of OSMO. There is a considerable lack of research working on managing OSMO from a vendor’s perspective. Therefore,… More >

  • Open Access

    ARTICLE

    Cross-Validation Convolution Neural Network-Based Algorithm for Automated Detection of Diabetic Retinopathy

    S. Sudha*, A. Srinivasan, T. Gayathri Devi

    Computer Systems Science and Engineering, Vol.45, No.2, pp. 1985-2000, 2023, DOI:10.32604/csse.2023.030960 - 03 November 2022

    Abstract The substantial vision loss due to Diabetic Retinopathy (DR) mainly damages the blood vessels of the retina. These feature changes in the blood vessels fail to exist any manifestation in the eye at its initial stage, if this problem doesn’t exhibit initially, that leads to permanent blindness. So, this type of disorder can be only screened and identified through the processing of fundus images. The different stages in DR are Micro aneurysms (Ma), Hemorrhages (HE), and Exudates, and the stages in lesion show the chance of DR. For the advancement of early detection of DR… More >

  • Open Access

    ARTICLE

    NDN Content Poisoning Mitigation Using Bird Swarm Optimization and Trust Value

    S. V. Vijaya Karthik*, J. Arputha Vijaya Selvi

    Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 833-847, 2023, DOI:10.32604/iasc.2023.025404 - 29 September 2022

    Abstract Information-Centric Networking (ICN) is considered a viable strategy for regulating Internet consumption using the Internet’s underlying architecture. Although Named Data Networking (NDN) and its reference-based implementation, the NDN Forwarding Daemon (NFD), are the most established ICN solutions, their vulnerability to the Content Poisoning Attack (CPA) is regarded as a severe threat that might dramatically impact this architecture. Content Poisoning can significantly minimize the impact of NDN’s universal data caching. Using verification signatures to protect against content poisoning attacks may be impractical due to the associated costs and the volume of messages sent across the network,… More >

  • Open Access

    ARTICLE

    Numerical Modelling of Drying Induced Cracks in Wood Discs Using the Extended Finite Element Method

    Zongying Fu1, Yongdong Zhou1, Tingguo Yan2, Yun Lu1,*

    Journal of Renewable Materials, Vol.11, No.1, pp. 93-102, 2023, DOI:10.32604/jrm.2023.021808 - 10 August 2022

    Abstract Drying crack is a common phenomenon occurring during moisture discharge from wood, reducing efficient wood utilization. Drying crack is primarily caused by drying stress, and the reasonable methods for determining drying stress are sparse. In this study, the initiation and propagation of cracks during wood discs drying were simulated using the extended finite element method (XFEM). The distribution of drying stress and displacement was analyzed at different crack conditions based on the simulation results. This study aimed to solve the problem of the limitation of drying stress testing methods and provide a new idea for More >

  • Open Access

    ARTICLE

    Implementation of a solar model and shadow plotting in the context of a 2D GIS

    A validation based on radiometric measurements

    Thomas Leduc, Xenia Stavropulos-Laffaille, Ignacio Requena-Ruiz

    Revue Internationale de Géomatique, Vol.31, No.2, pp. 241-263, 2022, DOI:10.3166/rig31.241-263

    Abstract The adaptation of public spaces to episodes of intense heat is now a major challenge for cities. With this in mind, this article presents a contribution aimed at delineating and handling the shadows on the ground or in a horizontal plane at a given height, whether it comes from buildings, street furniture or the tree cover. After a comparison with shadows obtained via two reference tools, we present two urban sites that mix shadows of different origins and, in addition, different indicators. The results of the simulations are compared with pyranometric surveys carried out on More >

Displaying 31-40 on page 4 of 100. Per Page